Prenatal diagnosis and management of anterior abdominal wall defects in the West of Scotland

An attempt was made to identify all the cases of abdominal wall defects occurring in the West of Scotland over a 7-year period to determine the current incidence, prenatal diagnosis, management, and prognosis for fetuses and neonates with abdominal wall defects. Cases were identified because they presented either for prenatal diagnosis, or to the Department of Pathology following termination or spontaneous pregnancy loss, or as neonates to the Neonatal Surgical Department. The incidence of abdominal wall defects was found to be 1 in 2500 births. Exomphalos was diagnosed before birth in 66 per cent of cases, and in 30 per cent of cases it was associated with another major abnormality. There was a 20 per cent intact survival in the cases diagnosed prenatally who had no fetal anomaly and who opted to continue with the pregnancy. Gastroschisis was diagnosed before delivery in 70 per cent of cases, and in the group who continued with the pregnancy there was an intact survival of 77 per cent. Body stalk anomalies were all diagnosed prenatally and terminated. Maternal serum alpha-fetoprotein was elevated in 89 per cent of the cases with exomphalos and in 100 per cent of the cases with gastroschisis and body stalk anomalies in which it was tested.     

玻璃纤维-砂浆管试件动态拉伸破坏特性试验研究

为了探究动载作用下GFRP（玻璃纤维）-砂浆管的动态拉伸破坏特性,采用分离式SHPB试验装置对2种空心率的水泥砂浆管和GFRP-砂浆管进行动态拉伸试验。结果表明:空心率越小、冲击气压和壁厚越大,试件峰值抗拉强度越大;GFRP-砂浆管的峰值抗拉强度随GFRP管壁厚的增大而不断增大,在空心率为0.292时,峰值抗拉强度随GFRP管壁厚增大呈对数函数递增,而在空心率0.187时,峰值抗拉强度随GFRP管壁厚增大呈指数函数递增;无GFRP管时水泥砂浆管呈对称四块破碎,GFRP-砂浆管在0.5~0.7 MPa冲击气压下仅有细小裂纹产生,在0.8 MPa冲击气压下,与入射杆接触部分产生“楔形”破坏,但总体保持为管状、破坏程度仍低于水泥砂浆管,表明GFRP管对水泥砂浆管具有较好的保护作用,可有效提高其动态抗拉强度。     

Normal and abnormal fetal cardiac anatomy

The heart is often perceived as a difficult organ to understand by ultrasound during fetal life. This is undoubtedly reflected in the low detection rate of cardiac abnormalities as compared to those of most other organ systems in the fetus. In this article we start by updating classical concepts of cardiac embryology, many of which were previously difficult to understand since they were overly simplistic or purely observational. We then lead on to the structure and growth of the fully formed fetal heart where we review the anatomy and ultrasound appearances in detail and provide comparisons with major abnormalities. We emphasise the fact that a solid understanding of cardiac anatomy can enable those involved in fetal medicine to make full use of the views of the heart that are obtained by ultrasound and which are often only transient. Copyright © 2004 John Wiley & Sons, Ltd.     

LD30大口径薄壁无缝管成形工艺

介绍了LD30大直径无缝薄壁筒采用热拉伸坯经变薄旋压成形工艺 ,讨论了其工艺过程 ,工艺参数和应用范围等。     

薄壁钢管弯曲模具设计

分析了薄壁钢管弯曲时产生瘪皱的原因,提出了弯管模具关键参数的设计计算方法,保证了弯管质量.     

Leaf area development, dry weight accumulation and solar energy conversion efficiencies of Phaseolus vulgaris L. under different soil moisture levels near Nairobi, Kenya

ＩｎｔｒｏｄｕｃｔｉｏｎＫｅｎｙａ○ｓｈｉｇｈｐｏｐｕｌａｔｉｏｎｇｒｏｗｔｈｒａｔｅｈａｓｃｒｅａｔｅｄｐｒｅｓｓｕｒｅｏｎｔｈｅｈｉｇｈｐｏｔｅｎｔｉａｌａｒｅａｓ．Ｔｈｉｓｈａｓｒｅｓｕｌｔｅｄｉｎｔｈｅｍｉｇｒａｔｉｏｎｏｆｐｅｏｐｌｅｔｏｕｎｃｕｌｔｉｖａｔｅｄ“ｍａｒｇｉｎａｌ”ｌａｎｄｓｗｈｉｃｈｍａｋｅｕｐａｂｏｕｔ８０％ｏｆｔｈｅｃｏｕｎｔｒｙａｎｄａｒｅｐｒｅｄｏｍｉｎａｎｔｌｙｏｆｌｏｗａｇｒｉｃｕｌｔｕｒａｌｐｒｏｄｕｃｔｉｖｉｔｙ（Ｈｏｒｎｅｔｚ，１９９０）．Ｔｈｅｓｅ…     

Prenatal sonographic diagnosis of diastematomyelia in a diabetic woman

Diastematomyelia is a structural anomaly which concerns primarily the spine and secondarily the nervous structures contained in it. A case of early prenatal diagnosis (20th week) by ultrasound of diastematomyelia with associated diplomyelia in a diabetic woman is reported. Radiological and pathological examination of the fetus after therapeutic abortion confirmed the diagnosis.     

Amniocentesis carried out for neural tube indications in South Wales 1973–1981: Outcome of pregnancies and findings in the malformed abortuses

The 2872 second trimester amniocenteses followed by amniotic alphafetoprotein (AFP) estimations carried out in South Wales between 1973 and 1981 on women known to be at increased risk for neural tube defect (NTD) and those who had a raised serum AFP level in an NTD screening programme led to the identification of 78 pregnancies of a fetus with anen-cephalus, 61 with ‘open’ spina bifida, 8 with gastroschisis, 3 with exomphalos, 2 with encephalo-cele and 6 with chromosome abnormality. Pregnancies of fetuses having 4 potentially identifiable NTDs were missed because of an equivocal AFP level and there were two false positive results leading to the termination of one normal fetus. It is emphasized that both the latter problems of one normal fetus. It is emphasized that both the latter problems would not have occurred had gel-electrophoresis for isoenzymes of acetyl cholinesterase been available. Follow-up of pregnancies showed that 7 children with ‘closed’ NTD and 3 with congenital hydrocephalus were born. The anencephalics and the ‘open’ spina bifidas had a more florid lesion than is usual at term. Nearly all the spina bifidas were associated with hydrocephalus, often severe and with an obvious Arnold-Chiari malformation. All but 13 had leg or back deformation or malformations in other systems, mostly in the renal tract.     

高温合金GH4169管材挤压工艺及组织分析

对高温合金GH4169管材挤压成形进行了工艺研究.确定了GH1140管材挤压成形工艺参数,分析了GH4169管材挤压力能参数变化规律.分析了管材挤压对组织性能的影响。研究结果发现,GH4169管材挤压成形时必须严格控制坯料温度、模具预热温度、润滑方式、挤压速度、挤压比等工艺参数。     

Prenatal assessment of anterior abdominal wall defects and their prognosis

Eighty-eight cases of abdominal wall defect with and without other lesions were ascertained by reviewing all labour room records in the West of Scotland, all surgical admissions to the Royal Hospital for Sick Children, Yorkhill, and all post mortems at Royal Hospital for Sick Children between 1978 and 1981. The affected cases comprised 39 terminations of pregnancy (17 of anterior abdominal wall defect without neural tube defect). 20 spontaneous stillbirths and 29 livebirths. All 10 cases of body stalk anomaly, 37.5 per cent of 16 gastroschisis cases and 53 per cent of 62 exomphalos cases had additional severe abnormalities. Abnormal karyotypes were present in seven out of 19 exomphalos cases but all karyotypes from 10 gastroschisis and 6 body stalk anomaly cases were normal. No correlation was found between the maternal serum AFP levels, the amniotic AFP levels and acetylcholinesterase results and the size of the lesion. It is proposed that anterior abdominal wall defects detected prenatally should have chromosome analysis and careful ultrasound to exclude associated severe anomalies before coming to a decision about termination. This policy was implemented in six pregnancies complicated by fetal gastroschisis without severe associated anomalies which were identified in the second trimester and continued to term. Immediate surgical repair was achieved in each case, although two of the infants succumbed from later complications of gastroschisis closure and one from respiratory distress syndrome. The remaining three infants made a satisfactory recovery.