紫露草微核效应与SO2和NOx剂量间关系的试验研究

利用紫露草微核技术对大气中重要的污染物ＳＯ２和ＮＯｘ进行了室内外试验。结果表明,紫露草对大气中ＳＯ２和ＮＯｘ较敏感,紫露草微核频率ＭＣＮ％（效应ｙ）与ＳＯ２、ＮＯｘ的浓度（剂量ｘ）的关系在一定的范围内呈正相关。对于ＳＯ２当浓度在０．００－３．７５ｍｇ／ｍ＾３之间时,对应的微核频率ｙ＝８．３８＋４．３８ｘ,ｒ＝０．９１;对于ＮＯｘ当浓度在０．００－１．００ｍｇ／ｍ＾３之间时,对应的微核频率ｙ＝４．８     

定量构效关系在环境化学中的应用

本文介绍近十年来国外文献中定量构效关系(QSAR)在环境化学中应用典型实例及作者的五个方面工作,旨在说明QSAR方法确是化学品安全评价的有用工具之一。文中探讨该方法应用的局限性及将来可能的进展。     

信息理论指数及其在有机磷农药毒性预测研究中的应用

为探讨化合物结构与毒性关系研究方法,将定量描述分子结构特征的信息理论指数、价分子连续性指数应用于有机磷农药毒性预测研究,提出了基团信息参数。运用判别分析、多元非线性回归分析,依据１１４种有机磷农药急性毒性数据资料,按动物不同给药途径,分别建立定性、定量预测模型,定性判别回代符合率均在８３．３３％以上,定量回归方程相关指数Ｒ＾２均在０．８１以上,回归残差呈正态分布。预测分析,预测值均在ＬＤ５０测定值     

取代芳烃对三种生物急性毒性的QSAR研究

根据成键原子的结构特征定义其生物活性点价为δiA,并在分子拓扑理论基础上由δiA 建构新的连接性指数nH =∑ (δiA·δAj·δAk… ) 0 .5,其中 ,0价指数0 H =∑ (δiA) 0 .5,1价指数1 H =∑ (δiA·δAj) 0 .5。以0 H、1 H及指示变量I为结构描述符 ,籍助多元线性回归技术 ,分别建立了取代芳烃 (含Cl、Br、CH3、OH、NH2 、NO2 等 )对发光菌、大型蚤、呆鲦鱼的QSAR模型 :以模型的估算结果均优于文献结果 ,而且计算简单 ,应用方便 ,为定量评估和预测同类型其它化合物的生物毒性提供了参考依据。     

土地功能视角下的土地资源人口承载力研究

长期以来,国内外对土地资源人口承载力的研究基本上都是围绕“耕地 粮食 人口”这一思路而展开的。在当前经济全球化、快速城市化的背景下,单一评价方法难以全面反映社会发展实际。从土地功能视角出发提出土地资源人口承载力评价的新体系：基于土地粮食视角的人口承载力、基于建设用地视角的人口承载力、基于土地经济关系视角的人口承载力。首次将土地经济关系引入土地资源承载力评价中,利用不同土地类型与国民经济部门的关系进行人口测算,可以真实反映当今经济社会下人口承载的实际状态。以攀枝花市、六盘水市为例进行了实证研究,仅从本区域评价结果来看,原有传统的土地粮食人口承载能力在此次评价中并不构成最大限制因素,而是建设用地或者土地经济关系等因素决定了人口承载力,这也证明了土地资源人口承载力研究方法的可行性和相对合理性     

Toxicity of 58 substituted anilines and phenols to algae Pseudokirchneriella subcapitata and bacteria Vibrio fischeri: comparison with published data and QSARs

A congeneric set of 58 substituted anilines and phenols was tested using the 72-h algal growth inhibition assay with Pseudokirchneriella subcapitata and 15-min Vibrio fischeri luminescence inhibition assay. The set contained molecules substituted with one, two or three groups chosen from -chloro, -methyl or -ethyl. For 48 compounds there was no REACH-compatible algal toxicity data available before. The experimentally obtained EC50 values (mg L⁻¹) for algae ranged from 1.43 (3,4,5-trichloroaniline) to 197 (phenol) and for V. fischeri from 0.37 (2,3,5-trichlorophenol) to 491 (aniline). Only five of the tested 58 chemicals showed inhibitory effect to algae at concentrations >100 mg L⁻¹, i.e. could be classified as “not harmful”, 32 chemicals as “harmful” (10-100 mg L⁻¹) and 21 as “toxic” (1-10 mg L⁻¹). The occupied para-position tended to increase toxicity whereas most of the ortho-substituted congeners were the least toxic. As a rule, the higher the number of substituents the higher the hydrophobicity and toxicity. However, in case of both assays, the compounds of similar hydrophobicity showed up to 30-fold different toxicities. There were also assay/organism dependent tendencies: phenols were more toxic than anilines in the V. fischeri assay but not in the algal test. The comparison of the experimental toxicity data to the data available from the literature as well as to QSAR predictions showed that toxicity of phenols to algae can be modeled based on hydrophobicity, whereas the toxicity of anilines to algae as well as toxicity of both anilines and phenols to V. fischeri depended on other characteristics in addition to logK_ow.     

Elemental distribution in the edible leaves of Celosia trigyna from the western and northern regions of Nigeria

Celosia trigyna, which belongs to the plant family Amaranthaceae, is a plant used in traditional medicine to treat several conditions such as sores, chest pains, diarrhoea and menstrual cramps in many countries in Africa. It is also consumed by the local people in Nigeria as soups, sauces and stews. In this study, the distribution and bioaccumulation of the elements in C. trigyna species and growth soil from the western and northern regions of Nigeria was investigated to determine the effects of geographical location on the uptake of elements by the plant. Elemental concentrations in the leaves from the western region were found to be in decreasing order of Ca?>?Mg?>?Fe?>?Mn?>?Zn?>?Cu?>?Pb?>?As?>?Ni. Concentrations of elements in the leaves from the northern region were found to be in decreasing order of Ca?>?Mg?>?Fe?>?Mn?>?Zn?> Cu?>?As?>?Pb?>?Ni?>?Co?>?Cd. Proximate analysis of leaves from both regions compared well with the recommended dietary allowance making the leaves safe for human consumption. Principal component analysis was used to group elements having the same sources irrespective of their geographical locations. Cd, Co and Cr were not detected in the leaves from the western region. Concentrations of As and Pb were above maximum permissible limits in both regions, while Ayegunle and Bida (in the northern region) had the highest concentrations of Cd. The high level of these toxic metals may be attributed to anthropogenic activities. It is therefore important that the Nigerian agricultural extension system emphasizes the dangers of heavy metal contamination in leafy vegetables to farmers. Activities of the manufacturing industries in the study area should be adequately monitored under standard environmental protection laws.     

城镇化与粮食生产技术效率的互动关系研究

城镇化和粮食生产在我国都占据着十分重要的地位,供给侧改革背景下如何提升粮食生产技术效率,促进城镇化和粮食生产的协调发展,具有十分重要的意义。文章以1998—2014年全国29个省(市、区)为研究对象,分别采用熵值法和DEA方法对城镇化指标体系和粮食生产技术效率指标体系进行了构建,其中,城镇化指标体系被细分为人口城镇化、土地城镇化和经济城镇化三个子系统,在此基础上采用面板协整方程、误差修正模型、脉冲响应方程和方差分解模型对城镇化和粮食生产技术效率之间的互动关系进行了分析。研究发现:(1)城镇化和粮食生产技术效率之间的长期均衡关系对短期的影响存在功能区差异。对于全国层面、粮食主产区以及粮食主销区,长期正面效应大于短期负面效应,对于粮食平衡区,长期正面效应小于短期正面效应。(2)总体来说,城镇化和粮食生产技术效率响应之间的变动为正,并逐渐趋向一个稳定的水平。(3)城镇化和粮食生产技术效率的预测方差受自身的冲击要更高,且二者对预测方差的贡献度呈现出区域差异。最后,提出要加强粮食生产的科技投入和资本投入,实施"藏粮于技"和"藏粮于地"策略,并加强对粮食生产领域的生态环境治理,提高粮食的可持续发展能力。此外,因地制宜制定合适的城镇化和粮食发展策略,适当引导和鼓励社会资本参与粮食生产项目和社会化服务建设,促进粮食产业的现代化。     

QSAR models for predicting the toxicity of halogenated phenols to Tetrahymena

Halogenated phenols are industrial pollutants which may cause serious damage to the environment. In this work, a two-dimensional (2D) and two three-dimensional (3D) quantitative structure–activity relationship models for the toxicity prediction of halogenated phenols in Tetrahymena were developed. The structural factors that mainly influence toxicity were explored, agreeing with previously reported data. The results obtained with the 3D model were in agreement with those obtained with the 2D model. According to our findings, several new molecules with different predicted activities were designed.