多球面滑动摩擦隔震支座的设计原理和理论模型

介绍一种用于桥梁抗震的多球面滑动摩擦隔震支座,分析这种支座的设计原理,阐明其构造特点,分析了其工作机理和滑动隔震过程,并由此建立了该隔震支座的力—位移关系恢复力模型。理论分析表明,该支座除具备完善的减隔震支座所要求的功能之外,还构造简单、隔震机理清楚、数学物理模型明确,能够满足实际应用中简单性的要求。此外,该支座在不同强度的外部激励下,可以表现出不同的阻尼和刚度。并且具备单独优化性能,即该支座可以基于多性能目标或多水准地震,对于给定的桥梁隔震系统的各个参数分别进行优化。这两种特性使得该支座适合多水准地震动作用下,基于性能的隔震桥梁抗震设计。     

试论环境政治学的两大分支及其关系

环境政治学是培养环境人才的必要课程之一。通过探讨环境政治学的概念和研究对象,论述环境政治包括国内环境政治和国际环境政治这两个分支四个方面的联系。     

First report on development of quantitative interspecies structure-carcinogenicity relationship models and exploring discriminatory features for rodent carcinogenicity of diverse organic chemicals using OECD guidelines

Different regulatory agencies in food and drug administration and environmental protection worldwide are employing quantitative structure-activity relationship (QSAR) models to fill the data gaps related with properties of chemicals affecting the environment and human health. Carcinogenicity is a toxicity endpoint of major concern in recent times. Interspecies toxicity correlations may provide a tool for estimating sensitivity towards toxic chemical exposure with known levels of uncertainty for a diversity of wildlife species. In this background, we have developed quantitative interspecies structure-carcinogenicity correlation models for rat and mouse [rodent species according to the Organization for Economic Cooperation and Development (OECD) guidelines] based on the carcinogenic potential of 166 organic chemicals with wide diversity of molecular structures, spanning a large number of chemical classes and biological mechanisms. All the developed models have been assessed according to the OECD principles for the validation of QSAR models. Consensus predictions for carcinogenicity of the individual compounds are presented here for any one species when the data for the other species are available. Informative illustrations of the contributing structural fragments of chemicals which are responsible for specific carcinogenicity endpoints are identified by the developed models. The models have also been used to predict mouse carcinogenicities of 247 organic chemicals (for which rat carcinogenicities are present) and rat carcinogenicities of 150 chemicals (for which mouse carcinogenicities are present). Discriminatory features for rat and mouse carcinogenicity values have also been explored.     

近50年鄱阳湖流域实际蒸发量的变化及影响因素

流域的实际蒸发是水文循环和水量平衡的重要组成部分,分析鄱阳湖流域的实际蒸发对该流域水资源研究有重要意义。选取应用范围较广的互补相关蒸发模型,估算鄱阳湖流域9个气象站1955～2001年实际蒸发量,采用统计学方法分析该时段流域实际蒸发的年内变化特征。结果表明:流域蒸发年内呈单峰型变化,峰值出现在7月份;季节变化上,夏季最大,冬季最小,春季高于秋季。选用Db3小波函数分析9站蒸发量变化趋势,结果表明:该流域蒸发量在计算时段内呈现逐步下降趋势,1998年左右转折,之后下降速度变缓。与流域同期降水量、潜在蒸发量以及太阳辐射、温度、水汽压差和风速等气象要素的对比分析认为,实际蒸发量下降的主要是由太阳净辐射和风速的下降引起的.     

关于对水质分析中氨氮、总氮与总磷校准曲线的绘制与计算公式的探讨

本文从不同标液体积下的氨氮含量与校正吸光度、不同标液体积下的浓度与校正吸光度、不同标液体积下的校正吸光度与氨氮含量的一次函数关系中推导相关计算公式,让初学者灵活掌握与运用相关公式。     

循环荷载下南京片状细砂的动应力—应变关系

以片状颗粒成分为主的片状结构砂与常用的圆形颗粒标准石英砂相比,在物理力学特性上有显著的差异。循环荷载作用下,饱和砂土振动孔压上升会导致土体刚度发生软化,当振动孔压累积达到一定水平时,会产生液化现象,从而引起土体结构发生破坏。采用英国WFI动三轴仪,研究了南京片状细砂在循环荷载作用下,静偏应力水平、循环应力比水平和循环次数对其动应力—应变关系的影响,考虑每一次循环过程中动应力—应变关系滞回曲线的卸载及再加载割线动剪切模量G_(sec)和最大割线模量G_(max)的变化特性,建立了动剪模量软化的经验公式;静偏应力水平对动剪模量软化有显著影响,随着循环次数的增加,动应力—应变滞回圈逐渐向应变累积方向滑移和向应变轴方向倾斜,且彼此分离;考虑循环软化特性,采用修正的Masing准则,描述了循环荷载下南京片状细砂的动应力—应变关系。     

有毒物质低剂量刺激作用的研究进展

有毒物质低剂量刺激作用(hormesis)是一个有争议的毒理学问题.本文综述了hormesis的研究进展、关键学术问题以及可能的作用机制,并对有关hormesis的机理研究与环境内分泌干扰物研究和风险评价理论及方法之间的关系进行了讨论,提出了其中存在的关键科学问题和可能的研究方向.