ASSESSING FLOOD MITIGATION ALTERNATIVES IN SHIJR AREA IN METROPOLITAN TAIPEI1

The Keelung River Basin in northern Taiwan lies immediately upstream of the Taipei metropolitan area. The Shijr area is in the lower basin and is subject to frequent flooding. This work applies micromanagement and source control, including widely distributed infiltration and detention/ retention runoff retarding measures, in the Wudu watershed above Shijr. A method is also developed that combines a genetic algorithm and a rainfall runoff model to optimize the spatial distribution of runoff retarding facilities. Downstream of Wudu in the Shijr area, five dredging schemes are considered. If 10‐year flood flows cannot be confined in the channel, then a levee embankment that corresponds to the respective runoff retarding scheme will be required. The minimum total cost is considered in the rule to select from the regional flood mitigation alternatives. The results of this study reveal that runoff retarding facilities installed in the upper and middle parts of the watershed are most effective in reducing the flood peak. Moreover, as the cost of acquiring land for the levee embankment increases, installing runoff retarding measures in the upper portion of the watershed becomes more economical.     

太湖流域主要城市洪涝灾害生态风险评价

太湖流域有上海，苏州，无锡，常州，镇江，杭州，嘉兴，湖州八个大中城市，是我国产业最集中，工农业最发达的地区之一，但该地区洪涝灾害频繁，这不仅制约了流域中各城市经济的发展，还严重威胁到该地区城市的生存平衡，本文根据生存风险评价原理，结合太湖流域的自然特点，提出成因分析法的指标模型。并通过分析太湖流域八个大中城市的汛期降雨量和地形地貌因子对洪涝灾害生态风险的影响度，得出各个城市洪涝灾害的生态风险度，最后还根据各城市风险度的大小及其主导因素的不同，提出了如何管理洪涝灾害生态风险的建议。     

灰关联分析在故障树诊断中的应用

介绍一种灰色诊断法。在故障诊断模式识别中,运用灰关联分析,依据故障树的底事件重要度,通过关联度计算及排序,对故障树分析中,各种故障模式发生的可能性大小作出了准确的判断,从而为处理事故的先后、缓急提供了依据。     

Trisomy 15 mosaicism owing to familial reciprocal translocation t(1;15): implication for prenatal diagnosis

We describe a 4-year-old female child with severe global mental retardation, myoclonic epilepsy, proximal hypotonia and dysmorphisms, whose prenatal diagnosis following amniocentesis revealed a constitutional female karyotype carrying a t(1;15)(q10;p11) familial reciprocal translocation. Post-natal high-resolution karyotype, Fluorescence in situ hybridization (FISH) screening for subtelomeric rearrangements, VNTR search for UPD15 in the blood and fibroblast, and WCP1 and 15 in the mother, failed to provide an explanation for the complex clinical phenotype of the proband. Since the pachytene configuration of the translocated chromosomes defines a high probability of 3:1 segregation, an extensive workup was undertaken to look for a possibly cryptic mosaicism. Four percent of the cells with trisomy 15 was found in the peripheral blood lymphocytes examined by classical cytogenetic technique and interphase FISH analysis. The clinical features associated with cryptic trisomy 15 mosaicism and the problems concerning prenatal diagnosis and genetic counselling for carriers of translocations at high risk of 3:1 segregation are discussed. Copyright © 2006 John Wiley & Sons, Ltd.     

Hyper-echogenic colon: a prenatal sign of cystinuria?

We suggest the term ‘hyper-echogenic colon’ to describe a hyperechoic foetal colonic content with no other intestinal abnormality. This is a rare pattern, which to our knowledge, has never been correlated with a specific pathology. The accidental observation of a cystine kidney stone in an infant who presented with this sign during the prenatal period made it possible to diagnose this disease retrospectively in two other children. Copyright © 2006 John Wiley & Sons, Ltd.     

Rapid interphase analysis for prenatal diagnosis of translocation carriers using subtelomeric probes

Interphase fluorescence in situ hybridization (FISH) has become an accepted laboratory technique for the rapid and preliminary prenatal assessment of chromosome aneuploidy. The introduction of subtelomeric FISH probes now allows for the molecular–cytogenetic analysis of terminal chromosome rearrangements. In a prospective study, we examined the prenatal use of subtelomeric probes on interphase cells to rapidly detect the carrier status of a fetus when a parent carried a known reciprocal or Robertsonian chromosome translocation. Three of the cases were identified as being abnormal. All cases were confirmed by routine cytogenetic analysis. These findings clearly demonstrated the utility of this technique and these probes to rapidly and correctly identify balanced and unbalanced chromosome anomalies of a fetus that could result from parental translocations. Copyright © 2002 John Wiley & Sons, Ltd.     

交通系统智能决策的算法研究

遗传算法是近年来迅速发展起来的一种全新的随机搜索与优化算法，但由于其自身固有的缺陷，通常优化过程的收敛速度较慢，局部搜索能力不足，而且算法稳定性较差。而蚁群算法广泛应用在旅行商问题计算中，目前是较好的求解最短路由问题的算法之一。就其自身来说有很多优点，如正反馈性、鲁棒性和智能性，但是在寻优过程中容易陷入局部最佳的缺点。针对上述情况，将遗产算法与蚁群算法相结合，用于实际交通系统寻找最优路径的问题中，并定义了目标函数，以路径可靠性和路径长度为优化目标，寻找最合适的救灾路线。最后通过实际计算结果的对比验证，说明了该方法的有效性。