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Jos Luiz de Magalhes Rios Jos Laerte Boechat Adriana Gioda Celeste Yara dos Santos Francisco Radler de Aquino Neto Jos Roberto Lapa e Silva 《Environment international》2009,35(8):1136-1141
ObjectivesAn increasing number of complaints related to time spent in artificially ventilated buildings have been progressively reported and attributed, at least in part, to physical and chemical exposures in the office environment. The objective of this research was to investigate the association between the prevalence of work-related symptoms and the indoor air quality, comparing a sealed office building with a naturally ventilated one, considering, specially, the indoor concentration of TPM, TVOCs and the main individual VOCs.MethodsA cross-sectional study was performed to compare the prevalence of sick building syndrome (SBS) symptoms among 1736 office workers of a sealed office building and 950 of a non-sealed one, both in Rio de Janeiro's downtown. The prevalence of symptoms was obtained by a SBS standardized questionnaire. The IAQ of the buildings was evaluated through specific methods, to determine the temperature, humidity, particulate matter and volatile organic compound (VOC) concentrations.ResultsUpper airways and ophthalmic symptoms, tiredness and headache were highly prevalent in both buildings. Some symptoms were more prevalent in the sealed building: “eye dryness” 33.3% and 27.1% (p: 0.01); “runny nose” 37.3% and 31.3% (p: 0.03); “dry throat” 42% and 36% (p: 0.02); and “lethargy” 58.5% and 50.5% (p: 0.03) respectively. However, relative humidity and indoor total particulate matter (TPM) concentration as well as total volatile organic compounds (TVOCs) were paradoxically greater in the non-sealed building, in which aromatic compounds had higher concentration, especially benzene. The analysis between measured exposure levels and resulting symptoms showed no association among its prevalence and TPM, TVOCs, benzene or toluene concentration in none of the buildings.ConclusionsOther disregarded factors, like undetected VOCs, mites, molds and endotoxin concentrations, may be associated to the greater prevalence of symptoms in the sealed building. 相似文献
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This article examines the use of “radiophobia,” “Chernobyl syndrome,” “irrationality,” and other similar concepts in communications on nuclear issues. Historically, these terms have been used in two ways: to describe psychological effects among people affected by nuclear disasters such as Hiroshima or Chernobyl, and to explain the concerns of the unaffected lay public about radiation or nuclear power projects. The latter was actively used in the Soviet Union and in post-Soviet countries such as Belarus to rejects citizens’ complaints and to denounce the arguments of the anti-nuclear camp. This study argues that although the terms can legitimately be used in many situations, their use in communications about nuclear issues can be problematic. 相似文献
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C. Le Caignec C. Gicquel M. C. Gubler C. Guyot M. C. You A. Laurent M. Joubert N. Winer A. David J. M. Rival 《黑龙江环境通报》2004,24(3):165-168
Beckwith–Wiedemann syndrome (BWS) is an overgrowth syndrome associated with congenital malformations and tumour predisposition. BWS results from variable mutations or epigenetic modifications of imprinted genes in the 11p15 chromosomal region. We present a fetus with mild general overgrowth and bilateral enlarged echogenic kidneys with loss of the corticomedullary differentiation in which prenatal diagnosis of BWS was suspected. The rest of the fetal anatomy and the amniotic fluid volume appeared normal. After termination of the pregnancy, molecular analysis confirmed the diagnosis of BWS by showing an isolated hypermethylation of the H19 gene. Copyright © 2004 John Wiley & Sons, Ltd. 相似文献
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F. Kara N. Yesildaglar R. A. Tuncer N. Semerci N. Onat Y. Ç. Yilmazer T. Sipahi S. Erkaya 《黑龙江环境通报》2002,22(5):395-397
Ophthalmo-acromelic syndrome type Waardenburg is an extremely rare autosomal recessive syndrome comprising eye malformations ranging from true anophthalmia to mild microphthalmia with acromelic malformations. We report a case of ophthalmo-acromelic syndrome type Waardenburg diagnosed prenatally. Copyright © 2002 John Wiley & Sons, Ltd. 相似文献
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The agreement between predicted risks of Down syndrome and observed prevalence was investigated in a population of 11 847 singleton pregnancies screened by first trimester nuchal translucency at a single institution. Twenty-seven cases of Down syndrome were observed; 20 were detected prenatally by nuchal translucency and maternal age screening, three by other means and four postnatally. The screened women were grouped according to their predicted risk of having an affected pregnancy, and this was compared with the observed prevalence. A significant correlation between predicted and observed prevalences was noted, thus demonstrating that risk estimates for Down syndrome based on first trimester nuchal translucency screening are accurate. Copyright © 2002 John Wiley & Sons, Ltd. 相似文献