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91.
通过毒理学“大数据”,挖掘三丁基锡(TBT)潜在的生物影响信息,预测分析TBT暴露与人类相关疾病的关系.通过比较毒理组学数据库(CTD)搜集到488个和TBT具有相互作用的基因.基因相互作用网络图显示TP53拥有相关联基因最多,处于中心地位;其次是ESR1和FN1.CTD分析与TBT相关的疾病,发现前10类疾病分别是癌症、神经系统疾病、心血管疾病、泌尿生殖系统疾病(女)、消化系统疾病、代谢疾病、泌尿生殖系统疾病(男)、内分泌系统疾病、免疫系统疾病、呼吸道疾病.KEGG通路和DAVID基因功能注释分析,发现TBT不仅和代谢性疾病有较高的关联性,其相互作用基因在糖代谢途径上亦有较密集的基因功能注释.PASS的活性预测也发现TBT可能影响多种与糖代谢相关的酶生物活性.这提示TBT对糖代谢相关疾病的影响应引起人们的注意.  相似文献   
92.
刘家祥  陈全 《安全》2019,40(5):11-14
为提升企业的安全风险管控水平,以R化工厂的甲醇成品罐区为例,运用系统的危险源辨识方法对其设备、工艺过程、切罐、倒罐操作程序、生产作业活动等进行系统全面的危险源辨识,形成安全风险信息数据库。基于安全风险信息数据库,开发各种风险管控工具。利用信息化技术,构建安全风险管控信息系统,对企业实行动态化的安全管理。  相似文献   
93.
周俊红  唐桃  彭远春 《安全》2019,40(5):54-57
基于钻井现场安全监督在管控钻井作业风险中的重要性和当前钻井安全监督能力方面的缺陷,采用信息化手段,提出了钻井现场安全监督系统整体架构设计和数据库建设思路,介绍了系统功能和应用情况,结果表明:该系统能够显著提高钻井现场监督工作质量,实现钻井现场安全事故的有效控制。  相似文献   
94.
陈全  陈婷 《安全》2019,40(6):24-27
基于风险管理科学原理,以国内某铜冶炼企业为例,通过实地调查研究企业生产作业活动及安全管理现状,选取科学适用的风险辨识方法,系统全面的辨识企业生产过程安全风险,建立企业安全风险信息数据库,并且进行常态化的动态更新,保证企业安全风险信息与企业生产实际的契合。同时以风险信息数据库为依托,完善企业安全管理手段并开发新的安全风险管控手段,以实现安全风险信息数据库在企业安全管理的实际应用,避免或减少安全生产事故的发生。  相似文献   
95.
Objective: Prior research suggested that single-unit trucks are undercounted when using vehicle body codes in the Fatality Analysis Reporting System (FARS). This study explored the extent of the misclassification and undercounting problem for crashes in FARS and state crash databases.

Methods: Truck misclassifications for fatal crashes were explored by comparing the Trucks Involved in Fatal Accidents (TIFA) database with FARS. TIFA used vehicle identification numbers (VINs) and survey information to classify large trucks. This study used VINs to improve the accuracy of large truck classifications in state crash databases from 5 states (Delaware, Maryland, Minnesota, Nebraska, and Utah).

Results: The vehicle body type codes resulted in a 19% undercount of single-unit trucks in FARS and a 23% undercount of single-unit trucks in state databases. Tractor-trailers were misclassified less often. Misclassifications occurred most frequently among single-unit trucks in the weight classes of 10,001–14,000 pounds.

Conclusions: The amount of misclassification of large trucks is large enough to potentially affect federal and state decisions on traffic safety. Using information from VINs results in more complete and accurate counts of large trucks involved in crashes. The National Transportation Safety Board recommended actions to improve federal and state crash data.  相似文献   

96.
导弹环境适应性数据库开发构想   总被引:1,自引:0,他引:1  
根据导弹设计师急需获取环境适应性信息指导相关工作的开展,但由于种种原因无从获取,通过构想,从现状、开发目标、可行性分析、需求分析、信息构成、组织及信息共享方式等角度对数据库开发所涉及的要素进行了分析,为导弹装备环境适应性数据库开发工作明确了思路,奠定了基础。  相似文献   
97.
广州地区SO42-、NO3-、NH4+与相关气体污染特征研究   总被引:7,自引:2,他引:5  
本文获得了2009年12月1日至2011年12月31日广州二次无机离子(SO2-4、NO-3、NH+4)及相关反应性气体(NOx/SO2/HNO2/HNO3等)的小时浓度数据,并分析了其污染特征.研究结果表明:PM2.5的浓度季节变化特征为冬秋春夏,SO2-4的浓度季节变化特征为秋冬春夏,NH+4的为冬秋春夏,NO-3则为冬春秋夏,SO2-4、NO-3和NH+4之和占PM2.5的比重大小为秋夏春冬;硫氧化率(SOR)均大于0.1,秋冬季节的值高于春夏季节,与SO2-4的浓度变化趋势一致;氮氧化率(NOR)日变化呈单峰形式,最大值出现在06时,最小值出现在14时,春冬季节的值高于夏秋季节,与NO-3的浓度变化趋势一致;广州地区NH3/NH+4除10—12月外,其月均值均大于1;在典型过程中,SO2-4、NO-3、NH+4、SOR、NOR和NH3/NH+4与能见度的变化都存在较好的对应关系,说明广州地区低能见度与二次离子(SO2-4、NO-3、NH+4)的生成有关.  相似文献   
98.
冯梅 《云南环境科学》2006,25(Z2):82-84
应用灰色关联分析评价法和叠加综合指数模型,分别对玉溪"三湖"丰水期、枯水期水质现状进行了评价.  相似文献   
99.

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Goal Scope and Background. The European Directive on Energy Performance of Buildings which came into force 16 December 2002 will be implemented in the legislation of Member States by 4 January 2006. In addition to the aim of improving the overall energy efficiency of new buildings, large existing buildings will become a target for improvement, as soon as they undergo significant renovation. The building sector is responsible for about 40% of Europe's total end energy consumption and hence this Directive is an important step for the European Union in order that it should reach the level of saving required by the Kyoto Agreement. In this the EU is committed to reduce CO2 emissions relative to the base year of 1990 by 8 per cent, by 2010. But what will be the impact of the new Directive, how large could be the impacts of extending the obligation for energy efficiency retrofitting towards smaller buildings? Can improvement of the insulation offset or reduce the growing energy consumption from the increasing installation of cooling installations? EURIMA, the European Insulation Manufacturers Association and EuroACE, the European Alliance of Companies for Energy Efficiency in Buildings, asked Ecofys to address these questions.

Methods

The effect of the EPB Directive on the emissions associated with the heating energy consumption of the total EU 15 building stock has been examined in a model calculation, using the Built Environment Analysis Model (BEAM), which was developed by Ecofys to investigate energy saving measures in the building stock. The great complexity of the EU-15 building stock had to be simplified by examining five standard buildings with eight insulation standards, which are assigned to building age and renovation status. Furthermore, three climatic regions (cold, moderate, warm) were distinguished for the calculation of the heating energy demand. This gave a basic 210 building types for which the heating energy demand and CO2 emissions from heating were calculated according to the principles of the European Norm EN 832.

Results and Discussion

The model calculations demonstrates that the main contributor to the total heating related CO2 emissions of 725 Mt/a from the EU building stock in 2002 is the residential sector (77%) while the remaining 23% originates from non-residential buildings. In the residential sector, single-family houses represent the largest group responsible for 60% of the total CO2 emissions equivalent to 435 Mt/a.

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- The technical potential: If all retrofit measures in the scope of the Directive were realised immediately for the complete residential and non-residential building stock the overall CO2 emission savings would add up to 82 Mt/a. An additional saving potential compared to the Directive of 69 Mt/a would be created if the scope of the Directive was extended to cover retrofit measures in multi-family dwellings (200-1000m2) and non-residential buildings smaller than 1000m2 used floor space. In addition including the large group of single-family dwellings would lead to a potential for additional CO2 emission reductions compared to the Directive of 316 Mt/a.

-

- Temporal mobilization of the potential: Calculations based on the building stock as it develops over time with average retrofit rates demonstrated that regulations introduced following the EPB Directive result in a CO2 emissions decrease of 34 Mt/a by the year 2010 compared to the business as usual scenario. Extending the scope of the EPB Directive to all residential buildings (including single and multi-family dwellings), the CO2 emission savings potential over the 'business as usual' scenario could be doubled to 69 Mt/a in the year 2010. This creates an additional saving potential compared to the Directive of 36 Mt/a.

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- Cooling demand: The analysis demonstrated that in warm climatic zones the cooling demand can be reduced drastically by a combination of lowering the internal heat loads and by improved insulation. With the reduction of the heat loads to a moderate level the cooling demand, e.g. of a terraced house located in Madrid, can be reduced by an additional 85% if the insulation level is improved appropriately.

Conclusions

This study demonstrates that the European Directive on Energy Performance of Buildings will have a significant impact on the CO2 emissions of the European building stock. The main saving potential lies in insulation of the existing building stock. Beyond this, CO2 emissions could, however, be greatly reduced if the scope of the Directive were to be extended to include retrofit of smaller buildings.

Recommendation and Perspective

The reductions should be seen in relation to the remaining gap of 190 Mt CO2 eq. per annum between the current emission levels of EU-15 and the target under the Kyoto-Protocol for the year 2010. The energy and industrial sector will probably contribute only a fraction of this reduction via the newly established EU emissions trading scheme and connected projects under the flexible mechanism. In addition, the traffic sector is likely to continue its growth path leading to a widening of the gap. Thus, there is likely to be considerable pressure on the EU building sector to contribute to the EU climate targets beyond what will be achieved by means of the current EPB Directive. Legislators on the EU and national level are therefore advised to take accelerated actions to tap the very significant emission reduction potentials available in the EU building stock.  相似文献   
100.
River basins provide a wide range of ecosystem services important for human well-being. Ecosystem functions and their value to humans have been thoroughly studied. However, the role of governance characteristics for the sustainable management of ecosystem services has been largely ignored up to now. To close this gap, this article introduces the latest modifications to a database building on the Management and Transition Framework (MTF) that serve to study the relationship between water governance and management systems and their performance with regard to impacts on ecosystem services. This comprehensive approach facilitates structured data collection and representation in order to analyze single case studies or compare case studies regarding the governance and management of water resources and associated ecosystem services. It allows the user to investigate whether certain water governance characteristics, such as stakeholder involvement or vertical integration of governance levels, are associated with a change in the management of ecosystem services or a measurable change in their state. A simplified case from South Africa shows how the database modifications allow addressing links between governance and management processes on the one side and ecosystem services and the way they are handled on the other side. Applying the MTF database leads to evidence-based insights into best practices as well as failed management approaches and interventions. This in turn provides knowledge that can be transferred from science to practice supporting sustainable governance of ecosystem services.  相似文献   
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