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231.
Chorionic villus sampling (CVS) was performed in 12 pregnant women (9–25 gestational weeks) with ultrasonographic evidence of missed abortion. An ultrasonographically guided transabdominal (eight cases) or transcervical (four cases) approach was used. Fetal karyo-typing was successful in all cases; in five, chromosomal aberrations were found and in seven, chromosome analyses revealed normal karyotypes. Tissue culture for fetal karyotyping was successful in only 72.5 per cent of 40 live pregnancies which were electively interrupted because of abnormal ultrasonographic findings or an abnormal fetal karyotype, and in 57 per cent of seven missed abortions. CVS is suggested as a feasible and effective method for fetal karyotyping in missed abortions and it seems to be superior to post-abortion tissue culture. 相似文献
232.
A total of 1068 patients were examined by ultrasound to ensure normality of pregnancy and followed prospectively from booking until 28 weeks. The spontaneous miscarriage rate was 2.7 per cent occuring within the first 16 weeks. Threatened miscarriage was associated with a 38 per cent fetal loss. Miscarriage was less likely as pregnancy advanced. The reduction in subsequent miscarriage rate before 11 weeks and from 11 weeks onwards is statistically significant (p<0.001). Gravidity, maternal age and a history of previous fetal loss did not contribute significantly to the miscarriage rate. Patients with a history of fetal loss were more likely to experience a threatened miscarriage. The relevance of these findings to chorion villus sampling is discussed. 相似文献
233.
Dr. D. F. Callen H. Fernandez Y. J. Hull J. M. Svigos H. M. Chambers G. R. Sutherland 《黑龙江环境通报》1991,11(7):437-442
A predominantly triploid 69,XXY placenta was found associated with a normal 46,XX infant. Therefore, a triploid placenta is apparently capable of supporting normal fetal development. The chromosome and pathological results support the conclusion that the triploid placenta originates from a ‘vanishing twin’ pregnancy. This case is unusual in that persistence of the placenta from the vanished twin has virtually replaced most of the normal placenta. 相似文献
234.
Meena Upadhyaya Alan Fryer Graham Foat Denise Robinson Oliver Quarrell Adrian Roberts P. S. Harper 《黑龙江环境通报》1990,10(9):593-603
Chorionic villi were sampled from 125 women who requested prenatal diagnosis, either for genetic disorders or because of advanced maternal age. Of these, 105 samples were obtained by the transcervical route and 20 were obtained by the transabdominal approach. The sampling success rate was 97 per cent (122/125). The mean maternal age of the patients was 31 years (range 17–44) and the mean gestational age at which the chorionic villus sampling was performed was 10 weeks (range 7–13 weeks). Seventy-four of these diagnoses involved the use of DNA markers. The minimal size of the sample used for DNA diagnosis was 5 mg. Maternal contamination was detected in two samples. A diagnosis was provided on all but two samples. The fetal loss rate was high initially but fell to 1·9 per cent in 1988. 相似文献
235.
利用采样和分析全程质量控制程序(SAX),对于吉林省内7个天然水体底质中Mn元素的采样和分析过程进行了质量控制(QC)实例研究.实验采用了平行采样平行分析的设计方案,并进行了空白实验、重复测定和加标回收率的测定.然后利用稳健方差分析(Robust ANOVA)计算了采样分析全过程中的地理方差、采样方差和分析方差,并对整个质控过程按照适目的性原则进行了评价.通过本文的研究以及其他工作成果,可知评价中采用的比例限值标准在一般意义下的SAX过程中是行之有效的.但是,也应注意到该限值标准不是绝对的,在具体的实验设计中需要考虑多方面因素. 相似文献
236.
Risk assessment of amniocentesis between 11 and 15 weeks: Comparison to later amniocentesis controls
We studied 693 consecutive early amniocenteses (prior to 15 weeks) and found a spontaneous abortion rate to 28 weeks' gestation of 1·5 per cent. A control group of women having standard amniocentesis (15–20 weeks) experienced a 0·6 per cent fetal loss in the same period. There were no other apparent differences between the two groups. Early amniocentesis results are generally available 4–6 weeks before standard amniocentesis and 1–3 weeks after chorionic villus sampling (CVS). Alpha-fetoprotein (AFP) can be accurately assayed in 11- to 15-week amniotic fluid samples but additional studies are necessary to determine the accuracy of neural tube defect (NTD) detection. Including the present study, over 5800 early amniocenteses have been reported and the results suggest that this is a relatively safe prenatal diagnostic test and an alternative to CVS and later amniocentesis. 相似文献
237.
A case of 46,XX/47,XXY mosaicism was diagnosed at 22 gestational weeks by amniocentesis and fetal blood sampling. After genetic counselling, the couple elected to have the pregnancy terminated. Culture of the fetal skin and both gonads confirmed the prenatal diagnosis. In external appearance, the abortus had no remarkable findings except hypospadia. Histology of both gonads showed testicular tissue without evidence of ovarian components. 相似文献
238.
在监测准备过程中,按照明确监测内容,收集现场资料,制定监测方案,监测人员落实及培训,监测仪器材料准备;在现场监测过程中,按照到达监测现场安顿,现场监测前评估,开始监测采样,监测资料数据收集,样品保存与运输;在监测结束过程中,按照监测结束评估,监测现场恢复,样品及资料交接,返回前最后检查,监测设备交接,进行监测总结等现场监测的基本过程,对环境监测中现场工作流程进行了解释和分析. 相似文献
239.
JOSÉ DANIEL ANADÓN† RÉS GIMÉNEZ RUBÉN BALLESTAR IRENE PÉREZ 《Conservation biology》2009,23(3):617-625
Abstract: The use of local ecological knowledge (LEK) has been advocated for biodiversity monitoring and management. To date, however, it has been underused in studying wild populations of animals and, particularly, in obtaining quantitative abundance estimates. We evaluated LEK as a tool for collecting extensive data on local animal abundance and population trends. We interviewed shepherds in southeastern Spain, asking them to estimate the local abundance of the terrestrial tortoise Testudo graeca . We quantified reliability of abundance estimates derived from interviews by comparing them with those obtained from standard field-sampling protocols (distance sampling). We also explored the complementarity of these 2 approaches. LEK provided high-quality and low-cost information about both distribution and abundance of T. graeca . Interviews with shepherds yielded abundance estimates in a much wider range than linear transects, which only detected the species in the upper two-thirds of its abundance range. Abundance estimates from both methodologies showed a close relationship. Analysis of confidence intervals indicated local knowledge could be used to estimate mean local abundances and to detect mean population trends. A cost analysis determined that the information derived from LEK was 100 times cheaper than that obtained through linear-transect surveys. Our results should further the use of LEK as a standard tool for sampling the quantitative abundance of a great variety of taxa, particularly when population densities are low and traditional sampling methods are expensive or difficult to implement. 相似文献
240.
K.M.S. Sundaram 《Journal of environmental science and health. Part. B》2013,48(4-5):409-426
Abstract Fenitrothion and aminocarb formulations were aerially sprayed over mixed coniferous forests near Fredericton and Bathurst, New Brunswick, Canada. Insecticide concentrations inside the spray blocks were measured at intervals of time by trapping the airborne toxicants in a fritted‐glass bubbler containing dimethylformamide (DMF). The residues in DMF were analysed by gas chromatography. Concentrations of the insecticides in the air sampled decreased rapidly with time from peak levels of 1997 ng/m3 (fenitrothion) and 1201 ng/m3 (aminocarb). Concentrations of the two insecticides in the air samplers were dependent upon the nature of the chemicals, type of formulation used, spray timings and other environmental factors. 相似文献