The 48,XXYY syndrome: A case detected by maternal serum alpha-fetoprotein screening

A 17-year-old woman was referred for amniocentesis due to a low maternal serum alpha-fetoprotein (AFP) concentration in a voluntary screening test. The fetal karyotype was 48,XXYY, and the pregnancy was terminated. Autopsy of the fetus disclosed agenesis of the corpus callosum and unusual facial features.     

关于环境教育的思考

目前，我国专业环境教育毕业生供需基本平衡，但有专业设置过繁之弊；中小学环境教育处实验阶段，尚未普及；社会环境教育滞后则多由经济和文化落后所致。必须针对存在问题，借鉴国外成功经验，办好中国的环境教育。     

Prenatal screening and diagnosis of neural tube defects in England and Wales in 1985

A survey was carried out to determine the effect of prenatal screening and therapeutic abortion on births in 1985 with anencephaly and spina bifida in England and Wales. Maternal serum alpha-fetoprotein tests were done on 399 288 women (60 per cent of pregnant women): 4 per cent were reported as being screen-positive and 1 per cent had an amniocentesis. An estimated 534 pregnancies associated with anencephaly were terminated and an estimated 445 pregnancies associated with spina bifida (but without anencephaly) were terminated. Most (63 per cent) of the anencephalic pregnancies were first suspected from an ultrasound examination; 57 per cent of the spina bifida pregnancies were first suspected from a positive maternal serum alpha-fetoprotein test, 35 per cent by ultrasound, and the remaining 8 per cent by other means. The birth prevalence of anencephaly declined by 94 per cent between 1964–1972 and 1985, but when the terminations of pregnancy on account of having a fetus with anencephaly are added to the births the decline in prevalence was only 50 per cent. The birth prevalence of spina bifida declined by 68 per cent over the same period but when the terminations were added to the births the decline in prevalence was only 32 per cent. Among births with anencephaly 66 per cent had had no screening or diagnostic tests in early pregnancy, but in those that did nearly all were positive–usually in twin pregnancies where one fetus was affected but not the other. Among births with spina bifida, 48 per cent had no tests and in those that did the results were mainly negative. We conclude that in order to monitor adequately the national screening programme for anencephaly and spina bifida a special neural tube defects register should be formed.     

化学降阻剂在山地环境中的应用研究

把山地环境划分为4种类型,并对各自的特点进行了分析.从导电机理和降阻机理两个方面分析了化学降阻剂的降阻功能,根据不同地质条件讨论了化学降阻剂的合理选择,并对化学降阻剂的应用方法和技术进行了研究,为山区防雷提供一定的参考价值.     

企业开展污水回用工作存在的主要问题及对策

发挥政府职能,转变用水观念,拓展筹资方式,开发回用水市场,降低成本等是企业解决污水回用问题的有效对策和措施.文章对泰皇岛港务集团公司污水回用工作的成功实践进行了分析,该实例表明企业完全可以开展污水回用工作,工程社会、经济、环境效益明显,实际运行经验可供其他企业借鉴.     

膜生物反应器技术的研究和应用展望

膜生物反应器是将膜分离技术与生物上结合而开发的新型系统，该文就膜生物反应器的特征、研究现状、不同形式反应器的技术参数与处理效果等。进行了综述、由于膜生物反应器具有明显的优点，故愈来愈受到人们的重视、成为研究的热点之一。膜生物反应器的研究和范围不断拓宽，有的已进入污水处理实用阶段，建议今后在开发适合于分离的特种膜方面，在组件形式，操作条件，清洗方式等对膜通量的影响方面，以及生物作用与膜分离工艺的相互     

陡坡地灌桑垄槽栽培研究

陡坡地灌桑垄槽栽培研究结果,免除土壤侵蚀的危害,其５０ｃｍ、１００ｃｍ土壤中,比对照区持水量高１０.２０％～３３.６７％、８.２７％～６５.３７％,含全氮率为对照的９０％,含全磷率高２.９％、２６.２％,含全钾率高３.１８％、８.０１％,而水解氮均为对照的６１.５％,速效磷高较对照３９.０２％、９７.７２％,速效钾为对照的９１.４８％、９２.５４％。公顷产桑叶量和蚕茧量均较对照高５～１０倍,经济效益较对照高１１.８８倍。     

Attitudes to prenatal screening,diagnosis and research among pregnant women who accept or decline an alpha-fetoprotein test

The aim of the study was to describe the opinion of pregnant women who had accepted or declined an alpha-fetoprotein (AFP) test, not only on AFP screening in general, but also on whether every pregnant woman should be offered amniocentesis (AC)/chorionic villus sampling (CVS) and an ultrasound scan for fetal malformations. An additional aim was to describe pregnant women's attitudes concerning continued research in the prenatal field. The study was performed as a questionnaire study in two regions over a 1-year period from 1 October 1988 to 30 September 1989. Results are based on answers from 3331 women who had taken an AFP test and 336 women who had declined the offer of a test. A total of 79 per cent of the women thought that an AFP test, 70 per cent that an ultrasound scan for fetal malformations, and 26 per cent that AC or CVS should be offered to all pregnant women. Fifty-nine per cent of the women were positive towards continued research in the prenatal field. Women who had had an AFP test were generally much more positive towards screening and research than women who had declined, who were generally against. Women who had left school without a high school degree were on average more positive towards the screening issues than women who had this degree. In conclusion, the results obtained in this study strongly suggest that women's attitudes are very dependent on how the prenatal screening programme is already organized in their local area.     

Enhanced twin pregnancy detection within an open neural tube defect and down syndrome screening protocol using free-beta hCG and AFP

We have applied our multimarker approach of maternal serum alpha-fetoprotein (AFP) and free-beta human chorionic gonadotropin (hCG) for Down syndrome screening to multiple gestations to assess its efficacy for improved detection of twin and triplet pregnancies. This study matched 225 cases of twin pregnancy and 39 cases of triplet pregnancy each with ten singleton pregnancies based on gestational week, race, time to receive sample, time of year of sample, and geographical area. The ratios of the MOM for each group at the tenth, 50th, and 90th percentiles were compared by the Wilcoxon test. Risks for twins were calculated using Bayes' rule, the age-related incidence of twins, and the levels of AFP and free-beta hCG. The tenth, 50th, and 90th percentiles of free-beta hCG MOMs in twin and triplet cases were 0.85, 1.99, and 4.51, and 1.38, 2.78, and 4.07, respectively. For AFP, the MOMs at these percentiles were 1.26, 1.91, and 2.99, and 2.02, 2.68, and 5.30, respectively. The twin and triplet distributions for each marker were statistically significantly different from the singleton distributions (P<0.0001) and from each other (P=0.0012). At a twin risk cut-off of 1 in 50, 77.4 per cent of all twin gestations can be detected in a second-trimester AFP and free-beta hCG screening protocol with 5.1 per cent of singleton pregnancies falsely identified as at risk for twins. Our dual marker protocol for mid-trimester pregnancy screening combining AFP and free-beta hCG can identify over 77 per cent of twin pregnancies in women less than 35 years of age. This benefit may contribute to an improved outcome of pregnancy by early detection of multiple gestation.     

黄土高原砖窑沟试验区土壤资源与改良利用途径

本文以田间试验、定位观测和野外调查为依据，系统地研究了位于晋西北黄土丘陵区的砖窑沟试验区土壤资源特点及采用改良利用措施后的效果。结果表明，试验区土壤类型多，肥力低。低产原因主要是：土质过砂，有机质含量低，气候多灾，侵蚀严重，经济贫困。通过修建水平梯田，实施快速培肥技术；实行以有机肥与氮肥为主的优化施肥方案；蓄水保水，合理用水，提高水分生产效率等一系列措施，有效地提高了土壤肥力，改善了环境条件。根据科学试验和生产实践，提出了在该地区具有普遍意义的改土培肥途径。