Profiling the antibiotic resistome in soils between pristine and human-affected sites on the Tibetan Plateau

With increasing pressure from anthropogenic activity in pristine environments, the comprehensive profiling of antibiotic resistance genes(ARGs) is essential to evaluate the potential risks from human-induced antibiotic resistance in these under-studied places. Here, we characterized the microbial resistome in relatively pristine soil samples collected from four distinct habitats on the Tibetan Plateau, using a Smart chip based high-throughput q PCR approach. We compared these to soils from the s...     

基于集对分析-吸收马尔可夫链的铁路移动通信系统安全动态评估*

为了更有效地评估和防范铁路数字移动通信系统（GSM-R）的安全风险，针对未考虑系统不同时期系统风险状况不同、研究多局限于静态评估的不足，提出基于马尔可夫链的风险指数量化计算方法，构建基于集对分析-吸收马尔可夫链的铁路数字移动通信系统（GSM-R）风险评估模型。首先使用吸收马尔可夫链对通信系统风险进行定量计算，运用集对分析关联度的同一性、差异性和矛盾性动态分析通信系统安全风险的趋势，通过结合马尔可夫链计算下一阶段的关联度以获得通信系统最终安全风险评估结果，选取通信系统6个时间段数据进行分析，并进行验证。结果表明:本文评估方法能实现铁路数字移动通信系统（GSM-R）安全风险的全面动态评估，验证通信系统安全风险动态评估模型的科学性、有效性和可行性。