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811.
Marta Staniszewsk Iga Koniecko Lucyna Falkowsk Dorota Bursk Joanna Kie?czewska 《环境科学学报(英文版)》2016,28(3):24-32
This study was derived from field investigations to assess bisphenol A (BPA) concentrations in the sea and river sediments of the Gulf of Gdansk. Black carbon (BC) and total organic carbon (TOC) were identified as influencing factors on the accumulation. As a result of the transportation of BC with organic matter via rivers into the Gulf of Gdansk, the highest mean concentrations (11.26 ng BPA/(g dry weight (dw))), were determined in the sediments of river estuaries. Sediments in coastal stations were characterized by the lowest mean concentrations (5.73 ng BPA/(g dw)). TOC content below 0.1% determined the sorption of BPA on BC particles in sediments, and statistically significant correlation between the concentration of BPA and the BC/TOC ratio was found in these cases. In addition, dependency between the concentration of BPA and the content of BC was discovered in sediments where the BC/TOC ratio was > 0.33. 相似文献
812.
Laziyan Mahemuti Qixuan Chen Melanie C. Coughlan Min Zhang Maria Florian Ryan J. Mailloux Xu-Liang Cao Kylie A. Scoggan William G. Willmore Xiaolei Jin 《环境科学学报(英文版)》2016,28(10):11-23
Bisphenol A(BPA) has been shown to exert biological effects through estrogen receptor(ER)-dependent and ER-independent mechanisms. Recent studies suggest that prenatal exposure to BPA may increase the risk of childhood asthma. To investigate the underlying mechanisms in the actions of BPA, human fetal lung fibroblasts(h FLFs) were exposed to varying doses of BPA in culture for 24 hr. Effects of BPA on localization and uptake of BPA,cell viability, release of immune and developmental modulators, cellular localization and expression of ERα, ERβ and G-protein coupled estrogen receptor 30(GPR30), and effects of ERs antagonists on BPA-induced changes in endothelin-1(ET-1) release were examined.BPA at 0.01–100 μmol/L caused no changes in cell viability after 24 hr of exposure. h FLFs expresses all three ERs. BPA had no effects on either cellular distribution or protein expression of ERα, however, at 100 μmol/L(or 23 μmol/L intracellular BPA) increased ERβprotein levels in the cytoplasmic fractions and GPR 30 protein levels in the nuclear fractions.These paralleled with increased release of growth differentiation factor-15, decreased phosphorylation of nuclear factor kappa B p65 at serine 536, and decreased release of ET-1,interleukin-6, and interferon gamma-induced protein 10. ERs antagonists had no effects on BPA-induced decrease in ET-1 release. These data suggest that BPA at 100 μmol/L altered the release of immune and developmental modulators in h FLFs, which may negatively influence fetal lung development, maturation, and susceptibility to environmental stressors, although the role of BPA in childhood asthma remains to be confirmed in in vivo studies. 相似文献
813.
正Bisphenol A(BPA,2,2-bis(4-hydroxyphenyl)propane;CAS#80-05-7)is a highly produced industrial chemical,with an estimated four billion kilograms produced worldwide each year(reviewed in Vandenberg et al.,2010).BPA serves as a monomer in the manufacture of polycarbonate,a hard,clear plastic.Polycarbonate plastics are used in many consumer products,such as reusable water bottles.BPA is also widely used to make epoxy resins,which are used as coating on the inside of some 相似文献
814.
近年来,随着普通高等学校的扩招,学校噪声污染有加剧的趋势,校园噪声问题成为学者关注的热点之一.以商洛学院校本部为例,采用功能区实地布点监测法,收集了商洛学院11个监测点2015年3-4月11天的监测数据,利用等效连续A声级和噪声污染指数法进行噪声污染分析.结果表明:校园整体噪声污染严重,超标率达88.6%,噪声污染空间上集中于教学区的一号教学楼,时间上周内工作日较严重.噪声污染的主要原因是校内外的交通噪声和建筑施工. 相似文献
815.
用A2/O新工艺处理焦化废水 总被引:7,自引:0,他引:7
介绍了充分利用旧有污水处理设施进行A^2/O法工艺技术改造的可行性,指出A^2/O工艺是今后焦化厂废水治理的发展方向。 相似文献
816.
817.
诺氟沙星对阿部鲻鰕鯱Ⅰ相、Ⅱ相酶活性及CYP1A1和P-gpmRNA表达影响 总被引:1,自引:1,他引:0
通过饲料暴露的方式研究了抗生素诺氟沙星(Norfloxacin,NFLX)对阿部鲻鰕鯱(Mugilogobius abei)Ⅰ相、Ⅱ相代谢酶活性以及CYP1A1和P-糖蛋白(P-gp) mRNA表达的影响。结果表明随着暴露时间的延长,NFLX对阿部鲻鰕鯱肝脏Ⅰ相代谢酶APND、 ERND均表现出先诱导后抑制的作用。24 h时NFLX的暴露浓度为20 μg?g-1对Ⅰ代谢酶APND和ERND的诱导达到最大值。当暴露时间达到168 h, APND和ERND均受到极显著抑制。Ⅱ相代谢酶GST和MDA在72 h受到最大诱导,经过168 h暴露后,GST活性逐渐恢复到正常水平,而MDA含量在50 μg?g-1浓度组仍然维持较高水平。CYP1A1和P-gp mRNA表达量随着暴露时间的延长而增加,168 h达到最大。APND、 ERND、GST、 MDA、CYP1A1 mRNA和P-gp mRNA响应敏感,适合作为NFLX暴露的生物标记物。
关键词:诺氟沙星;阿部鲻鰕鯱;肝脏酶活;CYP1A1;P-gp 相似文献
818.
某烷基苯厂F-101A加热炉炉管爆炸事故分析 总被引:1,自引:0,他引:1
本文针对某烷基苯厂F-101A加热炉炉管爆炸事故原因进行了深入分析,根据该起爆炸事故的伤亡情况、事故经济损失、事故现场建(构)筑物损害情况,应用蒸气云爆炸模型对该爆炸事故后果严重度进行了计算分析,计算结果与爆炸现场基本吻合,能比较客观地反映爆炸事故实际情况,可为该类事故原因分析提供借鉴. 相似文献
819.
采用不主动排泥的运行模式,在相同污泥负荷条件下,对比研究了膜-生物反应器(MBR)与传统活性污泥反应器(CASR)对两种典型内分泌干扰物--双酚A(BPA)与壬基酚聚氧乙烯醚(NPnEO,n=1~4)的去除效果.结果表明,在BPA-污泥负荷与NPnEO-污泥负荷分别为0.046~10.2 g·kg-1·d-1与0.097-0.701 g·kg-1·d-1的范围内,MBR与CASR均能有效去除这2种内分泌干扰物.随着运行时间的延长,污泥对目标物质的去除能力逐渐加强;相比CASB,MBR对目标物质的去除更强且稳定.在获得相同的出水目标物质浓度条件下,MBR可以耐受更高的容积负荷.2种内分泌干扰物的投加对MBR和CASR的COD和NH4-N的去除均没有明显影响. 相似文献
820.
An experimental study of the low-temperature and low-pressure autoignition of Jet A and surrogate fuels was conducted using the ASTM-E659 standardized test method. Two surrogate fuels (Aachen and JI mixtures), their individual components and two batches (POSF-4658 and POSF-10325) of standardized Jet A were tested using the ASTM-E659 method for a range of fuel concentrations and temperatures. The ignition behaviors were categorized into four distinct ignition modes. The individual hydrocarbon components had a wide range of ignition behaviors and minimum autoignition temperatures (AIT) values depending on the molecular structure. The two Jet A batches showed similar ignition behavior with measured AITs of 229 ±3°C and 225 ±3°C respectively. Both surrogates exhibited similar ignition behavior to Jet A with comparable AITs of 219 ±3.1°C (Aachen) and 228 ±3°C (JI) with the JI mixture proving to be a more suitable surrogate to Jet A in the low-temperature thermal ignition regime. 相似文献