苦碟子联合华佗再造丸治疗脑梗死疗效观察

探讨苦碟子联合华佗再造丸治疗脑梗死的临床疗效安全性．将150例脑梗死的病人（头颅CT证实）随机分成治疗组和对照组,治疗组为74例,对照组为76例．对照组采用常规治疗,治疗组在对照组的基础上给予华佗再造丸加苦碟子治疗．两组均给予阿司匹林和脑保护剂．治疗两周即一个疗程后观察两组临床疗效和药物反应．随访1年,2组复发率被统计．治疗组有效率为84．4％,对照组有效率为57％．两组比较疗效差异有统计学意义．1年后脑梗死复发率治疗组为9．49％,对照组为21．05％．不良反应治疗组5例出现头晕,对照组4例出现腹胀,均未影响疗效．苦碟子联合华佗再造丸能改善脑梗死的治疗效果且耐受性好．表2,参5．     

缺血性脑卒中危险因素的研究

探讨缺血性脑卒中发病的危险因素方法用1：1配对病例对照研究,收集病例和对照各100例,用缺血性脑卒中流行病学调查表进行调查,内容包括：一般情况、生活方式、既往病史、脑血管病家族史、体格检查、血脂、血糖用单因素和多因素条件logistic分析方法分析结果;单因素分析显示缺血性脑卒中组的血清总胆固醇、甘油三脂、低密度脂蛋白胆固醇、血糖、吸烟、饮酒、高血压、糖尿病、心脏病、脑血管病家族史与缺血性脑卒中的发病有关条件Logistic回归分析显示吸烟、高血压、心脏病是缺血性脑卒中的危险因素结论：吸烟、高血压、心脏病是缺血性脑卒中的危险因素．表5,参10．     

Mild fetal cerebral ventriculomegaly as a prenatal sonographic marker for Kartagener syndrome

Primary ciliary dyskinesia (PCD), also referred to as immotile-cilia syndrome or Kartagener syndrome, is a group of genetic disorders caused by defective cilia leading to chronic sinupulmonary infection, situs inversus and reduced fertility. Some PCD patients also have cerebral ventriculomegaly or hydrocephalus. We report here two fetuses and one newborn with mild cerebral ventriculomegaly and a suspected and/or confirmed diagnosis of PCD. These cases demonstrate that mild fetal cerebral ventriculomegaly can be a prenatal sonographic marker of PCD, certainly in fetuses with situs inversus or a history of a previous sib with PCD. Copyright © 2003 John Wiley & Sons, Ltd.     

Contribution of fetal cerebral MRI for diagnosis of structural anomalies

More than 20 years after its introduction, magnetic resonance imaging (MRI) is now considered a useful complementary tool in the imaging work-up of fetal brain structural anomalies, but its real contribution in neuro-fetal imaging is still controversial. Our purpose is to present an overview of the most valuable indications of fetal cerebral MRI in current practice as guided by dedicated ultrasound analysis. On the basis of a review of the literature and our personal experience, we underline herein the real complementarities between these two techniques in different clinical or imaging settings and show how MRI adds significant information compared with ultrasound, especially in the late second and third trimesters. We assess the interest of using MRI from a technical point of view (complete and extensive anatomical analysis, analysis of developmental and pathological processes) and from a practical point of view in different imaging and clinical settings. Copyright © 2009 John Wiley & Sons, Ltd.     

Prenatal ultrasonographic diagnosis of fetal cerebral ventriculitis associated with asymptomatic maternal cytomegalovirus infection

Cytomegalovirus is the most common cause of congenital viral infection. In utero infection is usually suspected in patients with growth-retarded fetuses or when maternal illness precipitates serological investigations. A case is presented where routine ultrasound examination at 30 weeks' gestation in an asymptomatic patient demonstrated mild fetal ventriculomegaly. Transvaginal ultrasound enabled the visualization of intraventricular adhesions and small periventricular cysts. The suspected diagnosis of in utero cytomegalovirus infection was confirmed by the presence of IgM antibodies in fetal blood and subsequently by isolation of the virus from the infant's urine. The presence of mild fetal ventriculomegaly should prompt transvaginal brain imaging.