基于政府视角的人力资本投资分析

本文首先分析了政府在人力资本投资中的作用，然后从实现政府工作目标的角度探讨了人力资本投资的重要意义，最后提出增加人力资本投资的政策性建议．     

Detection of trisomy 21 by quantitative fluorescent–polymerase chain reaction in uncultured amniocytes

Prenatal diagnosis of fetal trisomy 21 is usually performed by cytogenetic analysis. This requires lengthy laboratory procedures, high costs and is unsuitable for large-scale screening of pregnant women. Today, trisomy 21 can be rapidly diagnosed within 24 h by molecular analysis of uncultured fetal cells using the semi-quantification of fluorescent PCR products from short tandem repeat (STR) polymorphic markers. The aim of our study was to test a chromosome quantification method on the basis of the analysis of fluorescent PCR products derived from non-polymorphic target genes. Co-amplification of a portion of DSCR1 (Down syndrome Critical Region 1) and the reference gene, CFTR (cystic fibrosis transmembrane regulator) enabled molecular detection of trisomy 21. Our method was successfully tested on a total of 154 amniotic fluids in a blind prospective study. Calculation of the DSCR1/CFTR ratio allowed us to distinguish between 152 normal amniotic fluids (mean ratio 0.99) and 2 amniotic fluids presenting a trisomy 21 status (DSCR1/CFTR ratio of 1.53 and 1.61, respectively). The results obtained by conventional cytogenetic analysis and our quantitative PCR method were concordant in every case. Our gene-based fluorescent PCR approach represents an alternative molecular method for rapid and reliable detection of trisomy 21, which can be helpful in the prenatal diagnosis of women at high risk of fetal trisomy 21. Copyright © 2003 John Wiley & Sons, Ltd.     

用自旋标记方法研究环境诱变剂对健康人红细胞膜动态性质的影响

健康人的完整血红细胞膜用脂肪酸自旋标记物Ⅰ(12,3)和Ⅰ(1,14)标记,测得其ESR波谱·氟化钠、重铬酸钾、丝裂霉素C和秋水仙素等环境诱变剂较显著地改变膜的序参数S和旋转相关时间,尤在膜表层,S和明显增大。温度曲线表明,人血的完整红细胞膜的相变点在膜表层和深层分别是38℃和40.0℃。在诱变剂作用下,膜类酯的动力学性质有明显变化。     

Human impacts on the terrestrial ecosystem of Fildes Peninsula of King George Island, Antarctica

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Cause and consequence of landscape fragmentation and changing disturbance by socio economic development in mountain landscape system of South Korea

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Comparing Forecasts of the Global Impacts of Climate Change

This paper utilizes the predictions ofseveral Atmosphere-Ocean GeneralCirculation Models and the Global ImpactModel to create forecasts of the globalmarket impacts from climate change. Theforecasts of market impacts in 2100 varyconsiderably depending on climate scenariosand climate impact sensitivity. The modelsdo concur that tropical nations will behurt, temperate nations will be barelyaffected, and high latitude nations willbenefit. Although the size of theseeffects varies a great deal across models,the beneficial and harmful effects areoffsetting, so that the net impact on theglobe is relatively small in almost alloutcomes. Looking only at market impacts,the forecasts suggest that while the globalnet benefits of abatement are small, thedistribution of damages suggests a largeequity problem that could be addressedthrough a compensation program. The largeuncertainty surrounding these forecastsfurther suggests that continued monitoringof both the climate and impacts isworthwhile.     

Influence of Llamas, Horses, and Hikers on Soil Erosion from Established Recreation Trails in Western Montana, USA

/ Various types of recreational traffic impact hiking trails uniquely and cause different levels of trail degradation; however, trail head restrictions are applied similarly across all types of packstock. The purpose of this study was to assess the relative physical impact of hikers, llamas, and horses on recreational trails. Horse, llama, and hiker traffic were applied to 56 separate plots on an existing trail at Lubrecht Experimental Forest in western Montana. The traffic was applied to plots at intensities of 250 and 1000 passes along with a no-traffic control under both prewetted and dry trail conditions. Soil erosion potential was assessed by sediment yield and runoff (using a Meeuwig type rainfall simulator), changes in soil bulk density, and changes in soil surface roughness. Soil moisture, slope, and rainfall intensity were recorded as independent variables in order to evaluate the extent that they were held constant by the experimental design. Horse traffic consistently made more sediment available for erosion from trails than llama, hiker, or no traffic when analyzed across wet and dry trail plots and high and low intensity traffic plots. Although total runoff was not significantly affected by trail user, wet trail traffic caused significantly greater runoff than dry trail traffic. Llama traffic caused a significant increase in sediment yield compared to the control, but caused erosion yields not significantly different than hiker traffic. Trail traffic did not increase soil compaction on wet trails. Traffic applied to dry trail plots generally resulted in a significant decrease in soil bulk density compared to the control. Decreased soil bulk density was negatively correlated with increased sediment yield and appeared to result in increased trail roughness for horse traffic compared to hiker or llama traffic. Differences described here between llama and horse traffic indicate that trail managers may want to consider managing packstock llamas independent of horses.KEY WORDS: Recreational impacts; Sediment yield; Trail degradation     

环境污染与人体健康

在正常环境中，环境中的物质与人体间保护动态平衡，污染物质破坏这一平衡，不仅会对人体健康造成急性危害，慢性危害和致癌，致畸，致突变等远期危害，而且这些危害具有影响范围大，作用时间长和情况复杂等特征。     

ECO-design of reuse and recycling networks by multi-objective optimization

An ECO-optimized reuse of process liquors addresses the financial gain and the effective use of resources. In processes that have a potential for process liquor recovery, the minimization of both economic and environmental burdens can be realised by an ECO-optimal design of reuse and recycling network (RRN).In this paper, a procedure for synthesizing such an RRN for a metal finishing process is investigated. The simultaneous analysis of environmental impact sensitivity (SAEIS) based on a superstructure approach, combined with multi-objective optimization is performed by mixed-integer nonlinear programming (MINLP). This allows an “eco–eco” trade-off i.e. total annualized cost and environmental impacts are minimized simultaneously. By varying the weighting factor, different RRN alternatives were generated. A replacement of the standard and closed-loop system by these solutions, even for the environmentally friendliest case, yielded a reasonable cost saving on raw material's inputs.     

城市人居环境生态评估方法探索——以南通市为例

以南通市为例,探索宏观层面的城市人居环境生态评估方法.通过统计、整理南通市人居环境数据资料,建立城市人居环境宏观评估模型及其评估指标体系(共25项指标),进而分析并评价南通市人居环境整体现状.