2000年北京大气中SO2浓度削减50%的健康效益—人力资本法实例研究

人力资本法是评估环境污染健康损害价值（或治理污染的健康效益）的常用方法，但在发达国家，它逐渐被隐含价格法等所取代。本文通过实例研究，探讨了人力资本法在我国目前的适用性，研究结果表明，当使用流行病学关于疾病负担的计量方法（ＹＰＬＬ）时，人力资本法在我国有很大的适用性。     

自然·水·人

人类社会向前发展,人向自然界的索取不断增加,对自然的干扰也逐步加剧,致使自然界的承受能力受到影响,人与自然的关系出现紧张。为此,人必须处理好与自然的关系,以免人的生存环境受到威胁。水是自然界的重要因素,和人的生存与人类社会的发展关系密切。由于用水量不断增加和用水不当,一些地区出现水资源危机,人在和水旱灾害进行抗争中,也出现了由于措施不当带来的人为加大灾害的问题。因此,人必须在处理好与自然关系的框架中,认真处理好与水的关系,以保障水资源的永续利用和人类社会的可持续发展。     

居室环境与人体健康

从居室污染的来源和主要污染物、居室污染对健康的危害等几个方面,阐述了居室环境与人体健康的关系.由于化学、物理及生物等多种污染物共同存在,对健康产生的危害往往比单一因素要复杂得多,控制居室环境污染,对于保护人体健康有至关重要的意义.提出了降低居室污染的措施和方法.     

Serum alpha-fetoprotein and neural tube defects in the first trimester of pregnancy

As part of the Medical Research Council randomized trial of vitamin supplementation in the prevention of neural tube defects (NTDs), maternal serum alpha-fetoprotein (AFP) was available for 19 NTD pregnancies. Each of these was matched with four unaffected controls, by maternal age, participating centre, and duration of sample storage. The samples came from women whose gestational age ranged from 6 to 14 completed weeks. The median AFP level in the affected pregnancies was 1·2 multiples of the median value in unaffected pregnancies of the same gestational age (95 per cent confidence interval (CI) 0·83–1·59). This confirmed the view that serum AFP measurement is of no practical value in the detection of NTDs in the first trimester of pregnancy. The study also showed that folic acid supplementation, used as a method of preventing NTDs, had no effect on the concentrations of maternal serum AFP up to 14 weeks of pregnancy.     

Amniotic fluid alpha-fetoprotein levels and prenatal diagnosis of autosomal trisomies

Pregnancies with fetal trisomy 21 have been associated with low amniotic fluid alpha-fetoprotein levels (AFAFP). This observation led to the suggestion that low AFAFP levels be used as a criterion for completion of a chromosomal analysis in patients who are not otherwise at increased risk for a fetal chromosome abnormality and in whom karyotyping might not have been completed for economic reasons. In order to assess the usefulness of such criteria, we reviewed the AFAFP levels of 90 cases of fetal trisomy 21, 23 cases of trisomy 18, and 10 cases of trisomy 13. These were compared with 2400 control samples with normal chromosome constitution. AFAFP levels were generally lower in pregnancies with trisomy 21, showing a median value of 0·72 MoM. However, 40 per cent of the trisomy 21 samples had AFAFP values greater than 0·8 MoM and 20 per cent were over 1·0 MoM. These data imply that over 50 per cent of Down syndrome cases might have been missed using a cut-off level of 0·70 MoM for completion of chromosome analysis. Using a higher cut-off level will leave only a small percentage of samples unkaryotyped. The distribution of AFP levels in trisomy 13 and 18 is no different from controls; we therefore believe that fetal karyotyping should be completed in every amniotic fluid sample obtained.     

环境污染对人群健康影响评价及其经济损失估算

为了定量地描述环境污染对人群健康的危害及其相应的经济损失，本文认为应对健康风险评价和人力资本法作进一步的研究，以便给出统一的规范化评价程序和计算方法。文中还对有关内容作了简要介绍。     

二噁英的毒性与防治

分析了二英的化学结构与毒性的关系，二英的来源，对人体健康的潜在危害以及可能造成的环境污染，提出了防治措施。     

Maternal Serum CA 125 for aneuploidy detection in early pregnancy

Maternal serum CA 125 levels were determined at 9–11 menstrual weeks for 26 cases of trisomy 13 (n = 4), trisomy 18 (n = 7), trisomy 21 (n = 15), and appropriate controls. There were no statistically significant differences between groups.     

Assay of some volatile compounds in human exhalation

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