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101.
Robert C. Lee James R. Fricke William E. Wright Walt Haerer 《Environmental geochemistry and health》1995,17(4):169-181
A partially probabilistic blood lead prediction model has been developed, based on the US Environmental Protection Agency integrated exposure-uptake-biokinetic blood lead model (IEUBK model). This study translated the IEUBK model into a spreadsheet format. The uptake submodel incorporates uncertainty distributions for exposure and bioavailability parameters. The biokinetic submodel is duplicated with a table incorporating partitioning and decay of lead levels in the body. As a case study, the probabilistic model is applied to a lead exposure scenario involving a former smelter site in Sandy, Utah. The probabilistic model produces less biased estimates of means and standard deviations than the deterministic model. Parameter uncertainty is propagated in the model by the use of Monte Carlo simulation. Thus, sensitivity analysis is possible, and driving variables can be determined. 相似文献
102.
Twenty Henna samples were collected and analysed for lead by electrothermal atomic absorption spectrophotometry after a microwave acid digestion procedure. The mean lead concentration was 5.50 g g–1, with a range from 1.29 g g–1 to 16.48 g g–1. The data did not show a high concentration of lead in these samples. However, if we take into account the popular use of henna, the cumulative effects of prolonged exposure to low lead especially in children cannot be ruled out. 相似文献
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105.
A controlled hydroponic experiment was undertaken to investigate Cd uptake in relation to the activity of Cd species in solution other than the free ion (Cd2+) by maintaining a constant Cd2+ activity under variable SO42− and Cl− concentrations exposed to maize (Zea mays var. Cameron) plants. The objectives of these experiments were: (1) to distinguish and quantify the different uptake rates of free and inorganic-complexed Cd from nutrient solution, and (2) to model the uptake of Cd by maize with a Biotic Ligand Model (BLM) in a system which facilitates the close examination of root characteristics. Results of the current experiments suggest that, in addition to the free ion, CdSO40 complexes are important factors in determining Cd uptake in nutrient solution by maize plants. Higher nominal SO42− concentrations in solution generally resulted in a greater Cd accumulation by maize plants than predicted by the Cd2+ activity. A better integration of the complete dataset for the 3 harvest times (6, 9 and 11 days after treatment) was achieved by including consideration of both the duration of Cd exposure and especially the root surface area to express Cd uptake. Similarly, the fit of the BLM was also improved when taking into account exposure time and expressing uptake in terms of root morphological parameters. 相似文献
106.
Sound stimulates the tympanic membrane (TM) of anuran amphibians through multiple, poorly understood pathways. It is conceivable
that interactions between the internal and external inputs to the TM contribute to the nonlinear effects that noise is known
to produce at higher levels of the auditory pathway. To explore this issue, we conducted measurements of TM vibration in response
to tones in the presence of noise in the frog Eupsophus calcaratus. Laser vibrometry revealed that the power spectra (n = 16) of the TM velocity in response to pure tones at a constant level of 80 dB sound-pressure level (SPL) had a maximum
centered at an average frequency of 2,344 Hz (range 1,700–2,990 Hz) and a maximum velocity of 61.1 dB re 1 μm/s (range 42.9–66.6
dB re 1 μm/s). These TM-vibration velocity response profiles in the presence of increasing levels of 4-kHz band-pass noise
were unaltered up to noise levels of 90 dB SPL. For the relatively low spectral densities of the noise used, the TM remains
in its linear range. Such vibration patterns facilitate the detection of tonal signals in noise at the tympanic membrane and
may underlie the remarkable vocal responsiveness maintained by males of E. calcaratus under noise interference. 相似文献
107.
Community-based vulnerability assessment has often assumed that the local is the relevant level of adaptation to climate change.
This paper suggests that not only do a number of levels from the international to the regional influence which adaptations
can take place locally, but the governance network that is made up by actors on different levels may to a large extent be
formed in responses to globalising factors, such as internationalisation of economies and the changing role of the state.
The paper presents a study of adaptation in reindeer (Rangifier tarandus) herding, forestry and fishing communities in northern Norway, Sweden, and Finland, with a focus on assessing stakeholders’
own perceptions of environmental, socio-political and economic factors that affect them. In general, the paper illustrates
the integration of non-subsistence economies into large and complex interactions where local adaptation is a result of the
sum of stresses impacting individual entrepreneurs, and the potential they have to adapt their practices given governance
(and their access to support) on different scales.
相似文献
E. Carina H. KeskitaloEmail: |
108.
Occupational exposure limits (OELs) developed by authorities play a key role in the implementation of programs to protect workers against hazardous chemicals. Unfortunately, many hazardous substances do not have OELs or the OEL could be outdated. To assure the health of the workers, it is therefore useful for companies to develop corporate OELs. An inhouse strategy will be presented hereafter. Expertise in toxicology, industrial hygiene, and occupational health should be available within the company and clear selection criteria for substances are needed. A corporate OEL is only developed for hazardous substances (e.g., carcinogenic or reprotoxic) with a high potential for worker exposure when an appropriate national OEL or threshold limit value is not available. The methodology to calculate corporate OELs is based on the existing methods for national or community OELs and also on the guidance from the European Union's (EU) regulation on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH). For carcinogenic substances with a nonthreshold mode of action, there is always a residual chance that a cancer develops even when the exposure of workers is low. To establish an OEL for these substances, the “German traffic light model” is recommended. It is pragmatic, defines an unacceptable, tolerable, and acceptable risk level when workers are exposed to these substances, and determines risk management for exposure reduction. Overall, the professional practice to develop OELs is a good example of corporate leadership to proactively protect the health of workers. 相似文献
109.
介绍了二甲基甲酰胺(DMF)在人体的代谢、毒性作用和临床表现,以及DMF职业接触标志物的研究进展。 相似文献
110.