Screening for fetal aneuploidies at 11 to 13 weeks

Effective screening for major aneuploidies can be provided in the first trimester of pregnancy. Screening by a combination of fetal nuchal translucency and maternal serum free-β-human chorionic gonadotrophin and pregnancy-associated plasma protein-A can identify about 90% of fetuses with trisomy 21 and other major aneuploidies for a false-positive rate of 5%. Improvement in the performance of first-trimester screening can be achieved by firstly, inclusion in the ultrasound examination assessment of the nasal bone and flow in the ductus venosus, hepatic artery and across the tricuspid valve, and secondly, carrying out the biochemical test at 9 to 10 weeks and the ultrasound scan at 12 weeks. Copyright © 2011 John Wiley & Sons, Ltd.     

游离态金属络合物解离稳态动力学的数学模拟

在有配位体存在的条件下，利用阳极溶出伏安法测得的水相游离金属含量通常偏高，本研制根据电化学、化学动力学和迁移动力学的基本原理，建立了描述扩散层中金属络合物解离反应和不同形态物质迁移过程中的物理模型和相应的数学模型。     

多元可燃性混合气体爆炸中间产物发射光谱特性实验研究

从矿井火区实际出发,选用类似于煤矿开采现场产生的多元可燃性气体:CH4,C2H6 ,C2H4,CO,H2 ,利用瞬态光谱测量系统探究了爆炸引发阶段中间产物的光谱特征,分析了组分配比、组分浓度和甲烷浓度对压力特性和中间产物光谱的影响。研究结果表明:在多组分气体加入量较小（未形成体系贫氧状态）时,3种自由基发射光谱峰值出现时间随着甲烷浓度的增大先缩短后延长;在多组分气体加入量较大（形成体系贫氧状态）时,自由基发射光谱峰值出现时间随着甲烷浓度的增大不断延长;当其以任意比例混合后,微观反应过程中关键自由基的出现顺序为:OH自由基先于O自由基, O自由基先于H自由基出现。     

INTERFERENCE BETWEEN GRAVITY WELLS STEADY STATE FLOW1

Under steady state conditions of flow, the seepage toward a single gravity well is governed by the Laplace Equation which may be written in terms of either the hydraulic head, the pressure head or the velocity potential. Although this equation is linear, the principle of superposition cannot be applied to sum up the individual effects in the case of a multiple gravity well system due to the variation of the flow domain under the effect of one or several wells. A method is presented allowing the use of the superposition principle in a restricted form. The superposition of the decrements of the base pressure heads than the initial heads before pumping is valid. Also the decrements in the areas of the pressure head diagrams across specific vertical sections than the original areas can be summed up together.     

坐姿时上肢作业姿势舒适性评价

针对人体呈现坐姿状态时前侧方作业区域的不同,利用人体测量数据在空间划分网格,实现了上肢作业姿势的参数化定义。并设计实验,由12位健康的男被试参加,利用自由模量幅度估计法对定义过的384种作业姿势的舒适性进行了评价和分级。对依据不同被试个数计算出的结果进行比较分析,并与快速上肢评价方法的评价结果进行比对,揭示了结果的可靠性。评价结果可以为操纵装置的工效设计以及作业空间布局提供重要参考,同时为国内的姿势舒适性评价工作提供了可靠的依据。     

Radical Scavengers Suppress Low Frequency EMF Enhanced Proliferation in Cultured Cells and Stress Effects in Higher Plants

Summary In previous publications, we reported that sinusoidal varying magnetic fields (SVMF) modify the activity and dynamics of the malignancy marker adenosine deaminase, and enhance the proliferation of chick embryo fibroblasts (CEF). While the SVMF examined by us (50, 60 & 100 Hz / 0.06–0.7 mT) were all below kT, they may have the potential of altering chemical processes in which excited radicals are involved. We tested this hypothesis in two experimental systems: CEF in culture and Spirodela oligorrhiza (Lemnaceae) (a small aquatic plant, commonly known as Duckweed). CEF were exposed to SVMF of 100 Hz/0.7 mT for 24 h. The addition of the exogenous radical scavengers catalase, superoxide dismutase or vitamin E to the cells during exposure significantly suppressed enhancement of cell proliferation caused by the field (by 79, 67 and 82%, respectively, as evaluated by the MTT colorimetric assay). ¹⁵N NMR analysis of Duckweed plants fed by ¹⁵N-labeled ammonium chloride and exposed to SVMF at 60 and 100 Hz/0.7 mT for 24 h, revealed augmented alanine production. Alanine did not accumulate in the absence of SVMF. The addition of vitamin C, a radical scavenger, reduced alanine production by 82%. Exposure to SVMF resulted in specific metabolic stress effects in Duckweed plants and enhanced proliferation of CEF. In both cases, it is suggested that free radicals are involved.