水生生物急性毒性QSAR模型研究进展

化学品污染对人类健康和生态环境造成潜在风险。但是,危害性信息缺失是进行化学品风险评价的主要挑战。经济合作与发展组织(OECD)和美国环保署都提倡用非动物实验替代方法来弥补数据缺失。定量结构-活性关系(QSAR)被认为是一种有应用前景的替代技术。水生生物急性毒性是化学品风险评估和优先污染物筛选中最常用的参数之一。但是,目前可获得的实验毒性数据非常有限。本文总结了近年来发展的急性毒性预测模型,包括:(1)基于同类化合物建模;(2)基于数理统计建模;(3)基于化合物毒性作用模式建模。从模型预测能力、应用域、机理解释等角度对这3类模型进行了比较。其中,基于作用模式构建的模型一般具有较好的预测性能,并有助于机理解释,将是今后水生生物急性毒性预测的发展方向。     

Inadvertent environmentalism and the action–value opportunity: reflections from studies at both ends of the generational spectrum

A recent turn towards a more contextually sensitive apprehension of the challenge of making everyday life less resource hungry has been partly underwritten by widespread evidence that the environmental values people commonly profess to hold do not often translate into correspondingly low impact actions. Yet sometimes the contexts of everyday life can also conspire to make people limit their consumption without ever explicitly connecting this to the environmental agenda. This paper considers this phenomenon with reference to UK studies from both ends of the generational spectrum. The first questioned how older people keep warm at home during winter and the second examined how young people get rid of no longer wanted possessions. Both found that, though the respondents involved were acting in certain ways that may be deemed comparatively low impact, they were hitherto relatively indifferent to the idea of characterising these actions as such. We outline three ways in which sustainability advocates might respond to the existence of such “inadvertent environmentalists” and consider how they might inspire studies that generate fresh intervention ideas instead of lingering on the dispiriting recognition that people do not often feel able to act for the environment.     

干水在热环境中的持续作用效果研究*

为研究干水对建筑火灾中高聚物燃烧产生的热危害和烟气危害的影响,采用火焰传播量热仪（FPA）模拟建筑火灾扑灭后的持续热环境,对灭火过程中过量施加的干水对可燃高聚物的持续作用效果进行研究。结果表明:干水能够明显提升可燃物的抗复燃性能以及削弱燃烧过程中的热危害和烟气危害;相比于纯燃料,干水作用下可燃物的点燃时间出现明显的延迟,并且热释放速率和一氧化碳生成速率明显降低,尤其在可燃物燃烧初期,干水还具有显著的抑制烟气生成速率的效果。研究结果可为灾后消防人员的搜救和被困人员的逃生提供一种新的技术方案。     

Forecast-based action for conservation

Extreme weather events pose an immediate threat to biodiversity, but existing conservation strategies have limitations. Advances in meteorological forecasting and innovation in the humanitarian sector provide a possible solution—forecast-based action (FbA). The growth of ecological forecasting demonstrates the huge potential to anticipate conservation outcomes, but a lack of operational examples suggests a new approach is needed to translate forecasts into action. FbA provides such a framework, formalizing the use of meteorological forecasts to anticipate and mitigate the impacts of extreme weather. Based on experience from the humanitarian sector, I suggest how FbA could work in conservation, demonstrating key concepts using the theoretical example of heatwave impacts on sea turtle embryo mortality, and address likely challenges in realizing FbA for conservation, including establishing a financing mechanism, allocating funds to actions, and decision-making under uncertainty. FbA will demand changes in conservation research, practice, and governance. Researchers must increase efforts to understand the impacts of extreme weather at more immediate and actionable timescales and should coproduce forecasts of such impacts with practitioners. International conservation funders should establish systems to fund anticipatory actions based on uncertain forecasts.     

配筋率对钢筋混凝土框架梁极限承载力的影响——拱效应试验研究

通过对9根不同纵筋配筋率的钢筋混凝土试验梁进行加载试验,研究了纵筋配筋率对钢筋混凝土框架梁拱效应的影响以及拱效应条件下钢筋混凝土框架梁的极限承载力.试验结果和理论分析表明,钢筋混凝土框架梁中的拱效应可以使构件的极限承载力提高1倍左右;纵筋配筋率越低,极限承载力提高的幅度越显著.为提高拱效应的作用,宜将钢筋混凝土框架梁的纵筋配筋率控制在1.5%以内.     

莱茵河流域防洪规划——发展及其实施(论文摘编)

The River Rhine situatedin the middle of central Europe is a striking example for the diverging con-cerns of natural wetland schemes and human uses.The River Rhine basin covers an area of190000km2andis settled by50million people,livingin nine different countries.Onlyin the19th century the naturalmoving water courses of the River Rhine were fixedin a singular riverbed allowingthe human utilization ofthe flood prone areas by agriculture,settlement andinfrastructure.Extreme floods in the last …     

Swarm cognition in honey bees

We synthesize findings from neuroscience, psychology, and behavioral biology to show that some key features of cognition in the neuron-based brains of vertebrates are also present in the insect-based swarm of honey bees. We present our ideas in the context of the cognitive task of nest-site selection by honey bee swarms. After reviewing the mechanisms of distributed evidence gathering and processing that are the basis of decision making in bee swarms, we point out numerous similarities in the functional organization of vertebrate brains and honey bee swarms. These include the existence of interconnected subunits, parallel processing of information, a spatially distributed memory, layered processing of information, lateral inhibition, and mechanisms of focusing attention on critical stimuli. We also review the performance of simulated swarms in standard psychological tests of decision making: tests of discrimination ability and assessments of distractor effects.     

我国持久性有机污染物状况及宏观对策

从近几十年来中国POPs的使用情况出发 ,系统分析了典型POPs物质在农产品、土壤、母乳、水体和沉积物等介质中的污染状况。分析了国际上控制POPs的动向以及中国采取的应对策略 ,并对中国控制POPs污染的宏观对策进行探讨。从总体上看 ,目前中国有关POPs的政策法规体系正逐渐与国际接轨 ,但还很不完善 ,缺乏针对性和对污染事故的责任、处罚等明确措施 ,控制POPs对环境的污染与危害 ,制定行之有效的环境监管措施势在必行。     

自贸区效应下山东省渔业资源开发基准选择

国家间自贸区的设立,将更加有利于各签约国资源环境利用效率的提升。本文采用贸易指数测算方法,分析了中、挪、韩在海水产品生产、加工及贸易流通中的各自优势。挪威因丰富的渔业资源和先进的渔业技术,在海水产品养殖及加工领域中具有全球引领作用;韩国有相对更加严格的海水产品安全检疫检验体系,可以确保海水产品的品质安全。随着中韩自贸区的实施及中挪重启双边自贸协定谈判,三国海洋渔业彼此间将进入自贸型竞争态势。如何运用自贸区效应,积极促进渔业资源开发比较潜能的发挥,进一步融入全球化,对于我国,尤其是对山东省渔业实现跨越式发展都是一个亟待破解的课题。山东省作为中国第一渔业大省,在继"海上山东"战略实施基础上,又率先提出"海上粮仓"建设规划设想。针对目前山东省渔业发展中存在的瓶颈问题,本文结合全球贸易分析模型(GTAP)的模拟,在中挪、中韩自贸区背景下对各方海水产品贸易的影响进行了系统分析,提出:在当前海水养殖产量大于捕捞产量的格局下,山东"海上粮仓"建设应以自贸区制度所形成的倒逼机制为互动机理,切实落实海产品养殖生产的安全标准底线和生态系统水平提升的两个基准维度,全面践行可持续健康的渔业资源开发理念,在全国先行完成开放型"海上粮仓"示范体系的建设,以推动我国海水产品生产与加工从量到质的转型,实现海水资源开发与生态环境保护并举,提升我国海洋渔业的国际竞争力。     

有机污染物对发光菌和鱼的毒性相关性研究

研究有机污染物对不同水生生物毒性的种间关系有助于探讨有机污染物对水生生物的毒性作用模式。本文应用1 470种有机化合物对发光菌的毒性数据和949种有机化合物对鱼的毒性数据,研究有机化合物对发光菌和鱼的种间毒性作用模式。结果表明,有机化合物对发光菌和鱼的毒性呈正相关,但种间相关性较差。通过计算毒性比率TR值表明多数类别有机化合物具有相似的种间毒性作用模式。基线和弱惰性化合物对发光菌和鱼的毒性均与辛醇水分配系数log Kow具有良好的线性关系,这说明基线和弱惰性化合物在发光菌和鱼体内的残余量CBR值均为一个常数。这些化合物对发光菌和鱼具有相似的毒性作用模式和生物吸收过程。另外,一些亲水性化合物的log TR值具有较大的种间差异,即对发光菌和鱼的毒性效应具有较大的种间差异,表明亲水性化合物对发光菌为反应型化合物,而对鱼为麻醉型化合物。有机化合物对发光菌和鱼的毒性种间相关性通过引入疏水性参数得到了一定的改善,这表明这些亲水性化合物毒性效应的种间差异有一部分归因于有机化合物在发光菌和鱼体内的生物富集不同,而不是由于与生物分子的反应性不同。这些亲水性化合物相对于鱼的腮和皮肤更容易通过发光菌的细胞膜,与生物分子发生化学反应,从而具有较高的毒性效应。Log Kow大于7的化合物对发光菌和鱼均具有较低的毒性,说明有机化合物在生物体内的富集能力对有机化合物剩余毒性的判别起着重要作用。