在大鼠哮喘发生中SO2致凋亡相关基因及蛋白质表达的改变

为了研究SO2对哮喘大鼠肺细胞凋亡相关基因mRNA和蛋白表达的影响.对健康雄性Wistar大鼠随机分为正常组、SO2暴露组、卵蛋白(OVA)致敏哮喘组、SO2和OVA联合作用组,采用荧光实时定量RT-PCR和Westem Blot方法研究吸入SO2对哮喘大鼠肺细胞p53、box、bcl-2三种细胞凋亡相关基因mRNA和蛋白表达的影响.结果表明,SO2暴露组肺中p53和box mRNA和蛋白水平降低,bcl-2表达和bcl-2/bax比值均有升高,但与对照组相比无显著性差异.与对照组相比,哮喘组肺中p53和bax mRNA和蛋白的表达水平呈现不同程度的降低;bcl-2的表达和bcl-2/bax比值显著升高.SO2和OVA联合作用后,与哮喘组相比,肺中p53和bax蛋白表达显著下降,而bcl-2蛋白表达显著升高.结论:SO2可加剧哮喘大鼠的哮喘症状,其机制可能是通过影响哮喘大鼠肺组织凋亡相关基因(p53、bax、bcl-2)的表达水平,抑制气道炎性细胞的凋亡来实现的.这些机制的阐明有助于对SO2毒作用机制的理解和所致疾病的治疗.     

Farm soil carbon monitoring developments and land use change: unearthing relationships between paddock carbon stocks, monitoring technology and new market options in Western Australia

This research provides a synthesis of soil organic carbon (SOC) densities in a range of Australian soils and land use types to decrease uncertainties in agricultural soil carbon (C) sequestration investments. This work provides information on existing Australian C soil stocks, the relationships between SOC with various agricultural and forestry land use changes, and options available for agriculturalists to cultivate and safeguard their C stocks. This work also includes recent developments in C rights, soil C monitoring, and verification technologies and procedures now in use for C stock inventories. This review has a special focus on known changes in SOC stocks, technological and methodological developments in the agricultural region of southern Western Australia (WA).     

Modelling the Karenia mikimotoi bloom that occurred in the western English Channel during summer 2003

Observations from space and in situ from the R.V. Corystes 8/03 Cruise show that a massive Karenia mikimotoi bloom occured during summer 2003 in the western English Channel. Due to exceptional climatoligical conditions that occured in June 2003, the installation of a very strong thermocline enhanced the development of a massive bloom over 1 million cells l⁻¹ in the Central English Channel. This paper presents the application of a mathematical model of this species, previously developed in for the Bay of Biscay, into a general 3D model of the primary production of the English Channel and southern Bight of the North Sea. Allelopathic interactions exerted by K. mikimotoi on other phytoplankton species and the role of agitation in the mortality of this species are taken into account. The model includes the dynamics of the bloom and consequently reproduces with good agreement the geographical distribution of the K. mikimotoi bloom both surface and subsurface. The model suggests that the apparent transport of the bloom towards the French coasts as inferred from the satellite observation was not due to advection but was only caused by the establishment of suitable conditions. The sensivity of the K. mikimotoi distribution to boundary conditions, initialization and the role of turbulence is discussed.     

环境影响评价与西部大开发的可持续发展

环境影响评价作为协调经济发展与环境保护关系的重要手段,将在西部大开发中发挥重要作用。本文从可持续发展的高度,提出进一步完善环境影响评价的具体对策,以确保实现西部大开发的可持续发展。     

Vertical distributions of (99)Tc and the (99)Tc/(137)Cs activity ratio in the coastal water off Aomori, Japan

Using a sector-field ICP-MS the vertical distributions of the ⁹⁹Tc concentration and ⁹⁹Tc/¹³⁷Cs activity ratio were measured in the coastal waters off Aomori Prefecture, Japan, where a spent-nuclear-fuel reprocessing plant has begun test operation. The ⁹⁹Tc concentrations in surface water ranged from 1.8 to 2.4 mBq/m³, no greater than the estimated background level. Relatively high ⁹⁹Tc/¹³⁷Cs activity ratios (10-12 × 10⁻⁴) would be caused by the inflow of the high-⁹⁹Tc/¹³⁷Cs water mass from the Japan Sea. There is no observable contamination from the reprocessing plant in the investigated area. The ⁹⁹Tc concentration and the ⁹⁹Tc/¹³⁷Cs activity ratio in water column showed gradual decreases with depth. Our results implied that ⁹⁹Tc behaves in a more conservative manner than ¹³⁷Cs in marine environments.     

海南西部资源环境一体化研究

传统发展模式引发的资源环境问题迫使人类思考去寻求新的可持续的发展模式,资源环境一体化就是适应此背景的新兴发展理念。以海南西部沙地环境资源化与山区资源环境化的发展实践,实证分析了资源环境一体化的发展模式与发展机制。按资源与环境是可相互转化的这一资源环境一体化理论基础,海南西部干旱与多沙的环境可将其作为旅游资源进行开发,而针对山区资源过度利用的现状,则通过实施设立自然保护区、退耕还林、封山育林等措施实行保护性开发,实现山区资源环境化。重视环境与可持续发展思想、资源与环境的同源性与资源时效性、科学发展与技术进步、环境政策的完善与严格、政府与企业推进是促进资源环境一体化的主要推动机制。     

南水北调西线一期工程调水河流之间实施补偿调度的可能性分析

以道孚、绰斯甲、足木足水文站1960～2000年的同步天然年径流量系列为基础,应用Copula方法构造了南水北调西线一期工程调水河流之间的径流联合分布模型,具体分析了鲜水河、绰斯甲河、足木足河这3条调水河流之间实施补偿调度的概率。结果表明：鲜水河与足木足河之间实施补偿调度的可能性最大,绰斯甲河与足木足河之间实施补偿调度的可能性次之,鲜水河与绰斯甲河之间实施补偿调度的可能性最小,其概率分别为4374％、3884％和2582％。
     

Calibrating and monitoring the western gray whale mitigation zone and estimating acoustic transmission during a 3D seismic survey, Sakhalin Island, Russia

A 3D marine seismic survey of the Odoptu license area off northeastern Sakhalin Island, Russia, was conducted by DalMorNefteGeofizika (DMNG) on behalf of Exxon Neftegas Limited and the Sakhalin-1 consortium during mid-August through early September 2001. The key environmental issue identified in an environmental impact assessment was protection of the critically endangered western gray whale (Eschrichtius robustus), which spends the summer–fall open water period feeding off northeast Sakhalin Island in close proximity to the seismic survey area. Seismic mitigation and monitoring guidelines and recommendations were developed and implemented to reduce impacts on the feeding activity of western gray whales. Results of the acoustic monitoring program indicated that the noise monitoring and mitigation program was successful in reducing exposure of feeding western gray whales to seismic noise.     

西部大开发：城镇化建设与农田资源保护协调发展问题

城镇作为现代经济生活的主载体,对经济发展的作用巨大,然而城镇的建设与发展又是要占用大量农田资源。我国地少人多,土地资源稀缺,现行可耕地主要集中于中、西部地区,因此西部大开发,妥善处理城镇化建设与农田资源保护协调发展关系就显得尤为重要。本文在论述城镇化建设与农田资源保护的矛盾现状基础之上,试图提出西部地区城镇化建设中相应的农田资源保护对策。     

西部大开发要走可持续发展之路

西部地区生态环境条件十分脆弱,水土流失、荒漠化问题严重;各种自然灾害多发,远离目前国家的经济发展中心,由于距离远远输成本高使自然资源失去了价格上的部分优势。西部地区自然条件和经济社会发展的特殊性,要求我们在西部大开发中坚持生态建设,保护环境,节约资源,趋利避害,推进城市化,依靠科技创新,以最小的资源环境代价发展经济,实现人口资源、环境与经济社会发展的良性循环。