Apert syndrome: what prenatal radiographic findings should prompt its consideration?

Apert syndrome was diagnosed in a newborn with typical facial and digital features whose only detected prenatal abnormality had been agenesis of the corpus callosum. This prompted a review of the central nervous system findings in all cases of Apert syndrome treated at the Craniofacial Center Boston Children's Hospital between 1978 and 2004. Two of 30 patients with Apert syndrome had prenatal identification of mild dilatation of the lateral cerebral ventricles and complete agenesis of the corpus callosum (ACC) documented with both ultrasound and MRI. Both had the common S252W mutation of FGFR2. Though cranial and orbital malformations typical of Apert were eventually seen in these fetuses in the third-trimester, even in retrospect, these were not detectable at mid second-trimester, ultrasound screening for congenital malformations. Hand malformations also went undetected in the second-trimester despite extensive imaging by experienced radiologists. We conclude that prenatal ultrasonographic identification of mild ventriculomegaly or ACC should stimulate a careful search for features of Apert syndrome and prompt follow-up imaging to look for bony abnormalities that have later onset. Prenatal molecular testing for Apert mutations should be considered in cases of mild ventriculomegaly and ACC. Copyright © 2006 John Wiley & Sons, Ltd.     

How the diversity of human concepts of nature affects conservation of biodiversity

Protecting nature has become a global concern. However, the very idea of nature is problematic. We examined the etymological and semantic diversity of the word used to translate nature in a conservation context in 76 of the primary languages of the world to identify the different relationships between humankind and nature. Surprisingly, the number of morphemes (distinct etymological roots) used by 7 billion people was low. Different linguistic superfamilies shared the same etymon across large cultural areas that correlate with the distribution of major religions. However, we found large differences in etymological meanings among these words, echoing the semantic differences and historical ambiguity of the contemporary European concept of nature. The principal current Western meaning of nature in environmental public policy, conservation science, and environmental ethics–that which is not a human artifact–appears to be relatively rare and recent and to contradict the vision of nature in most other cultures, including those of pre-Christian Europe. To avoid implicit cultural bias and hegemony–and thus to be globally intelligible and effective–it behooves nature conservationists to take into account this semantic diversity when proposing conservation policies and implementing conservation practices.     

环境公益诉讼立法问题研究

随着社会生产力的飞速发展,环境问题日益突出。环境公益诉讼是解决环境问题,保护国家、社会和公众环境权益的基本形式和有效途径,也是最后屏障。从国内一起环境公益诉讼案件出发,借鉴国外特别是美国环境公益诉讼的经验,提出了建立我国环境公益诉讼制度的若干立法建议,旨在探索一条落实科学发展观的环境保护新思路。     

What Is the Environment Doing in My Report? Analyzing the Environment-as-Stakeholder Thesis through Corpus Linguistics

This paper seeks to explore whether business organizations' claims to regard the natural environment as a stakeholder are consistent with the way in which the environment is represented in their corporate social responsibility reporting. It applies corpus linguistic methods to analyze statistical regularities and differences in the discursive construction of core stakeholders, such as customers and employees, and that of the natural environment. Results show that the representation of the environment is not characterized by the agency and capacity for engagement that characterizes other stakeholders. While organizations overtly acknowledge a duty toward the environment, the dominant lexical and grammatical patterns in which it is represented tend to obscure the organization's responsibilities and emphasize its mitigating actions instead. Although the argument for regarding the environment as a stakeholder is based on the fact that it places objective and compelling demands on our actions, we look in vain for recognition of such demands in organizational reporting.