对随机振动试验方法的探讨

本文详细介绍了随机振动试验过程中存在的振台推力估算方法、夹具设计安装、控制/响应传感器的安装方法,对试验前的准备及试验过程的实施进行了描述,探讨了试验过程中发生的中断及其处理方法。     

冲击响应谱规范试验室模拟述评

冲击响应谱试验已是航天产品必做的力学环境试验,本文介绍了目前试验室普遍使用的冲击响应谱模拟的手段,阐述了用电动振动台模拟和用机械式试验机模拟的差异,并对存在的差异进行了讨论。     

基于系统动力学—投入产出分析整合方法的江苏省产业用水综合效用分析

产业用水结构的欠合理一定程度上制约着社会的发展,如何科学评价产业用水情况,取得在经济效益、水资源和环境资源约束下的协调发展已成为目前区域社会经济发展面临与亟待解答的科学问题。以江苏省为例,提出了系统动力学—投入产出分析整合方法,在构建反映产业结构、用水结构和排污结构的互动反馈的水资源综合利用系统动力学模型基础上,通过敏感性分析确定对系统影响较大的关键变量,运用投入产出分析技术,对江苏省各部门用水特性、排污特性和经济效益特性进行计算测度,由此构建了3种产业发展模拟方案。依据系统动力学模型输出结果,对2025年3种方案下的重点产业部门用水综合效用情况进行对比分析,进而优选出"节水治污型"方案,并最后提出保障方案实施的对策建议,为江苏省产业和用水结构调整提供决策依据。     

国家级新区发展异质性及驱动机制研究——以上海浦东新区和南京江北新区为例

国家级新区建设是转型期国家推动新型工业化和城镇化战略的重要手段,推动了城市空间重构和功能重组,从而成为城市研究热点。从经济发展、人口集聚规模以及建设用地扩张三个维度刻画对比了上海浦东新区和南京江北新区的发展的异质性,并进一步剖析发展的驱动机制,发现两地发展异质性的表象原因是发展阶段的差异,更深层的是区域发展驱动机制的差异:交通等基础设施建设能强化新区与母城的联系,是实现新区快速健康发展的基础,浦东新区完善的交通运输体系对所在区域及全市的经济快速增长产生了重要影响;而全球资本汇聚、产城融合、城市大事件营销是新区快速发展的重要驱动力;发展型政府的作用及政治精英的影响力对国家级新区发展也具有重要的推动作用。基于上述研究,对于新型工业化和城镇化背景下新区的健康发展提出了政策建议。     

Silica nanoparticles and silver-doped silica nanoparticles induce endoplasmatic reticulum stress response and alter cytochrome P4501A activity

Engineered silica nanoparticles (SiO₂-NPs) find widespread application and may lead to exposure of humans and the environment. Here we compare the effects of SiO₂-NPs and SiO₂-NPs doped with silver (SiO₂-Ag-NPs) on survival and cellular function of human liver cells (Huh7) and Pimephales promelas (fathead minnow) fibroblast cells (FMH). In Huh7 cells we investigate effects on the endoplasmatic reticulum (ER), including ER stress, and interactions of nanoparticles (NPs) with metabolizing enzymes and efflux transporters. The NPs formed agglomerates/aggregates in cell culture media as revealed by SEM and TEM. SiO₂ and SiO₂-1% Ag-NPs were taken up into cells as demonstrated by agglomerates occurring in vesicular-like structures or freely dispersed in the cytosol. Cytotoxicity was more pronounced in Huh7 than in FMH cells, and increased with silver content in silver-doped NPs. Dissolved silver was the most significant factor for cytotoxicity. At toxic and non-cytotoxic concentrations SiO₂-NPs and SiO₂-1% Ag-NPs induced perturbations in the function of ER. In Huh7 cells NPs induced the unfolded protein response (UPR), or ER stress response, as demonstrated in induced expression of BiP and splicing of XBP1 mRNA, two selective markers of ER stress. Additionally, SiO₂-1% Ag-NPs and AgNO₃ induced reactive oxygen species. Pre-treatment of Huh7 cells with SiO₂-1% Ag-NPs followed by exposure to the inducer benzo(a)pyrene caused a significant reduced induction of CYP1A activity. NPs did not alter the activity of ABC transporters. These data demonstrate for the first time that SiO₂-NPs and SiO₂-1% Ag-NPs result in perturbations of the ER leading to the ER stress response. This represents a novel and significant cellular signalling pathway contributing to the cytotoxicity of NPs.     

Lead toxicity, defense strategies and associated indicative biomarkers in Talinum triangulare grown hydroponically

Talinum species have been used to investigate a variety of environmental problems for e.g. determination of metal pollution index and total petroleum hydrocarbons in roadside soils, stabilization and reclamation of heavy metals (HMs) in dump sites, removal of HMs from storm water-runoff and green roof leachates. Species of Talinum are popular leaf vegetables having nutrient antinutrient properties. In this study, Talinum triangulare (Jacq.) Willd (Ceylon spinach) grown hydroponically were exposed to different concentrations of lead (Pb) (0, 0.25, 0.5, 0.75, 1.0 and 1.25 mM) to investigate the biomarkers of toxicity and tolerance mechanisms. Relative water content, cell death, photosynthetic pigments, sulphoquinovosyldiacylglycerol (SQDG), anthocyanins, α-tocopherol, malondialdehyde (MDA), reactive oxygen species (ROS) glutathione (GSH and GSSG) and elemental analysis have been investigated. The results showed that Pb in roots and shoots gradually increased as the function of Pb exposure; however Pb concentration in leaves was below detectable level. Chlorophylls and SQDG contents increased at 0.25 mM of Pb treatment in comparison to control at all treated durations, thereafter decreased. Levels of carotenoid, anthocyanins, α-tocopherol, and lipid peroxidation increased in Pb treated plants compared to control. Water content, cells death and elemental analysis suggested the damage of transport system interfering with nutrient transport causing cell death. The present study also explained that Pb imposed indirect oxidative stress in leaves is characterized by decreases in GSH/GSSG ratio with increased doses of Pb treatment. Lead-induced oxidative stress was alleviated by carotenoids, anthocyanins, α-tocopherol and glutathione suggesting that these defense responses as potential biomarkers for detecting Pb toxicity.     

新吹填软土地基复式负压固结技术开发

新吹填土含泥量大、含水率大、渗透性差、零承载力,常规地基处理工法无法开展,地基处理面临诸多困难。针对该问题,提出了复式负压固结技术,该技术包括3道工序:改性真空预压、电渗降水和强夯动力固结。改性真空预压使地基得到初步固结,具备一定强度,为后序工作做准备;电渗降水可有效降低夯前地下水位和土体含水率,并促进夯后超孔隙水压力的消散;电渗降水和强夯动力固结多遍耦合,共同对吹填土进行地基加固。现场开展了复式负压固结技术工艺试验、土性试验和沉降变形监测。结果表明,应用于吹填泥的地基处理,改性真空预压可快速提高承载力,电渗法可迅速降低地下水位,有效避免强夯时"弹簧土"现象的发生,从而提高了最佳夯击能。复式负压固结技术可以有效地应用于新吹填软土地基。     

环境规制和农业科技进步的关系分析——基于波特假说的研究

波特假说主要从动态的角度论证了环境规制和农业科技进步之间的正向变亿关系.而在安徽省1990 -2008年的农业生产数据的基础上,选择合适的环境规制和农业科技进步的指标变量,运用Johansen协整分析方法验证了安徽省农业生产中的环境规制和农业科技进步的关系也符合这一假说,Granger因果关系检验说明了安徽省环境规制是农业科技进步产生的原因,脉冲响应分析和方差分析则更深入地从定量的角度分析了环境规制对农业科技进步影响滞后的趋势和影响程度.由实证分析可以看出,只是从静态角度来分析,环境规制是不利于农业的科技进步的;但从长期效益来看,环境规制有利于农业的科技进步.因此,在农业生态环境恶化的形势下,严格对农业废弃物的排放限制,制定较严格的农产品生产标准和产品质量标准,提高农民的环境意识和科技意识,通过强化环境规制来促使农业生产者提高农业生产技术,提高农产品品质和产品的市场竞争力就显得尤为重要.     

中国城镇化与土地集约利用关系的动态计量分析

在测度城镇化与土地集约利用的基础上,运用动态计量经济模型探讨城镇化与土地集约利用的相互作用。研究结果表明：（1）城镇化与土地集约利用均为一阶单整序列;（2）城镇化与土地集约利用之间存在长期均衡关系,但短期内却存在失衡,短期波动向长期均衡趋近的调整幅度达到18.98%;（3）城镇化是土地集约利用的Granger原因,而反向关系得不到实证支持;（4）土地集约利用对来自城镇化的冲击响应强烈,城镇化的冲击对土地集约利用的解释水平达到了90%,而城镇化对来自土地集约利用的冲击响应较弱,土地集约利用的冲击对城镇化的解释水平仅为3%。因此,应采取长期而非短期的策略,有序推进城镇化进程,加强土地利用监督管理,不断提高土地资源集约利用水平     

环鄱阳湖区水足迹的动态变化评价

水足迹模型是计量水资源承载力的一个较新颖且日趋成熟的方法。水资源状况对鄱阳湖区生态系统的平衡、稳定以及生态系统良性循环有着重要意义。将水足迹模型运用于环鄱阳湖区进行实证研究,通过计量模型计算出环鄱阳湖区1989~2008年水足迹的时间序列值,并评价其承载状况。结果显示,近20 a来,环鄱阳湖区的水足迹需求由1989年的735亿m3增加至2008年的110亿m3,呈现出波动上升趋势。至今为止水足迹未超载,但盈余空间呈减少趋势。最后从优化水资源利用、倡导绿色消费和促进区域间贸易交流等降低水足迹的需求和增大水足迹供给的角度提出了提高水足迹承载力的对策。进而从水足迹的角度为环鄱阳湖区提高生态系统承载力提供理论依据,促进江西省鄱阳湖生态经济区的建设