46,XY/47,XY,+ 17p+ mosaicism in amniocytes associated with fetal abnormalities despite normal fetal blood karyotype

46,XY/47,XY, + 17p + mosaicism was found in two primary amniotic fluid cultures (AFCs). Fetal blood karyotype was normal, but ultrasonography revealed Dandy-Walker malformation and bilateral choroid plexus cysts. Following termination of pregnancy, fetal examination revealed post-axial polydactyly and neuroblastoma-in-situ affecting both adrenals in addition to the cerebellar abnormalities. Mosaicism for the aberrant cell line was confirmed in all fetal tissues sampled and in the placenta.     

Small island developing states and sustainable development of ocean resources

Because of their economic and environmental vulnerability, small island developing states (SIDS) have peculiar developmental problems that severely affect their ability to implement the measures necessary for attaining sustainable development as recommended in UNCED's Agenda 21. Although this has been recognised by the Commission on Sustainable Development (CSD), and although there has been international acceptance of a SIDS Programme of Action (POA), SIDS have not been the focus of adequate attention by international and donor agencies. As a result, progress toward implementing the POA has been disappointing. This study examines the question of how sustainable management and development of ocean resources can contribute significantly to the achievement of the objectives of the SIDS POA.