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Chavidi Venkata Prasad Bala Yerri Swamy Chanda Lakshmi Narayana Reddy Kokkarachedu Vara Prasad Posa Sudhakara MCS Subha Song Jung Il Kashay Chowdoji Rao 《Journal of Polymers and the Environment》2012,20(2):344-352
Novel type of highly swollen beads were prepared by grafting 2-hydroxyethylacrylate onto biodegradable Sodium alginate (SA) via free-radical polymerization using potassium persulphate as an initiator and Triprolidine hydrochloride as a model drug. Evidence of grafting was obtained by fourier transform infrared spectroscopic technique. Morphological properties of the beads were studied by SEM analysis. Thermal properties and crystallinity of the beads were characterized using differential scanning calorimetry and thermogravimetric analysis and X-ray diffraction techniques, respectively. Dissolution experiments were performed to study the release profiles at 37?°C in phosphate buffer solution (pH-7.4). Effect of monomer content, crosslinking agent and drug/polymer ratio on swelling properties and release profiles were also comparatively studied. A dissolution result concludes that drug release decreases with increasing crosslinker content. The highest release (96%) was obtained for the beads prepared with 0.5?mL crosslinking agent. Equilibrium swelling degree also supports the drug release profiles confirming SA-g-HEA beads showed better release profiles compare to plain SA beads. 相似文献
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S. Subha Anand K. J. Anju Dayana Mathew M. Dileep Kumar 《Environmental monitoring and assessment》2014,186(2):719-724
Processes in natural waters are highly variable in time and space. Although changes are expected in short-time scales, how short one could get to measure reliably is subjective to sampling strategies and methodologies. Here, we show that sub-hourly changes in surface waters dissolved oxygen, nutrients, and pigments are measurable and significant in an estuarine system. Tidal circulation has been found to strongly influence the observed changes and has implications to material fluxes in and out of estuaries. 相似文献
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Sasi Subha Rayaroth Manoj P. Aravindakumar Charuvila T. Aravind Usha K. 《Environmental science and pollution research international》2021,28(26):34167-34186
Environmental Science and Pollution Research - Extensive use of surfactants in numerous fields resulted in their discharge into various environmental compartments including soil, sediment, and... 相似文献
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Bala Yerri Swamy Chavidi Venkata Prasad M. N. Prabhakar Kashay Chowdoji Rao M. C. S. Subha Ildoo Chung 《Journal of Polymers and the Environment》2013,21(4):1128-1134
Chitosan-g-poly(methacrylamide) (CS-g-PMAAm) was synthesized by redox polymerization. The synthesized graft copolymers were used to prepare microspheres (MS) by water/oil (W/O) emulsion technique and cross-linked with glutaraldehyde (GA). Developed microspheres were encapsulated using enalapril maleate (ENAM) as a model drug (hypertension) and characterized by fourier transform infrared spectroscopy, differential scanning calorimetry and scanning electron microscopy. The physico-chemical properties of the microspheres were studied by calculating drug entrapment efficiency, and drug release kinetics. % of encapsulation efficiency (% EE) increased with increase in drug loading and methacrylamide (MAAm) content. The minimum % EE (65.2 ± 1.6) was observed in case of microsphere containing 40 % MAAm, 5 % ENAM and 10 mL glutaraldehyde. The release profiles indicate that formulation containing highest (10 mL) crosslinking agent microspheres has the slow release. 相似文献
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