排序方式: 共有6条查询结果,搜索用时 15 毫秒
1
1.
2.
3.
Koji Yachiguchi Noriko Matsumoto Yuki Haga Motoharu Suzuki Chisato Matsumura Masahiro Tsurukawa Toshihiro Okuno Takeshi Nakano Kimi Kawabe Kei-ichiro Kitamura Akira Toriba Kazuichi Hayakawa Vishwajit S. Chowdhury Masato Endo Atsuhiko Chiba Toshio Sekiguchi Masaki Nakano Yoshiaki Tabuchi Takashi Kondo Shigehito Wada Hiroyuki Mishima Atsuhiko Hattori Nobuo Suzuki 《Environmental science and pollution research international》2014,21(10):6365-6372
To analyze the effect of polychlorinated biphenyl (PCB) 118 on fish bone metabolism, we examined osteoclastic and osteoblastic activities, as well as plasma calcium levels, in the scales of PCB (118)-injected goldfish. In addition, effect of PCB (118) on osteoclasts and osteoblasts was investigated in vitro. Immature goldfish, in which the endogenous effects of sex steroids are negligible, were used. PCB (118) was solubilized in dimethyl sulfoxide at a concentration of 10 ppm. At 1 and 2 days after PCB (118) injection (100 ng/g body weight), both osteoclastic and osteoblastic activities, and plasma calcium levels were measured. In an in vitro study, then, both osteoclastic and osteoblastic activities as well as each marker mRNA expression were examined. At 2 days, scale osteoclastic activity in PCB (118)-injected goldfish increased significantly, while osteoblastic activity did not change significantly. Corresponding to osteoclastic activity, plasma calcium levels increased significantly at 2 days after PCB (118) administration. Osteoclastic activation also occurred in the marker enzyme activities and mRNA expressions in vitro. Thus, we conclude that PCB (118) disrupts bone metabolism in goldfish both in vivo and in vitro experiments. 相似文献
4.
Wang Juntao Li Wenhua Nozomu Mishima Adachi Tsuyoshi 《Journal of Material Cycles and Waste Management》2021,23(5):1765-1776
Journal of Material Cycles and Waste Management - Different deposit–refund systems are being practically applied to promote the proper treatment of end-of-life products in China. One is... 相似文献
5.
Makoto Uchino Yoshiya Tanaka Yukio Ando Toshiro Yonehara Akio Hara Isao Mishima 《Journal of environmental science and health. Part. B》2013,48(5):699-715
Abstract To elucidate the neurologic features of chronic Minamata disease, and the incidence of complications with aging, we studied 80 patients with documented Minamata disease (organic mercury poisoning) from 1986 to 1994 (mean age: 63 years). Of the cardinal neurologic findings, sensory impairment was seen with highest frequency in 98.8% of patients limited to the extremities in 86.3%. Impairment of lower extremity coordination was observed in 60%, constriction of the visual field in 51.9%, and retrocochlear hearing loss in 41%. To assess age‐related complications, patients were separated into three groups by age: Group I (10 to 39 years); Group II (40 to 69 years); Group III (≥7 0 years). The incidences of hypertension and cerebrovascular diseases, organic ophthalmologic disorders (including cataracts), presbyacusis, and cervical spondylosis deformans increased significantly with age. Compared with a preceding survey (1981 to 1985, 171 patients, mean age: 63.5 years), the incidences of complicated hypertension and cataracts had decreased, whereas those of cerebrovascular disease and retinitis pigmentosa remained unchanged. The incidences of abnormal brain computed tomography (CT), presbyacusis, cervical spondylosis deformans, and positive tests for urine sugar also increased. The incidences of these complications other than retinitis pigmentosa were similar to those in the general population. These results accurately reflect the recent epidemiological disease tendencies in Japan toward a decreased incidence of hypertension and an increased incidence of diabetes. 相似文献
6.
Shibata Hideaki Galloway James N. Leach Allison M. Cattaneo Lia R. Cattell Noll Laura Erisman Jan Willem Gu Baojing Liang Xia Hayashi Kentaro Ma Lin Dalgaard Tommy Graversgaard Morten Chen Deli Nansai Keisuke Shindo Junko Matsubae Kazuyo Oita Azusa Su Ming-Chien Mishima Shin-Ichiro Bleeker Albert 《Ambio》2017,46(2):129-142
Ambio - Nitrogen (N) management presents a sustainability dilemma: N is strongly linked to energy and food production, but excess reactive N causes environmental pollution. The N footprint is an... 相似文献
1