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A. Leonard M. Duverger-Van Bogaert A. Bernard M. Lambotte-Vandepaer R. Lauwerys 《Environmental monitoring and assessment》1985,5(4):369-384
The short-term tests performed in vitro on different systems, from phage to human cells, or in vivo, on laboratory animals, allow only a qualitative estimate of the action of mutagenic agents, and the extrapolation of such experimental results to man may encounter many difficulties.Direct biomonitoring of populations exposed to chemicals could represent a more realistic approach for an evaluation of the hazards to man. Certain methods are still under development. Nevertheless, other ones can already by used routinely, e.g. the cytogenetic observations on peripheral blood lymphocytes and the Ames test for mutagenic substances in urine, and can provide useful suggestions how to set threshold limits for chemical substances encountered in the working environment. 相似文献
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中国环境镉接触人群低骨密度及肾功能不全的研究 总被引:19,自引:0,他引:19
25年前,Ambio曾载文提出应警惕环境镉污染引起的健康效应.1998年在中国进行了这方面的研究,评价了因食用大米而接触镉人群的前臂骨密度(BMD)和肾功能,发现尿镉(CdU)或血镉(CdB)高的绝经后妇女及血镉(CdB)高的男性,BMD均有所下降.在CdB或CdU与肾功能不全(视黄醇结合蛋白排泄增加)之间也发现了明显的、有统计学意义的剂量-效应关系及剂量-反应关系.第一次报道了日本以外的亚洲地区镉接触人群中存在骨不良效应.本文的意义在于阐明了亚洲的环境镉接触人群中仍存在着与肾和骨(镉的比较严重的有害效应)的联合效应,也讨论了一些欧洲镉接触人群的骨效应. 相似文献
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Bernard Barraqué 《Natural resources forum》2003,27(3):200-211
The article contributes to a discussion on two global issues on water: water resources management, and water supply and sanitation. Focusing on Europe, it traces the legal roots of current systems in history: as a resource, water is considered as a common property, rather than a market good; while as a public service it is usually a commodity. Public water supply and sanitation technologies and engineering have developed under three main paradigms: quantitative and civil engineering; qualitative and chemical/sanitary engineering (both on the supply side); and the most recent one, environmental engineering and integrated management (on the demand side). The cost of public drinking water is due to rise sharply in view of the two‐fold financial challenge of replacing an ageing infrastructure and keeping up with ever‐rising environmental and sanitary quality standards. Who will pay? Government subsidies, or water users? The author suggests that apparent successes with privatisation may have relied heavily on hidden government subsidies and/or the healthy state of previously installed water infrastructure: past government subsidies are still felt for as long as the lifetime of the infrastructure. The article stresses the importance of public participation and decentralized local management of water and sanitation services. Informing and involving users in water management decisions is seen as an integral part of the ‘ethics’ side of the crucial three E's (economics, environment, ethics). The article strongly argues for municipal provision of water services, and hopes that lessons learnt and solutions found in the European experience may serve water services management efforts in other regions of the world. 相似文献
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Phillip Drinkaus Donald S Bloswick Richard Sesek Clay Mann Thomas Bernard 《International journal of occupational safety and ergonomics》2005,11(2):141-152
This paper explores 2 methods of modifying the Strain Index (SI) to assess the ergonomic risk of multi-task jobs. Twenty-eight automotive jobs (15 cases and 13 controls) were studied. The first method is based on the maximum task SI score, and the second method is modeled on the NIOSH Composite Lifting Index (CLI) algorithm, named cumulative assessment of risk to the distal upper extremity (CARD). Significant odds ratios of 11 (CI 1.7-69) and 24 (CI 2.4-240) were obtained using the modified maximum task and CARD, respectively. This indicates that modification of the SI may be useful in determining the risk of distal upper extremity injury associated with a multi-task job. 相似文献
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Céline Jézéquel Pablo A. Tedesco William Darwall Murilo S. Dias Renata G. Frederico Max Hidalgo Bernard Hugueny Javier Maldonado-Ocampo Koen Martens Hernan Ortega Gislene Torrente-Vilara Jansen Zuanon Thierry Oberdorff 《Conservation biology》2020,34(4):956-965
Conserving freshwater habitats and their biodiversity in the Amazon Basin is a growing challenge in the face of rapid anthropogenic changes. We used the most comprehensive fish-occurrence database available (2355 valid species; 21,248 sampling points) and 3 ecological criteria (irreplaceability, representativeness, and vulnerability) to identify biodiversity hotspots based on 6 conservation templates (3 proactive, 1 reactive, 1 representative, and 1 balanced) to provide a set of alternative planning solutions for freshwater fish protection in the Amazon Basin. We identified empirically for each template the 17% of sub-basins that should be conserved and performed a prioritization analysis by identifying current and future (2050) threats (i.e., degree of deforestation and habitat fragmentation by dams). Two of our 3 proactive templates had around 65% of their surface covered by protected areas; high levels of irreplaceability (60% of endemics) and representativeness (71% of the Amazonian fish fauna); and low current and future vulnerability. These 2 templates, then, seemed more robust for conservation prioritization. The future of the selected sub-basins in these 2 proactive templates is not immediately threatened by human activities, and these sub-basins host the largest part of Amazonian biodiversity. They could easily be conserved if no additional threats occur between now and 2050. 相似文献
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Simon?BrinerEmail author Michael?Hartmann Robert?Finger Bernard?Lehmann 《Mitigation and Adaptation Strategies for Global Change》2012,17(4):337-355
We assessed the economic suitability of 4 greenhouse gas (GHG) mitigation options and one GHG offset option for an improvement
of the GHG balance of a representative Swiss suckler cow farm housing 35 Livestock units and cultivating 25 ha grassland.
GHG emissions per kilogram meat in the economic optimum differ between the production systems and range from 18 to 21.9 kg
CO2-eq./kg meat. Only GHG offset by agroforestry systems showed the potential to significantly reduce these emissions. Depending
on the production system agroforestry systems could reduce net GHG emissions by 66% to 7.3 kg CO2-eq./kg meat in the most intensive system and by 100% in the most extensive system. In this calculation a carbon sequestration
rate of 8 t CO2/ha/year was assumed. The potential of a combination of the addition of lipids to the diet, a cover of the slurry tank and
the application of nitrification inhibitors only had the potential to reduce GHG emissions by 12% thereby marginal abatement
costs are increasing much faster than for agroforestry systems. A reduction of the GHG emissions to 7.5 kg CO2-eq./kg meat—possible with agroforestry only—raised costs between 0.03 CHF/kg meat and 0.38 CHF/kg meat depending on the production
system and the state of the system before the reduction. If GHG emissions were reduced maximally average costs ranged between
0.37 CHF/kg meat, if agroforestry had the potential to reduce net GHG emissions to 0 kg CO2-eq., to 1.17 CHF/kg meat if also other options had to be applied. 相似文献
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OBJECTIVE: To determine whether DUI offenders can better avoid future drinking and driving by controlling their vehicle usage rather than by controlling their drinking. METHODS: Using a randomized experimental post-test only design, 9,571 first-time DUI offenders were randomly assigned to receive one of two 12-hour educational programs: a traditional DUI curriculum or the PARC (Preventing Alcohol-Related Convictions) curriculum, which uses a novel theoretical approach to preventing DUI recidivism. Whereas traditional programs focus on participants controlling their drinking to avoid future drinking and driving, the PARC curriculum focuses on participants controlling their driving. Instead of trying to control alcohol consumption after driving to a drinking venue (previously found to be a flawed strategy), PARC teaches students to make a decision before leaving home not to drive to a drinking event, thus greatly limiting the possibility of drinking and driving. Driving records were obtained from the Florida Department of Motor Vehicles using driver's license numbers to assess DUI recidivism rates among the students in the PARC and Traditional curricula for the first year following program participation and again at 2 years post-intervention. RESULTS: Binary logistic regression analyses revealed that offenders receiving the PARC curriculum exhibited significantly lower 1-year and 2-year recidivism rates than those receiving the Traditional curriculum. The effect was consistent across two different measures of recidivism, and across gender, race, ethnicity, and location. CONCLUSION: Results suggest that the PARC educational approach may be more effective than the traditional approach in reducing DUI recidivism. 相似文献