In this paper, a procedure for analyzing a water resource system with special emphasis on evaluation of acceptable economic risk due to occasional failures to deliver water is proposed. The basic methodology includes the development of a simple mathematical model which describes the physical hydrologic and economic characteristics of a single reservoir irrigation and city water supply system and an evaluation of economic benefits of the system with full and partial deliveries of water. The system is simulated for various combinations of decision variables (system magnitudes) and an optimum design is obtained by response surface technology. Emphasis is placed on the basic model and methodology although, in order to introduce some realism, the procedure is applied to data based on the existing reservoir system on the South Concho River in West Central Texas. 相似文献
Multimetric indices based on fish and benthic macroinvertebrate assemblages are commonly used to assess the biological integrity
of aquatic ecosystems. However, their response to specific stressors is rarely known. We quantified the response of a fish-based
index (Mid-Atlantic Highlands Index of Biotic Integrity, MAH-IBI) and a benthic invertebrate-based index (West Virginia Stream
Condition Index, WV-SCI) to acid mine drainage (AMD)-related stressors in 46 stream sites within the Cheat River watershed,
West Virginia. We also identified specific stressor concentrations at which biological impairment was always or never observed.
Water chemistry was extremely variable among tributaries of the Cheat River, and the WV-SCI was highly responsive across a
range of AMD stressor levels. Furthermore, impairment to macroinvertebrate communities was observed at relatively low stressor
concentrations, especially when compared to state water quality standards. In contrast to the WV-SCI, we found that the MAH-IBI
was significantly less responsive to local water quality conditions. Low fish diversity was observed in several streams that
possessed relatively good water quality. This pattern was especially pronounced in highly degraded subwatersheds, suggesting
that regional conditions may have a strong influence on fish assemblages in this system. Our results indicate that biomonitoring
programs in mined watersheds should include both benthic invertebrates, which are consistent indicators of local conditions,
and fishes, which may be indicators of regional conditions. In addition, remediation programs must address the full suite
of chemical constituents in AMD and focus on improving linkages among streams within drainage networks to ensure recovery
of invertebrate and fish assemblages. Future research should identify the precise chemical conditions necessary to maintain
biological integrity in mined Appalachian watersheds. 相似文献
Amniocentesis was performed in view of a paternal balanced chromosomal rearrangement t(4;20)(p16;p12), inv(18)(p11q11). The pregnancy was complicated by severe oligohydramnios. The fetal karyotype was unbalanced: 46XX, der(4), t(4;20)(p16;p12), inv(18) (p11q11)pat., thus resulting in partial trisomy 2Op and monosomy 4p. In addition, the amniotic fluid alpha-fetoprotein (AFP) became increasingly elevated with gestational age. The pregnancy was terminated at 25 weeks. The fetus presented with typical facial dysmorphic features, unilateral cleft lip and palate, severe renal hypoplasia, consistent with the 4p- (Wolf-Hirschhorn) syndrome. 相似文献
Objectives: This study examined a multicommunity alternative transportation program available 24 hours a day, 7 days a week, for any purpose, offering door-through-door service in private automobiles to members who either do not drive or are transitioning away from driving. Specific aims were to describe the characteristics of members by driving status and ride service usage of these members.
Methods: Data came from administrative records maintained by a nonprofit ride service program and include 2,661 individuals aged 65+ residing in 14 states who joined the program between April 1, 2010, and November 8, 2013. Latent class analysis was used to group current drivers into 3 classes of driving status of low, medium, and high self-regulation, based on their self-reported avoidance of certain driving situations and weekly driving frequency. Demographics and ride service use rate for rides taken through March 31, 2014, by type of ride (e.g., medical, social, etc.) were calculated for nondrivers and drivers in each driving status class.
Results: The majority of ride service users were female (77%) and aged 65–74 years (82%). The primary method of getting around when enrolling for the transportation service was by riding with a friend or family member (60%). Among the 67,883 rides given, nondrivers took the majority (69%) of rides. Medical rides were the most common, accounting for 40% of all rides.
Conclusions: Reported ride usage suggests that older adults are willing to use such ride services for a variety of trips when these services are not limited to specific types (e.g., medical). Further research can help tailor strategies to encourage both nondrivers and drivers to make better use of alternative transportation that meets the special needs of older people. 相似文献
The X-linked Hunter syndrome or mucopolysaccharidosis II was diagnosed in a male fetus by demonstrating a severe deficiency of iduronate 2-sulphate sulphatase activity in fetal plasma obtained by umbilical fetal blood sampling at 23 weeks of pregnancy. The diagnosis was confirmed after termination of pregnancy. 相似文献