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N. Anger B. Brouns J. Onigkeit 《Mitigation and Adaptation Strategies for Global Change》2009,14(5):379-398
We investigate the role of domestic allowance allocation and global emissions constraints for the carbon-market impacts of
linking the EU Emissions Trading Scheme (ETS) internationally. Employing a quantitative simulation model of the global carbon
market, we find that the economic benefits from connecting the European ETS to emerging non-EU schemes strongly depend on
the regional allowance allocation of the linking participants: In a world of moderate carbon constraints, an economically
efficient regional allowance allocation induces a much stronger fall in total compliance costs than a sub-optimal (i.e. too
high) domestic allocation of emissions permits. However, a more efficient (i.e. stricter) allocation shifts abatement efforts
and compliance costs to energy-intensive industries which are covered by the domestic ETS. We further find that committing
to ambitious global emissions reduction targets (compatible with stabilizing CO2 concentrations at 450 ppm) induces much stronger regional abatement efforts and substantially higher compliance costs for
the abating regions. In such an ambitious climate policy regime, an efficient domestic allocation of allowances is even more
important from an economic perspective: Here, linking emissions trading schemes diminishes the associated compliance costs
on the largest scale.
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J. OnigkeitEmail: |
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Moens LN Smolders R van der Ven K van Remortel P Del-Favero J De Coen WM 《Chemosphere》2007,67(11):2293-2304
Effluents are a main source of direct and continuous input of pollutants to the aquatic environment, and can cause ecotoxicological effects at different levels of biological organization. Since gene expression responses represent the primary interaction site between environmental contaminants and biota, they provide essential clues to understand how chemical exposure can affect organismal health. The aim of the present study was to investigate the applicability of a microarray approach for unraveling modes of action of whole effluent toxicity and impact assessment. A chronic toxicity test with common carp (Cyprinus carpio) was conducted where fish were exposed to a control and 100% effluent for 21 days under flow-through conditions. Microarray analysis revealed that effluent treatment mainly affected molecular pathways associated with the energy balance of the fish, including changes in carbohydrate and lipid metabolism, as well as digestive enzyme activity. These gene expression responses were in clear agreement with, and provided additional mechanistic information on various cellular and higher level effects observed for the same effluent. Our results demonstrate the benefit of toxicogenomic tools in a “systems toxicology” approach, involving the integration of adverse effects of chemicals and stressors across multiple levels of biological complexity. 相似文献
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Effects of the antidepressant mianserin in zebrafish: molecular markers of endocrine disruption 总被引:1,自引:0,他引:1
van der Ven K Keil D Moens LN Hummelen PV van Remortel P Maras M De Coen W 《Chemosphere》2006,65(10):1836-1845
Due to their environmental occurrence and intrinsic biological activity, human pharmaceuticals have received increasing attention from environmental and health agencies. Of particular, ecotoxicological concern are drugs that affect nervous- and endocrine-systems. Zebrafish genome-wide oligo arrays are used to collect mechanistic information on mianserin-induced changes in gene expression in zebrafish. Gene expression analysis in brain and gonad tissue clearly demonstrated the estrogenic activity of mianserin and its potency to disrupt normal endocrine (estrogenic) signaling, based on induction of molecular biomarkers of estrogenicity (e.g., vitellogenin1 and zona pellucida proteins). The possible mechanism underlying this estrogenic activity of mianserin is disturbance of the Hypothalamo-Pituitary-Gonadal (HPG) axis by direct interference of mianserin with the serotonergic and adrenergic systems in the brain of zebrafish. Taking into account the importance of the HPG-axis, and considering the concept of 'critical window of exposure', our results reveal the importance for more elaborate testing of endocrine disruptive effects of aquatic antidepressants at different lifestages and during longer exposure periods (e.g., life cycle studies). Although there is a low concordance between the gene expression results in this study and previous cDNA microarray hybridizations, the global mechanistic expression patterns are similar in both platforms. This argues in favor of pathway-driven analysis of gene expression results compared to gene-per-gene analysis. 相似文献
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Rodney S. Skeen Stuart P. Luttrell Thomas M. Brouns Brian S. Hooker James N. Petersen 《补救:环境净化治理成本、技术与工艺杂志》1993,3(3):353-367
The U.S. Department of Energy has generated liquid wastes containing radioactive and hazardous chemicals throughout the more than forty years of operation at its Hanford site in Washington State. Many of the waste components, including nitrate and carbon tetrachloride (CCl4), have been detected in the Hanford groundwater. In-situ bioremediation of CCl4 and nitrate is being considered to clean the aquifer. Preliminary estimates indicate that this technology should cost significantly less than ex-situ bioremediation and about the same as air stripping/granular activated carbon. In-situ bioremediation has the advantage of providing ultimate destruction of the contaminant and requires significantly less remediation time. Currently, a test site is under development. A computer-aided design tool is being used to design optimal remediation conditions by linking subsurface transport predictions, site characterization data, and microbial growth and contaminant destruction kinetics. 相似文献
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In recent years growing attention has been paid toward the discharge, presence and potential adverse effects of pharmaceuticals in the environment. Using different existing analytical methods several studies have already identified a variety of drugs in waste-, surface- and drinking water. The monitoring of surface waters for drugs is of great importance because drugs are designed to be biological very active substances. A capillary LC/ES-MS-MS method has been developed that enables the sensitive and specific detection of diazepam in water samples up to 0.1 ng/ml (LOD). It requires neither multiple extraction steps, nor the use of large volumes of organic solvent. Applying this assay we have detected diazepam in 'in/effluent samples' collected in Belgium and demonstrated the applicability for water analysis without off-line pre-concentration of the analyte. 相似文献
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J. Onigkeit N. Anger B. Brouns 《Mitigation and Adaptation Strategies for Global Change》2009,14(5):477-494
Climate equity is a crucial but difficult element in negotiations on a post-2012 climate regime. With respect to the trading
of greenhouse gas emissions the equity aspect is considered in the Kyoto Protocol which demands that emissions trading should
be supplemental to domestic abatement efforts. The question arises whether a linking of the European Union Emissions Trading
Scheme (EU ETS) to non-EU emission trading schemes or the Clean Development Mechanism (CDM) could have an impact on principles
of climate justice and thus potentially affect ongoing negotiations. In this study, we present the results of a three step
analysis: In a first step, it estimates mid-term greenhouse gas emission entitlements for Annex B and Non-Annex B countries
for the year 2020 which keep within reach a stabilization of the CO2 concentration at 450 ppmv in the long-term. In the second step, the resulting emission entitlements are used as an input
to an economic partial-equilibrium model in order to assess the shift of abatement efforts under different scenarios of linking
the EU ETS. In a third step, we analyze the outcome of the economic model with respect to the future trend of European per
capita emissions under the current EU ETS relative to different scenarios of linking the EU ETS. The model results indicate
that European per capita emissions have to be reduced to a considerably smaller extent if a linking of the EU ETS is accompanied
by an optimal design of the National Allocation Plans and if low-cost CO2 permits became available via the CDM to a large extent.
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B. BrounsEmail: |
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Soetaert A van der Ven K Moens LN Vandenbrouck T van Remortel P De Coen WM 《Chemosphere》2007,67(1):60-71
In the present study, the existing life stage-specific cDNA library was extended with energy- and molting-related genes using Suppression Subtractive Hybridization PCR and a microarray for the aquatic test organism Daphnia magna was created. A gene set of 2455 fragments was produced belonging to different pathways such as carbohydrate and lipid metabolism, O2 transport and heme metabolism, immune response, embryo development, cuticula metabolism and visual perception pathways. Using this custom microarray, gene expression profiles were generated from neonates exposed to three concentrations of the anti-ecdysteroidal fungicide fenarimol (0.5, 0.75, 1 microg/ml) during 48 h and 96 h. In total, 59 non-redundant genes were differentially expressed, of which more genes were down- than up-regulated. The gene expression data indicated a main effect on molting specific pathways. At the highest concentration, a set of proteolytic enzymes - including different serine proteases and carboxypeptidases - were induced whereas different cuticula proteins were down-regulated (48 h). Moreover, effects on embryo development were demonstrated at the gene expression as well as at the organismal level. The embryo development related gene vitellogenin was differentially expressed after 96 h of exposure together with a significant increase in embryo abnormalities in the offspring. This study suggests that this Daphnia magna microarray is of great further value for the elucidation of molecular mechanisms of toxicity and for the future development of specific biomarkers for hazard characterization. 相似文献
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