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Kornelia Zemke Axel Liebscher Maren Wandrey the COSINKGroup 《International Journal of Greenhouse Gas Control》2010,4(6):990-999
To test the injection behaviour of CO2 into brine-saturated rock and to evaluate the dependence of geophysical properties on CO2 injection, flow and exposure experiments with brine and CO2 were performed on sandstone samples of the Stuttgart Formation representing potential reservoir rocks for CO2 storage. The sandstone samples studied are generally fine-grained with porosities between 17 and 32% and permeabilities between 1 and 100 mD.Additional batch experiments were performed to predict the long-term behaviour of geological CO2 storage. Reservoir rock samples were exposed over a period of several months to CO2-saturated reservoir fluid in high-pressure vessels under in situ temperature and pressure conditions. Petrophysical parameters, porosity and the pore radius distribution were investigated before and after the experiments by NMR (Nuclear Magnetic Resonance) relaxation and mercury injection. Most of the NMR measurements of the tested samples showed a slight increase of porosity and a higher proportion of large pores. 相似文献
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Chantal Deden Kornelia Neveling Dimitra Zafeiropopoulou Christian Gilissen Rolph Pfundt Tuula Rinne Nicole de Leeuw Brigitte Faas Thatjana Gardeitchik Suzanne C. E. H. Sallevelt Aimee Paulussen Servi J. C. Stevens Esther Sikkel Mariet W. Elting Merel C. van Maarle Karin E. M. Diderich Nicole Corsten-Janssen Klaske D. Lichtenbelt Guus Lachmeijer Lisenka E. L. M. Vissers Helger G. Yntema Marcel Nelen Ilse Feenstra Wendy A. G. van Zelst-Stams 《黑龙江环境通报》2020,40(8):972-983
Objective
The purpose of this study was to explore the diagnostic yield and clinical utility of trio-based rapid whole exome sequencing (rWES) in pregnancies of fetuses with a wide range of congenital anomalies detected by ultrasound imaging.Methods
In this observational study, we analyzed the first 54 cases referred to our laboratory for prenatal rWES to support clinical decision making, after the sonographic detection of fetal congenital anomalies. The most common identified congenital anomalies were skeletal dysplasia (n = 20), multiple major fetal congenital anomalies (n = 17) and intracerebral structural anomalies (n = 7).Results
A conclusive diagnosis was identified in 18 of the 54 cases (33%). Pathogenic variants were detected most often in fetuses with skeletal dysplasia (n = 11) followed by fetuses with multiple major fetal congenital anomalies (n = 4) and intracerebral structural anomalies (n = 3). A survey, completed by the physicians for 37 of 54 cases, indicated that the rWES results impacted clinical decision making in 68% of cases.Conclusions
These results suggest that rWES improves prenatal diagnosis of fetuses with congenital anomalies, and has an important impact on prenatal and peripartum parental and clinical decision making. 相似文献4.
Kotzerke A Sharma S Schauss K Heuer H Thiele-Bruhn S Smalla K Wilke BM Schloter M 《Environmental pollution (Barking, Essex : 1987)》2008,153(2):315-322
Most veterinary drugs enter the environment via manure application. However, it is unclear how these substances interact with soil biota. Therefore, it was the aim of the present study to investigate the effects of manure containing different concentrations of the antibiotic sulfadiazine (SDZ) on the soil microbial communities. It was shown that manure alone has a stimulating effect on microbial activity. Only potential nitrification was negatively influenced by manure application. The addition of SDZ to the manure reduced microbial activity. Depending on the SDZ concentration, levels of activity were in the range of the control soil without manure application. Also, selected processes in nitrogen turnover were negatively influenced by the addition of SDZ to the manure, with nitrification being the only exception. The effects were visible for up to 4 days after application of the manure with or without SDZ and were correlated with the bioavailability of the antibiotic. 相似文献
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