A system-based approach to the genetic etiologies of non-immune hydrops fetalis

A wide spectrum of genetic causes may lead to nonimmune hydrops fetalis (NIHF), and a thorough phenotypic and genetic evaluation are essential to determine the underlying etiology, optimally manage these pregnancies, and inform discussions about anticipated prognosis. In this review, we outline the known genetic etiologies of NIHF by fetal organ system affected, and provide a systematic approach to the evaluation of NIHF. Some of the underlying genetic disorders are associated with characteristic phenotypic features that may be seen on prenatal ultrasound, such as hepatomegaly with lysosomal storage disorders, hyperechoic kidneys with congenital nephrosis, or pulmonary valve stenosis with RASopathies. However, this is not always the case, and the approach to evaluation must include prenatal ultrasound findings as well as genetic testing and many other factors. Genetic testing that has been utilized for NIHF ranges from standard chromosomal microarray or karyotype to gene panels and broad approaches such as whole exome sequencing. Family and obstetric history, as well as pathology examination, can yield additional clues that are helpful in establishing a diagnosis. A systematic approach to evaluation can guide a more targeted approach to genetic evaluation, diagnosis, and management of NIHF.     

Maternal genetic disorders and fetal development

With improvements in early diagnosis and management of genetic diseases, more women with genetic disorders are reaching reproductive age and becoming pregnant. While pregnancy can have a significant impact on a woman's health when there is an underlying genetic disorder, there can also be fetal effects, including embryopathy, fetal growth restriction, and brain injury. Some maternal genetic disorders are associated with adverse perinatal outcomes, including a high risk of perinatal loss and preterm birth. In this article, we review several maternal genetic disorders associated with fetal risk that are important for clinicians and patients to understand and manage appropriately. These include phenylalanine hydroxylase (PAH) deficiency and other inborn errors of metabolism, tuberous sclerosis complex, myotonic dystrophy, cystic fibrosis, Turner syndrome, sickle cell disease, and connective tissue disorders.     

A sustainable production model for waste management with uncertain scrap and recycled material

Journal of Material Cycles and Waste Management - The studies highlightthat only one billion tons were obtained out of four billion tons of solid waste in the world and small value recovered out of...     

Algae and bacteria consortia for wastewater decontamination and transformation into biodiesel,bioethanol, biohydrogen,biofertilizers and animal feed: a review

Traditional wastewater treatment has been aimed solely at sanitation by removing contaminants, yet actual issues of climate change and depletion of natural resources are calling for methods that both remove contaminants and convert waste into chemicals and fuels. In particular, biological treatments with synergic coupling of microalgae and bacteria appear promising to remove organic, inorganic, and pathogen contaminants and to generate biofuels. Here, we review the use of algae and bacteria in the treatment and valorization of wastewater with focus on cell-to-cell adhesion, wastewater properties, and techniques for algae harvesting and production of biodiesel, bioethanol, biohydrogen, exopolysaccarides, biofertilizers, and animal feeds.

     

ZnO nanophotocatalysts coupled with ceramic membrane method for treatment of Rhodamine-B dye waste water

In the present investigation, hybrid treatment process has been developed for the treatment of synthetic dye wastewater. Photocatalysis and ceramic nanoporous membrane are mainly used for process integration to minimize the fouling and increase the flux. Commercial ZnO powder has been used as a nano-photocatalyst for the degradation of rhodamine-B dye in the hybrid system. Commercial ceramic nanoporous tubular membranes have been used for the rejection of dye and suspended catalysts. Photocatalysis process alone has shown the 33% of decolorization, whereas ceramic nanofiltration has shown the 50% of decolorization. Integration of photocatalysis and ceramic nanofiltration were shown 96% of dye decolorization over 90 min of operation.     

A promising niche: waste to energy project in the Indian dairy sector

The dairy sector is known to have significant local and global environmental impacts; but it also has proven renewable-energy generation potential. This paper analyzes a specific niche experiment in the Indian dairy industry, wherein cattle waste management is carried out by a multitude of stakeholders. These include the waste collectors, local technology adopters, research institutions, multilateral donor agencies, the Indian government, technology suppliers and operation and maintenance teams who have managed an uninterrupted 1 MWe energy production over the past 4 years. This analysis uses the sociotechnical regime framework to study the interaction of social, technological, economic and policy-related aspects relevant to the niche experiment. The analysis shows a potential to contribute to the development of two complementing regimes—one related to cooperative waste management and the other related to grid-connected renewable-energy-based electricity generation. Key factors for a successful development are not only a long-term financing protection through government subsidies to cover higher capital cost and a preferential tariff related to energy throughput, but also the adaptation of technology, the embedding in the local cooperative structure and the removal of regulatory barriers.     

Characterization of Storm Flow Dynamics of Headwater Streams in the South Carolina Lower Coastal Plain1

Epps, Thomas H., Daniel R. Hitchcock, Anand D. Jayakaran, Drake R. Loflin, Thomas M. Williams, and Devendra M. Amatya, 2012. Characterization of Storm Flow Dynamics of Headwater Streams in the South Carolina Lower Coastal Plain. Journal of the American Water Resources Association (JAWRA) 1‐14. DOI: 10.1111/jawr.12000 Abstract: Hydrologic monitoring was conducted in two first‐order lower coastal plain watersheds in South Carolina, United States, a region with increasing growth and land use change. Storm events over a three‐year period were analyzed for direct runoff coefficients (ROC) and the total storm response (TSR) as percent rainfall. ROC calculations utilized an empirical hydrograph separation method that partitioned total streamflow into sustained base flow and direct runoff components. ROC ratios ranged from 0 to 0.32 on the Upper Debidue Creek (UDC) watershed and 0 to 0.57 on Watershed 80 (WS80); TSR results ranged from 0 to 0.93 at UDC and 0.01 to 0.74 at WS80. Variability in event runoff generation was attributed to seasonal trends in water table elevation fluctuation as regulated by evapotranspiration. Groundwater elevation breakpoints for each watershed were identified based on antecedent water table elevation, streamflow, ROCs, and TSRs. These thresholds represent the groundwater elevation above which event runoff generation increased sharply in response to rainfall. For effective coastal land use decision making, baseline watershed hydrology must be understood to serve as a benchmark for management goals, based on both seasonal and event‐based surface and groundwater interactions.     

Curve Number Derivation for Watersheds Draining Two Headwater Streams in Lower Coastal Plain South Carolina,USA

The objective of this study was to assess curve number (CN) values derived for two forested headwater catchments in the Lower Coastal Plain (LCP) of South Carolina using a three‐year period of storm event rainfall and runoff data in comparison with results obtained from CN method calculations. Derived CNs from rainfall/runoff pairs ranged from 46 to 90 for the Upper Debidue Creek (UDC) watershed and from 42 to 89 for the Watershed 80 (WS80). However, runoff generation from storm events was strongly related to water table elevation, where seasonally variable evapotranspirative wet and dry moisture conditions persist. Seasonal water table fluctuation is independent of, but can be compounded by, wet conditions that occur as a result of prior storm events, further complicating flow prediction. Runoff predictions for LCP first‐order watersheds do not compare closely to measured flow under the average moisture condition normally associated with the CN method. In this study, however, results show improvement in flow predictions using CNs adjusted for antecedent runoff conditions and based on water table position. These results indicate that adaptations of CN model parameters are required for reliable flow predictions for these LCP catchments with shallow water tables. Low gradient topography and shallow water table characteristics of LCP watersheds allow for unique hydrologic conditions that must be assessed and managed differently than higher gradient watersheds.