Attitudes towards sex selection for non-medical reasons: a review

Early non-invasive fetal sexing is widely available over the Internet, leading to concerns about its possible use for sex selection. The aim of this review is to summarise the results of surveys describing lay attitudes towards sex selection for non-medical reasons to help address or inform such concerns. A search of electronic databases and key journals was supplemented by an Internet search and citation-tracking. Twenty-one quantitative studies were identified. Most were conducted in the US, with five recent studies in the UK and Germany. Most studies found that, overall, people were not in favour of sex selection. However, this varied from 94 to 18%. People may hold more negative attitudes when the method of sex selection is specified, particularly if this involves termination of pregnancy (TOP). Attitudes towards the general availability of sex selection are less negative than those towards personal use. Attitudes were consistently negative in German surveys. Little is known of such attitudes outside the US, the UK and Germany, and how such attitudes may change as new sex selection technologies become available. Studies of use of early non-invasive fetal sexing for sex selection for non-medical reasons are needed to assess the extent to which concerns about usage are justified and to assist in debates on how these might be most appropriately addressed. Copyright © 2006 John Wiley & Sons, Ltd.     

Prenatal diagnosis and post-mortem study of a fetus with mosaic trisomy 14 due to a dic(14)(p11)

Amniocentesis at 17 weeks' gestation revealed a mosaic karyotype—46,XX/46,XX, — 14,+dic(14)(p11). No abnormalities were detected on ultrasound. Growth and placentation were normal. The fetus was examined after termination of pregnancy and micrognathia and pulmonary hyperlobation were the only abnormalities detected. Several tissues were set up for cytogenetics, including fetal skin, kidney, ovary, and placenta. The diagnosis was confirmed by these studies. The level of mosaicism varied between tissues, with the trisomy 14 cell line highest in amniotic fluid.     

Use of signature whistles during separations and reunions by wild bottlenose dolphin mothers and infants

We examine the contexts and patterns of signature whistle production by wild bottlenose dolphin mother-infant pairs (Tursiops spp.) to gain insight into the functional significance of whistles. Results are based on focal observations and simultaneous recordings of underwater vocalizations. Whistles occur primarily when mother-infant pairs are separated, and the probability of whistles increases with distance of separation. The timing of whistles during separations varies, but whistles tend to be produced in repetitive series and are generally concentrated toward the later stages of the separation, i.e., during the process of reunion. Although we focused on infants, mothers do not appear to whistle during separations as frequently as infants. Infant whistles may function to facilitate reunions by conveying information to the mother concerning the infant's motivation to reunite and/or its location. Infant whistles could induce a cooperative response from the mother including approach, slowing to allow the infant to catch up or whistling. Highly individualized signature whistles may be particularly useful in a fission-fusion society in which individuals (mothers and infants as well as adults) join and leave temporary parties in a fluid manner, yet maintain consistent, long-term associations with particular individuals. Correspondence to: R.A. Smolker     

Job level risk assessment using task level strain index scores: a pilot study.

This paper explores 2 methods of modifying the Strain Index (SI) to assess the ergonomic risk of multi-task jobs. Twenty-eight automotive jobs (15 cases and 13 controls) were studied. The first method is based on the maximum task SI score, and the second method is modeled on the NIOSH Composite Lifting Index (CLI) algorithm, named cumulative assessment of risk to the distal upper extremity (CARD). Significant odds ratios of 11 (CI 1.7-69) and 24 (CI 2.4-240) were obtained using the modified maximum task and CARD, respectively. This indicates that modification of the SI may be useful in determining the risk of distal upper extremity injury associated with a multi-task job.     

Modulation-assisted high speed machining of compacted graphite iron (CGI)

The application of controlled, low-frequency modulation (～100 Hz) superimposed onto the cutting process in the feed-direction – modulation-assisted machining (MAM) – is shown to be quite effective in reducing the wear of cubic boron nitride (CBN) tools when machining compacted graphite iron (CGI) at high machining speeds (>500 m/min). The tool life is at least 20 times greater than in conventional machining. This significant reduction in wear is a consequence of the multiple effects realized by MAM, including periodic disruption of the tool–workpiece contact, formation of discrete chips, enhanced fluid action and lower cutting temperatures. The propensity for thermochemical wear of CBN, the principal wear mode at high speeds in CGI machining, is thus reduced. The tool wear in MAM is also found to be smaller at the higher cutting speeds (730 m/min) tested. The feed-direction MAM appears feasible for implementation in industrial machining applications involving high speeds.     

Genetic sex determination in <Emphasis Type="Italic">Astatotilapia calliptera</Emphasis>, a prototype species for the Lake Malawi cichlid radiation

East African cichlids display extensive variation in sex determination systems. The species Astatotilapia calliptera is one of the few cichlids that reside both in Lake Malawi and in surrounding waterways. A. calliptera is of interest in evolutionary studies as a putative immediate outgroup species for the Lake Malawi species flock and possibly as a prototype ancestor-like species for the radiation. Here, we use linkage mapping to test association of sex in A. calliptera with loci that have been previously associated with genetic sex determination in East African cichlid species. We identify a male heterogametic XY system segregating at linkage group (LG) 7 in an A. calliptera line that originated from Lake Malawi, at a locus previously shown to act as an XY sex determination system in multiple species of Lake Malawi cichlids. Significant association of genetic markers and sex produce a broad genetic interval of approximately 26 megabases (Mb) using the Nile tilapia genome to orient markers; however, we note that the marker with the strongest association with sex is near a gene that acts as a master sex determiner in other fish species. We demonstrate that alleles of the marker are perfectly associated with sex in Metriaclima mbenjii, a species from the rock-dwelling clade of Lake Malawi. While we do not rule out the possibility of other sex determination loci in A. calliptera, this study provides a foundation for fine mapping of the cichlid sex determination gene on LG7 and evolutionary context regarding the origin and persistence of the LG7 XY across diverse, rapidly evolving lineages.     

Overcoming barriers to sustainability by combining conceptual,visual, and networking systems

Sustainability challenges rarely align with the conventional boundaries of our disciplines, institutions and means of communication. To address these challenges amid real-world complexity, we need to think holistically and collaborate across disciplines. In this paper, we synthesise three themes: (1) more integrated conceptual frameworks; (2) digital visual communication which provides fluid expression of complex ideas and perceptions; and (3) online networks which can empower sustainability initiatives and communicate them across social and institutional barriers at a global scale. Each of these tools can help to overcome persistent barriers to sustainability. When used together, they provide a strategic basis for the design of digital collaboration platforms for addressing sustainability challenges. Using design thinking, we developed a Synergy Map which identifies relationships among a number of barriers to sustainability and conceptual and digital tools which help to address them. The Map identifies the potential for synthesising these tools into effective digital artefacts. We provide several examples and identify characteristics of particular value for overcoming barriers to sustainability. Combining new theoretical developments in sustainability sciences with recent advances in communication and networking technologies offers substantial potential for advancing sustainability on multiple fronts.     

Improvements to lawn and garden equipment emissions estimates for Baltimore, Maryland

Lawn and garden equipment are a significant source of emissions of volatile organic compounds (VOCs) and other pollutants in suburban and urban areas. Emission estimates for this source category are typically prepared using default equipment populations and activity data contained in emissions models such as the U.S. Environmental Protection Agency's (EPA) NONROAD model or the California Air Resources Board's (CARB) OFFROAD model. Although such default data may represent national or state averages, these data are unlikely to reflect regional or local differences in equipment usage patterns because of variations in climate, lot sizes, and other variables. To assess potential errors in lawn and garden equipment emission estimates produced by the NONROAD model and to demonstrate methods that can be used by local planning agencies to improve those emission estimates, this study used bottom-up data collection techniques in the Baltimore metropolitan area to develop local equipment population, activity, and temporal data for lawn and garden equipment in the area. Results of this study show that emission estimates of VOCs, particulate matter (PM), carbon monoxide (CO), carbon dioxide (CO2), and nitrogen oxides (NO(x)) for the Baltimore area that are based on local data collected through surveys of residential and commercial lawn and garden equipment users are 24-56% lower than estimates produced using NONROAD default data, largely because of a difference in equipment populations for high-usage commercial applications. Survey-derived emission estimates of PM and VOCs are 24 and 26% lower than NONROAD default estimates, respectively, whereas survey-derived emission estimates for CO, CO2, and NO(x) are more than 40% lower than NONROAD default estimates. In addition, study results show that the temporal allocation factors applied to residential lawn and garden equipment in the NONROAD model underestimated weekend activity levels by 30% compared with survey-derived temporal profiles.     

Framing the flood: a media analysis of themes of resilience in the 2011 Brisbane flood

In the wake of the flood that affected Brisbane, Australia, in January 2011, public attention turned to the causes of the event and lessons for minimizing the impacts of future floods. The news media was an important vehicle for understanding and internalizing the 2011 Brisbane flood. Examining how the flood was framed in the media is, therefore, useful to understand broad public perception of floods. We undertook a systematic newspaper analysis during a one-year period to explore media framings of the flood, focused on learning as an aspect of resilience in relation to two themes: (1) perceived links between the flood and climate change and (2) perceived roles of government in managing the flood. We show that media coverage of the flood reinforces aspects of resilience by acknowledging community spirit, self-reliance and the importance of sharing experiences for learning; articulating the risk of extreme events in a changing climate; and highlighting regional management trade-offs. Much of the discourse is likely to inhibit resilience, however, by casting the flood in terms of blame and political opportunity and paying inadequate attention to longer-term aspects of regional resilience. The limited learning observed to date may highlight a need for other mechanisms and actors to lead learning processes. As policy related to the 2011 Brisbane flood, and extreme events more generally, is influenced by the public discourse, it is important to understand the nuances of communication around these events and the media’s role in reinforcing or changing perceptions.     

Cesium isotope ratios as indicators of nuclear power plant operations

There are multiple paths by which radioactive cesium can reach the effluent from reactor operations. The radioactive ¹³⁵Cs/¹³⁷Cs ratios are controlled by these paths. In an effort to better understand the origin of this radiation, these ¹³⁵Cs/¹³⁷Cs ratios in effluents from three power reactor sites have been measured in offsite samples. These ratios are different from global fallout by up to six fold and as such cannot have a significant component from this source. A cesium ratio for a sample collected outside of the plant boundary provides integration over the operating life of the reactor. A sample collected inside the plant at any given time can be much different from this lifetime ratio. The measured cesium ratios vary significantly for the three reactors and indicate that the multiple paths have widely varying levels of contributions. There are too many ways these isotopes can fractionate to be useful for quantitative evaluations of operating parameters in an offsite sample, although it may be possible to obtain limited qualitative information for an onsite sample.