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Anne Ingeborg Myhr Terje Traavik 《Journal of Agricultural and Environmental Ethics》2003,16(3):227-247
Risk governance of GM plants and GMfood products is presently subject to heatedscientific and public controversies. Scientistsand representatives of the biotechnologyindustry have dominated debates concerningsafety issues. The public is suspicious withregard to the motives of scientists, companies,and political institutions involved. Thedilemmas posed are nested, embracing valuequestions, scientific uncertainty, andcontextual issues. The obvious lack of data andinsufficient information concerning ecologicaleffects call for application of thePrecautionary Principle (PP). There are,however, divergent opinions among scientistsabout the relevance of putative hazards,definition of potential ``adverse effects,' andwhether actions should be taken to preventharm. The reliance on the concept ofsubstantial equivalence in safety evaluation ofGM food is equally controversial. Consequently,value assumptions embedded in a scientificframework may be a barrier for employment ofthe PP. One of our major conclusions is thatprecautionary GMP usage requires riskassessment criteria yet undeveloped, as well asbroader and more long-term conceptions of risk,uncertainty, and ignorance. Conflicts ofinterest and public participation are otherissues that need to be taken intoconsideration. GMP governance regimes that arejustifiable from a precautionary and ethicalpoint of view must transcend traditionalscientific boundaries to include alternativescientific perspectives as well as publicinvolvement. 相似文献
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Anne Ingeborg Myhr Terje Traavik 《Journal of Agricultural and Environmental Ethics》2003,16(4):315-316
Editorial Introduction
From the editors 相似文献6.
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Ingeborg L. A. Boxman 《Food and environmental virology》2010,2(3):156-166
Different sources were consulted to obtain information on the occurrence of viruses in bivalve molluscs on the European market.
Twenty-six peer-reviewed articles were identified reporting on the molecular detection of viral RNA in 4,260 samples in total.
The data obtained will be presented geographically on virus types detected, the origin and treatment of the shellfish, and
the detection technique applied. The data demonstrate that viral RNA can be detected in shellfish from polluted areas, in
depurated shellfish as well as those for human consumption. The European Rapid Alert System for Food and Feed (RASFF) database
was consulted as another source. Twenty-eight notifications were identified on the presence of hepatitis A virus or norovirus
in shellfish on the European market. The most recent report of the European laboratory network was referred to, to gain insight
into the laboratory capability at present for the analyses of shellfish on the presence of viruses. Approximately 67% of 27
participating laboratories obtained intended results for all samples, consisting of lenticules loaded with 103 copies norovirus (genogroup I (GGI) and/or genogroup II (GGII)) and/or 1 × 105–8 × 104 copies of hepatitis A virus. From 1993, there has been a continuous development of molecular detection techniques and tools
have been described to ensure quality assurance. End product testing will, however, not be achievable. As depuration has been
shown not to be effective for the complete elimination of viruses, shellfish should not be in contact with faecal contaminated
water in order to minimise the risk of shellfish-transmittable viral diseases. 相似文献
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Jiaen Liu Dr Willy Lissens Paul Devroey Andre Van Steirteghem Ingeborg Liebaers 《黑龙江环境通报》1993,13(9):873-880
The efficiency of the polymerase chain reaction (PCR) in detecting the cystic fibrosis (CF) ΔF508 mutation (which is the most common mutation of CF) was assessed in single human blastomeres. Twenty-one human immature oocytes (germinal-vesicle-stage oocytes) that had been donated for research were matured in vitro and a single spermatozoon from a carrier of the CF ΔF508 mutation was injected into the ooplasm. Fourteen embryos were obtained after intracytoplasmic sperm injection (ICSI). PCR analysis was carried out on 70 single blastomeres isolated from these 14 embryos. The results showed that the efficiency of DNA amplification by PCR in single nucleate blastomeres was 94 per cent (59/63). There were no false-positive results since none of the blank samples or the blastomeres without a nucleus showed an amplified signal. We found that nine embryos were homozygous for the unaffected genotype and that four embryos were heterozygous since they contained both the unaffected and the ΔF508 genotype. In a four-cell embryo, we observed the homozygous unaffected genotype in one blastomere and a heterozygous ΔF508/unaffected genotype in the other three blastomeres. 相似文献