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1.
Bass B Economou V Lee CK Perks T Smith SA Yip Q 《Environmental monitoring and assessment》2003,85(2):199-219
Indoor environmental health is now recognized as an important factor in preventing respiratory health problems in the United States. It is also a concern in Canada due to the amount of time that Canadians spend indoors because of cold weather and the potential for increased time indoors during the summer if theclimate warms. The negative health effects are often labeled assick building syndrome, but diagnosing a building or itsoccupants as sick is complicated by the variety of symptoms, thepresence of chronic versus acute symptoms and social andpsychological (socio-psychological) factors that may reduce theeffectiveness of an engineering solution. As a case study, thecontribution of various factors to indoor environmental health,in three buildings at the University of Toronto, was examinedusing five different methods. The results indicate that theinhabitants of the buildings consider features other than airquality in considering building health such as design,maintenance, funding cuts and socio-psychological factors. 相似文献
2.
Gulzar Kassam Andrew T. L. Chen Marshall F. Goldberg Suzanne Trusler Godfrey P. Oakley Jr. 《黑龙江环境通报》1984,4(3):213-216
Although prenatal genetic diagnosis can usually provide prospective parents with information as to whether their fetus is affected with certain genetic conditions, the presence of twins and the uncertainty about the phenotype of some chromosome variations pose a major dilemma and make genetic counselling very difficult. Here, a case report of an unusual chromosome aberration (pericentric inversion of chromosome no. 17) in a twin pregnancy which was originally suspected to be monoamniotic but later proved to have two sacs was presented. 相似文献
3.
Maguelone G. Forest Hervé Bétuel Philippe Couillin André Boué Michel David Daniel Floret René Francois Pierre Guibaud Henri Plauchu Raphaël Rappaport 《黑龙江环境通报》1981,1(3):197-207
Amniotic fluid (AF) levels of 17-hydroxyprogesterone (17OHP) and testosterone (T) were determined at 16–17 weeks in 17 pregnancies at risk for CAH and results compared to 75 normal controls. The fetus was predicted to be unaffected in 12 cases on the findings of normal AF levels of both 17OHP and T and the latter allowed a correct prediction of fetal sex in all instances. HLA typing confirmed normality in 12 cases revealing 5 carriers, 5 homozygous normal and 2 indeterminate. Steroid levels of the 2 groups were similar. Three fetuses were predicted to be CAH affected on unambiguously high levels of 17OHP and T (in female only). HLA typing was in agreement, and the diagnosis was confirmed in 2 abortuses and a female newborn by physical and hormonal studies. In the last 2 cases AF levels of OHP and T were normal but HLA (A/B/C) genotypes were identical to the CAH affected siblings. Normal physical and hormonal findings in the 2 aborted fetuses would exclude the possibility of an in utero virilizing form of CAH. The discrepancy could be explained on the basis that the fetuses had an allelic form of 21-hydroxylase deficiency or on the basis of recombination (not fully tested). It is concluded that a fully informative prenatal diagnosis of CAH should not rely entirely on HLA typing but on hormonal studies. 相似文献
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Emerging Tools for Continuous Nutrient Monitoring Networks: Sensors Advancing Science and Water Resources Protection
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Brian A. Pellerin Beth A. Stauffer Dwane A. Young Daniel J. Sullivan Suzanne B. Bricker Mark R. Walbridge Gerard A. Clyde Jr. Denice M. Shaw 《Journal of the American Water Resources Association》2016,52(4):993-1008
Sensors and enabling technologies are becoming increasingly important tools for water quality monitoring and associated water resource management decisions. In particular, nutrient sensors are of interest because of the well‐known adverse effects of nutrient enrichment on coastal hypoxia, harmful algal blooms, and impacts to human health. Accurate and timely information on nutrient concentrations and loads is integral to strategies designed to minimize risk to humans and manage the underlying drivers of water quality impairment. Using nitrate sensors as the primary example, we highlight the types of applications in freshwater and coastal environments that are likely to benefit from continuous, real‐time nutrient data. The concurrent emergence of new tools to integrate, manage, and share large datasets is critical to the successful use of nutrient sensors and has made it possible for the field of continuous monitoring to rapidly move forward. We highlight several near‐term opportunities for federal agencies, as well as the broader scientific and management community, that will help accelerate sensor development, build and leverage sites within a national network, and develop open data standards and data management protocols that are key to realizing the benefits of a large‐scale, integrated monitoring network. Investing in these opportunities will provide new information to guide management and policies designed to protect and restore our nation's water resources. 相似文献
7.
David M. Oliver Nick D. Hanley Melanie van Niekerk David Kay A. Louise Heathwaite Sharyl J. M. Rabinovici Julie L. Kinzelman Lora E. Fleming Jonathan Porter Sabina Shaikh Rob Fish Sue Chilton Julie Hewitt Elaine Connolly Andy Cummins Klaus Glenk Calum McPhail Eric McRory Alistair McVittie Amanna Giles Suzanne Roberts Katherine Simpson Dugald Tinch Ted Thairs Lisa M. Avery Andy J. A. Vinten Bill D. Watts Richard S. Quilliam 《Ambio》2016,45(1):52-62
The use of molecular tools, principally qPCR, versus traditional culture-based methods for quantifying microbial parameters (e.g., Fecal Indicator Organisms) in bathing waters generates considerable ongoing debate at the science–policy interface. Advances in science have allowed the development and application of molecular biological methods for rapid (~2 h) quantification of microbial pollution in bathing and recreational waters. In contrast, culture-based methods can take between 18 and 96 h for sample processing. Thus, molecular tools offer an opportunity to provide a more meaningful statement of microbial risk to water-users by providing near-real-time information enabling potentially more informed decision-making with regard to water-based activities. However, complementary studies concerning the potential costs and benefits of adopting rapid methods as a regulatory tool are in short supply. We report on findings from an international Working Group that examined the breadth of social impacts, challenges, and research opportunities associated with the application of molecular tools to bathing water regulations. 相似文献
8.
Identifying natural and anthropogenic sources of metals in urban and rural soils using GIS-based data,PCA, and spatial interpolation 总被引:2,自引:0,他引:2
Harley T. Davis C. Marjorie Aelion Suzanne McDermott Andrew B. Lawson 《Environmental pollution (Barking, Essex : 1987)》2009,157(8-9):2378-2385
Determining sources of neurotoxic metals in rural and urban soils is important for mitigating human exposure. Surface soil from four areas with significant clusters of mental retardation and developmental delay (MR/DD) in children, and one control site were analyzed for nine metals and characterized by soil type, climate, ecological region, land use and industrial facilities using readily available GIS-based data. Kriging, principal component analysis (PCA) and cluster analysis (CA) were used to identify commonalities of metal distribution. Three MR/DD areas (one rural and two urban) had similar soil types and significantly higher soil metal concentrations. PCA and CA results suggested that Ba, Be and Mn were consistently from natural sources; Pb and Hg from anthropogenic sources; and As, Cr, Cu, and Ni from both sources. Arsenic had low commonality estimates, was highly associated with a third PCA factor, and had a complex distribution, complicating mitigation strategies to minimize concentrations and exposures. 相似文献
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Suzanne J.T. Hangx Christopher J. Spiers 《International Journal of Greenhouse Gas Control》2009,3(6):757-767
Qualitative proposals to control atmospheric CO2 concentrations by spreading crushed olivine rock along the Earth's coastlines, thereby accelerating weathering reactions, are presently attracting considerable attention. This paper provides a critical evaluation of the concept, demonstrating quantitatively whether or not it can contribute significantly to CO2 sequestration. The feasibility of the concept depends on the rate of olivine dissolution, the sequestration capacity of the dominant reaction, and its CO2 footprint. Kinetics calculations show that offsetting 30% of worldwide 1990 CO2 emissions by beach weathering means distributing of 5.0 Gt of olivine per year. For mean seawater temperatures of 15–25 °C, olivine sand (300 μm grain size) takes 700–2100 years to reach the necessary steady state sequestration rate and is therefore of little practical value. To obtain useful, steady state CO2 uptake rates within 15–20 years requires grain sizes <10 μm. However, the preparation and movement of the required material poses major economic, infrastructural and public health questions. We conclude that coastal spreading of olivine is not a viable method of CO2 sequestration on the scale needed. The method certainly cannot replace CCS technologies as a means of controlling atmospheric CO2 concentrations. 相似文献