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We investigate the relationship between land-use changes (1987–2007) and the spatial distribution of the average declared income of resident population in a southern European metropolitan region (Athens, Greece) as a contribution to the analysis of suburbanization processes in the Mediterranean region. To demonstrate that urban expansion is accompanied with multiple modifications in the use of the surrounding non-urban land, we developed a computational approach based on spatial indexes of landscape configuration and proximity as a result of changes in the local socio-spatial structure. Diversity in the use of land surrounding built-up parcels in the Athens’ metropolitan region increased significantly between 1987 and 2007, reflecting a progressive fragmentation of the exurban landscape. The percentage of forests and (high-quality) natural land surrounding built-up parcels increased from 8.1 to 9.4 % between 1987 and 2007. The reverse pattern was observed for (low-quality) sparsely vegetated areas, declining from 65 to 47 %. Large built-up parcels were surrounded by a higher percentage of natural land than small parcels. The largest increase over time in forest and natural land surrounding built-up parcels was observed in municipalities with high per capita declared income, and the reverse pattern was observed for sparse vegetation. Our results demonstrate that scattered urban expansion determines a polarization in suburban areas with high-quality and low-quality natural amenities. Sprawl increases economic inequality and socio-spatial disparities contributing to a spatially unbalanced distribution of natural amenities with higher consumption of high-quality land.  相似文献   
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Fetal cerebral ventriculomegaly (VM) is diagnosed when the width of one or both ventricles, measured at the level of the glomus of the choroid plexus (atrium), is ≥ 10 mm. VM can result from different processes: abnormal turnover of the cerebrospinal fluid (CSF), neuronal migration disorders, and destructive processes. In a high percentage of cases, it is associated with structural malformations of the central nervous system (CNS), but also of other organs and systems. The rate of associated malformations is higher (≥60%) in severe VM (>15 mm) and lower (10–50%) in cases of borderline VM (10–15 mm). When malformations are not present, aneuploidies are found in 3–15% of borderline VM; the percentage is lower in severe VM. The neurodevelopmental outcome of isolated VM is normal in > 90% of cases if the measurement of ventricular width is between 10 and 12 mm; it is less favorable when the measurement is > 12 mm. Copyright © 2009 John Wiley & Sons, Ltd.  相似文献   
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