Effect of graphene oxide exposure on intestinal Wnt signaling in nematode Caenorhabditis elegans

Exposure to engineered nanomaterials(ENMs), such as graphene oxide(GO), can potentially induce the response of various molecular signaling pathways, which can mediate the protective function or the toxicity induction.Wnt signaling pathway is conserved evolutionarily in organisms.Using Caenorhabditis elegans as an in vivo assay model, we investigated the effect of GO exposure on intestinal Wnt signaling.In the intestine, GO exposure dysregulated Frizzled receptor MOM-5, Disheveled protein DSH-2, GSK-3(a component of APC complex), and two β-catenin proteins(BAR-1 and HMP-2), which mediated the induction of GO toxicity.In GO exposed nematodes, a Hox protein EGL-5 acted as a downstream target of BAR-1, and fatty acid transport ACS-22 acted as a downstream target of HMP-2.Functional analysis on HMP-2 and ACS-22 suggested that the dysregulation of these two proteins provides an important basis for the observed deficit in functional state of intestinal barrier.Our results imply the association of dysregulation in physiological and functional states of intestinal barrier with toxicity induction of GO in organisms.     

厌氧-混凝工艺处理造纸厂终端废水试验研究

本文报告了用厌氧 -混凝工艺处理造纸厂终端废水的实验情况 ,在最佳实验条件下 ,废水从CODcr80 6 . 7m g/ L、BOD52 10 . 5 m g/ L、SS2 15 . 7m g/ L、OD4 650 . 35 0降至 CODcr6 1. 5 m g/ L、BOD52 7. 4m g/ L、SS17.3mg/ L、OD4 650 .0 11。实验结果表明对造纸厂终端废水的治理 ,本工艺是很有实用价值的一种方法     

利用神经网络及数值模拟获取变压边力控制曲线

在应用Dynaform、Autoform等板料数值模拟软件的过程中 ,通常需要对压边力施力曲线进行各种预先的设定 ,但如何选定施力模式一直是一个比较棘手的问题 ,在文中利用数值模拟及MATLAB中的神经网络工具箱得出了压边力的最优控制曲线     

粉煤灰综合利用—制无烟型煤

粉煤灰,又称“烟道灰”,是从燃烧装置的烟道气中收集而得到的细灰.目前,国内外对粉煤灰的综合利用极为重视,但大部分都着眼于建材、建筑和农业等方面,而本发明是将粉煤灰作为型煤的掺合料配制型煤,即将粉煤灰与烟煤、褐煤和泥炭混配,再加入适量的添加剂,混匀后经压力成型制成各种形状的无烟燃料.实践证明,只要灰质、煤质和掺比相匹配,可压制成合格的掺灰型煤,达到“煤掺灰,灰代煤、效益高”的效果.该掺灰型煤,具有反应活性高,燃烧效果好,基本无烟等特点,投资少,见效快,效益高,节约能源等.经试烧证明,燃烧排烟中的各种污染物可消减50%以上,节约煤炭约30%以上,并且,每吨掺灰型煤(按售价每吨100元计算)可增收15—20元.     

上海地区高空气流长距离输送轨迹及其与酸雨的关系

分析了影响上海地区的高空气流输送轨迹。不同月份影响上海的高空气流来向不一。轨迹输送路径与天气系统的变化密切有关,且与上海地区出现的酸雨有关。研究表明,上海地区的酸雨,除与局地污染有关外,还与远处输送的外来污染有关。这些外来污染影响,主要来自上海西南向的北部湾和两广等地。也有部分来自东北——东方向的南朝鲜和日本西部地区。     

运用过程分析法有效推进清洁生产

运用过程分析式清洁生产审计开展清洁生产，通过对工艺过程、作业活动的过程分析，充分查找物料流失环节及废弃物的排放点．不需过多的经济投入解决物料计量问题，不需用物料衡算方法，而且查找细致、全面、有效且易于操作，不易遗漏，更有利于企业的清洁生产。     

Water pricing towards sustainability of water resources: a case study in Beijing

The role of water pricing for managing water resources is widely recognized in many areas of the world because of the increasing scarcity of water resources, a high competition between water uses and environmental degradation. Based on the analysis of cost of water, this paper explores which types of cost should be reflected in the water pricing enhancing the sustainability of water resources. The principle of full cost pricing in which the cost should include supply cost, opportunity cost and externalities is proposed as a means to achieve the sustainability of water resources. In a case study of Beijing, low water price is analyzed as one reason for unsustainable water consumption. Thus water pricing justified is necessary and pressing. It is proposed to justify water price in phased manner and eventually towards full cost pricing. The assessment of impacts on water resources by raising water price shows water pricing could alleviate the conflict between water supply and demand. This paper concludes that water pricing can play an effective role in enhancing the sustainability of water resources in Beijing.     

高强度高精度螺栓热后毛坯的矫直

利用搓丝原理 ,在自动搓丝机上 ,对热处理后的高强度螺栓毛坯进行矫直处理 ,提高了产品合格率和生产效率。     

市区餐饮娱乐业环境管理浅见

本文从实际出发对市辖区餐饮业这个突出的环境敏感问题，查摆了现象，分析了产生原因，结合现阶段市辖区餐饮业环境管理实际，提出了针对性整改的措施。     

土壤中水溶氟与总氟和土壤PH值的相关分析

使用实测资料，利用数理统计方法分析了土壤中水溶氟与总氟和土壤ＰＨ值三者间的相关关系，提出了在背景地区，土壤水溶氟与总氟、土壤ＰＨ值间无相关性；与土壤ＰＨ值间无相关性的结论。