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The presence of chemicals in laboratories and research centers exposes the staff working at such indoor environment to health risks. In this piece of research, a study was performed on the indoor environment of the Center for Environmental Engineering Research at Sahand University of Technology (Tabriz, Iran). For this purpose, the parameters affecting the dispersion of volatile organic compounds (VOCs), including ventilation rate, room temperature, pollution emission time, venting location, air flow regime within the indoor environment, and the number of vents, were simulated via CFD modeling. The CFD modeling was performed three-dimensionally in unsteady state. In case of turbulent flow within the indoor environment, k–ε turbulence model was used to obtain air velocity profile. Experimental data was used to validate the model. Results of the present research showed that when the venting location is on the ceiling, pollution concentration of 25 ppm can be achieved at some low temperature under a particular set of conditions. However, when the venting location was on the walls close to the pollution source, concentrations as low as 5 ppm and lower were observed within the laboratory indoor environment.

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