排序方式: 共有2条查询结果,搜索用时 15 毫秒
1
1.
This study was aimed at evaluating the ameliorative effect of vitamin C on chlorpyrifos-induced sensorimotor changes involving postural reflex, limb placing, and vibrissae touch in Wistar rats. Forty adult Wistar rats of either sex were divided into 4 groups of 10 animals in each group. Group I was administered soya oil (2?mL?kg?1) while group II was given vitamin C (100?mg?kg?1); group III was dosed with chlorpyrifos (10.6?mg?kg?1, i.e. ~1/8th of the LD50); group IV was administered vitamin C (100?mg?kg?1) and then exposed to chlorpyrifos (10.6?mg?kg?1), 30?min later. The regimens were administered by gavage once daily for a period of 17 weeks. Neurobehavioral parameters involving postural reflex, limb placing, and vibrissae touch responses measured at various intervals revealed a deficit in postural reflex, limb placing, and vibrissae touch responses in the CPF group, which was mitigated by vitamin C pretreatment. The neuronal and glial cell degeneration, increased brain malonaldehyde concentration, and decrease in superoxide dismutase, catalase, and acetylcholinesterase activities recorded in the group given chlorpyrifos were ameliorated by vitamin C. Therefore, vitamin C was shown to mitigate chlorpyrifos-induced sensorimotor deficits partly due to its antioxidant and acetylcholinesterase restoration properties. 相似文献
2.
Olasehinde-Williams Godwin Lee Chien-Chiang Folorunsho Ajide 《Environmental science and pollution research international》2023,30(1):547-556
Environmental Science and Pollution Research - This paper contributes to the trade-energy literature by examining the effect of export product diversification on the energy demand of 30 countries... 相似文献
1