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排序方式: 共有321条查询结果,搜索用时 31 毫秒
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Marc Trimborn Rolf-Dieter Wegner Holger Tönnies Nanette Sarioglu Matthias Albig Heidemarie Neitzel 《黑龙江环境通报》2006,26(3):273-276
We describe the first prenatally detected case of a small de novo interstitial duplication of chromosome 16q. This chromosomal aberration is extremely rare. Amniocentesis was indicated by advanced maternal age only. Ultrasound examinations of the foetus showed no abnormalities. Conventional and molecular cytogenetic analyses on cultured amniocytes by comparative genomic hybridisation (CGH) and fluorescence in situ hybridisation (FISH) using partial chromosome paints and a locus-specific YAC clone revealed a de novo direct duplication of the chromosomal region 16q11.2-q13 leading to a partial trisomy 16q (46,XX,dup(16)(q11.2q13)). There are only five postnatal reports of comparable duplications involving this chromosomal region. These patients presented with little or no associated dysmorphic features but with significant neurodevelopmental delay and severe behavioural problems. After genetic counselling, the parents opted for termination of pregnancy. Post-mortem examination showed slight facial dysmorphic signs, minor dysgenesis of the ovaries and an atypical outflow of the arteria thyroidea ima. Copyright © 2006 John Wiley & Sons, Ltd. 相似文献
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Bunge Michael Khknen Mika A. Rmisch Winfried Opel Matthias Vogler Susanne Walkow Fred Salkinoja-Salonen Mirja Lechner Ute 《Environmental science and pollution research international》2007,14(1):3-10
Background, Aims and Scope Sediments of the Spittelwasser creek are highly polluted with organic compounds and heavy metals due to the discharge of untreated
waste waters from the industrial region of Bitterfeld-Wolfen, Germany over the course of more than one century. However, relatively
few data have been published about the chloroorganic contamination of the sediment. This paper reports on the content of different
(chloro)organic compounds with special emphasis on polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/F), and chlorobenzenes. Existing concepts for the remediation of Spittelwasser sediment include
the investigation of natural attenuation processes, which largely depend on the presence of an intact microbial food web.
In order to gain more insight in terms of biological activity, we analyzed the capacity of sediment microflora to degrade
organic matter by measuring the activities of extracellular hydrolytic enzymes involved in the biogeochemical cycling of carbon,
nitrogen, phosphorus and sulfur. Furthermore, the detection of physiologically active bacteria in the sediment, particularly
of those known for their capability to reductively dehalogenate organochlorine compounds, illustrates the potential for intrinsic
bioremediation processes.
Methods PCDD/F and chlorobenzenes were analyzed by gas chromatography(GC)/mass spectrometry and GC/flame ionization detection, respectively.
The activities of hydrolytic enzymes were determined from freshly sampled sediment layers using 4-methylumbelliferyl (MUF)
or 7-amino-4-methylcoumarin-conjugated model compounds and kinetic fluorescence measurements. Physiologically active bacteria
from different sediment layers were microscopically visualized by fluorescence in situ hybridization (FISH). Specific bacteria were identified by 16S rRNA gene amplification and sequencing.
Results and Discussion The PCDD/F congener profile was dominated by dibenzofurans. In addition, the presence of specific tetra and pentachlorinated
dibenzofurans supported the assumption that extensive magnesium production was one possible source for the high contamination.
A range of other chloroorganic compounds, including several isomers of chlorobenzenes, hexachlorocyclohexane and 1,1,1-trichloro-2,2-bis
(p-chloro-phenyl)ethane (DDT), was present in the sediment. Activities of extracellular hydrolytic enzymes showed a strong
decrease in those sediment layers that were characterized by high contents of absorbable organic halogen (AOX), indicating
disturbed organic matter decay. Interestingly, an abnormal increase of cellulolytic enzyme activities below the organochlorine-rich
layers was observed, possibly caused by residual cellulose from discharges of sulfite pulping wastes. FISH revealed physiologically
active bacteria in most sediment layers from the surface down to the depth of about 60 cm, including members of Desulfitobacterium (D.) and Sulfurospirillum. The presence of D. dehalogenans was confirmed by its partial 16S rRNA gene sequence.
Conclusions Results of chemical sediment analyses demonstrated high loads of organochlorine compounds, particularly of PCDD/F. Several
years after stopping the waste water discharge to Spittelwasser creek, this sediment remains a main source for pollution of
the downstream river system by way of the ongoing mobilization of sediment during high floods. As indicated by our enzyme
activity measurements, the decomposition potential for organic matter is low in organochlorine-rich sediment layers. In contrast,
the comparably higher enzyme activities in less organochlorine-polluted sediment layers as well as the presence of physiologically
active bacteria suggest a considerable potential for natural attenuation.
Recommendations and Perspectives From our data we strongly recommend to explore the degradative capacity of sediment microorganisms and the limits for in situ activity towards specific sediment pollutants in more detail. This will give a sound basis for the integration of bioremediation
approaches into general concepts to reduce the risk that permanently radiates from this highly contaminated sediment.
Submission Editor: Dr. Henner Hollert (Henner.Hollert@urz.uniheidelberg.de) 相似文献
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Siegfried Fleischer 《Ambio-人类环境杂志》2003,32(1):2-5
引言 根系和微生物的呼吸表明土壤是一个CO2源,其释放的CO2占全球陆地呼吸所释放的CO2的一半,陆生植物直接释放的CO2构成了另一半[1,2].CO2从土壤表面直接释放到大气中或通过径流进入河流.即使在CO2产生受到完全抑制的土壤中,如在冻结和干燥土壤中无CO2产生的状态下,其最低CO2浓度被认为是地表大气中CO2的浓度[3]. 相似文献
8.
Kuangxin Zhou Matthias Barjenbruch Christian Kabbe Goulven Inial Christian Remy 《环境科学学报(英文版)》2017,29(2):151-159
Phosphorus (P) is a limited resource, which can neither be synthesized nor substituted in its essential functions as nutrient. Currently explored and economically feasible global reserves may be depleted within generations. China is the largest phosphate fertilizer producing and consuming country in the world. China''s municipal wastewater contains up to 293,163 Mg year of phosphorus, which equals approximately 5.5% of the chemical fertilizer phosphorus consumed in China. Phosphorus in wastewater can be seen not only as a source of pollution to be reduced, but also as a limited resource to be recovered. Based upon existing phosphorus-recovery technologies and the current wastewater infrastructure in China, three options for phosphorus recovery from sewage sludge, sludge ash and the fertilizer industry were analyzed according to the specific conditions in China. 相似文献
9.
Ellen M. Douglas Paul H. Kirshen Michael Paolisso Chris Watson Jack Wiggin Ashley Enrici Matthias Ruth 《Mitigation and Adaptation Strategies for Global Change》2012,17(5):537-562
We explored the possible future impacts of increased coastal flooding due to sea level rise and the potential adaptation responses
of two urban, environmental justice communities in the metropolitan Boston area of Massachusetts. East Boston is predominantly
a residential area with some industrial and commercial activities, particularly along the coastal fringe. Everett, a city
to the north of Boston, has a diversified industrial and commercial base. While these two communities have similar socioeconomic
characteristics, they differ substantially in the extent to which residents would be impacted by increased coastal flooding.
In East Boston, a large portion of residents would be flooded, while in Everett, it is the commercial/industrial districts
that are primarily vulnerable. Through a series of workshops with residents in each community, we found that the target populations
do not have an adaptation perspective or knowledge of any resources that could assist them in this challenge. Furthermore,
they do not feel included in the planning processes within their communities. However, a common incentive for both communities
was an intense commitment to their communities and an eagerness to learn more and become actively engaged in decisions regarding
climate change adaptation. The lessons that can be applied to other studies include 1) images are powerful tools in communicating
concepts, 2) understanding existing cultural knowledge and values in adaptation planning is essential to the planning process
and 3) engaging local residents at the beginning of the process can create important educational opportunities and develop
trust and consensus that is necessary for moving from concept to implementation. 相似文献
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