Quantitative modelling of crude oil toxicity using the approach of cybernetics and structured mechanisms of microbial processes

Cybernetics and structured approach to biochemical processesin microbial cells offer the status of using various cellcomponents of Azotobacter as molecular markers intoxicity assay of environmental toxicants. The intra-linkeddynamic physicochemical reactions of the basic macromolecules– DNA, protein and membrane lipids – with respect to the crudeoil in the growth environment, results in an `impulse transferfunction'. The structured effects are reduction in both DNAand protein levels, and an elevated level of lipidperoxidation products. Toxicity index (Ti) of the crude oil,at a given concentration, is the percent ratio of thesummation of the products of these `effect parameters' andtheir respective weightings, relative to control. TheEC₅₀ is the effective percent (w/v) concentration of thecrude oil at which a toxicity index of 50% was recorded, andthis corresponded with about 44% loss in nitrogen fixation ofthe diazotrophic bacterium.     

Quantitative modelling of Ostracod bioassay: assigning toxicity index to potentially chemical contaminated swimming pools

Environmental Science and Pollution Research - One of the primary objectives of any public health programme is to design a protocol that will curtail a population from being predisposed to toxic...