排序方式: 共有3条查询结果,搜索用时 15 毫秒
1
1.
Patil Sakshi Bafana Amit Naoghare Pravin K. Krishnamurthi Kannan Sivanesan Saravanadevi 《Environmental science and pollution research international》2021,28(5):4951-4974
Environmental Science and Pollution Research - Microplastics are considered to be ubiquitous and widespread emerging contaminants. They are persistent in the nature and pose considerable harm to... 相似文献
2.
Muhil Vannan Seralathan Saravanadevi Sivanesan Amit Bafan Sanjay Madanchand Kashyap Arrigo Patrizio Kannan Krishnamurthi Tapan Chakrabarti 《环境科学学报(英文版)》2014,26(11):2307-2314
Computing chemistry was applied to understand biotransforrnation mechanism of an organochlorine pesticide, endosulfan. The stereo specific metabolic activity of human CYP-2B6 (cytochrome P450) on endosulfan has been well demonstrated. Sequence and structural similarity search revealed that the bacterium Bacillus megaterium encodes CYP-BM3, which is similar to CYP-2B6. The functional similarity was studied at organism level by batch-scale studies and it was proved that B. megaterium could metabolize endosulfan to endosulfan sulfate, as CYP-2B6 does in human system. The gene expression analyses also confirmed the possible role of CYP-BM3 in endosulfan metabolism. Thus, our results show that the protein structure based in-silico approach can help us to understand and identify microbes for remediation strategy development. To the best of our knowledge this is the first report which has extrapolated the bacterial gene for endosulfan biotransformation through in silico prediction approach for metabolic gene identification. 相似文献
3.
Alimba Chibuisi G. Rudrashetti Ashwinkumar P. Sivanesan Saravanadevi Krishnamurthi Kannan 《Environmental science and pollution research international》2022,29(4):5256-5268
Environmental Science and Pollution Research - Landfill soil leachates, containing myriad of xenobiotics, increase genotoxic and cytotoxic stress–induced cell death. However, the underlying... 相似文献
1