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排序方式: 共有358条查询结果,搜索用时 15 毫秒
1.
Ossie Geifman-Holtzman Eliezer J. Holtzman Theresa J. Vadnais Vincent E. Phillips Eleanor L. Capeless Diana W. Bianchi MD 《黑龙江环境通报》1995,15(3):261-268
The objective of this study was to detect fetal HLA-DQα gene sequences in maternal blood. HLA-DQα genotypes of 70 pregnant women and their partners were determined for type A1. We specifically sought couples where the father, but not the mother, had genotype A1. In 12 women, maternal blood samples were flow-sorted. Candidate fetal cells were isolated and amplified by using PCR primers specific for a paternal HLA-DQα A1 allele. Fetal HLA-DQα A1 genotype was predicted from sorted cells; amniocytes or cheek swabs were used for confirmation. Six of twelve sorted samples had amplification products indicating the presence of the HLA-DQα A1 allele; 6/12 did not. Prediction of the fetal genotype was 100 per cent correct, as determined by subsequent amplification of amniocytes or cheek swabs. We conclude that paternally inherited uniquely fetal HLA-DQα gene sequences can be identified in maternal blood. This system permits the identification of fetal cells independent of fetal gender, and has the potential for non-invasive prenatal diagnosis of paternally inherited conditions. 相似文献
2.
Vincent A. Dutkiewicz Sofia Alvi Badar M. Ghauri M. Iqbal Choudhary Liaquat Husain 《Atmospheric environment (Oxford, England : 1994)》2009,43(10):1737-1744
We report data from a yearlong (2006–2007) study of black carbon concentrations ([BC]) measured at 5-min intervals with an Aethalometer in Karachi, Pakistan. Daily mean [BC] varied from about 1 to 15 μg m?3. However, short-term spikes exceeding 40 μg m?3 were common, occurring primarily during the morning and evening rush-hour periods. The [BC] values were highest during November through February, ~10 μg m?3, and lowest during June through September, ~2 μg m?3. Diurnal, seasonal, and day-of-the-week trends are discussed. It is demonstrated that these trends are strongly affected by meteorological patterns. A simple expression is applied to the concentration profiles to separate the effects of meteorological conditions and elucidate the underlying emissions patterns. Daily emissions varied from 14,000 to 22,000 kg of BC per day. When integrated over the year emissions for Karachi Proper were estimated at 6.7 kilometric tons per year and emissions for greater Karachi were 17.5 kilometric tons per year. Folding in the populations of each area yields BC emissions of 0.74 and 1.1 kg per person per year, respectively. Applying the model to previously collected data at Lahore, Pakistan yields emissions during November–January that are around a factor of two higher than those in Karachi, but because the BC measurements in Lahore covered only three months, no estimates of annual emissions were attempted. Given the large populations of these cities the local health impact from PM alone is expected to be severe but because of the high [BC] emissions the impact on the global climate may be equally significant. 相似文献
3.
David A. Ross Héctor M. Guzmán Vincent J. Van Hinsberg Catherine Potvin 《Journal of environmental science and health. Part. B》2016,51(10):675-687
Concentrations of eight elements were measured in Chelonia mydas and Lepidochelys olivacea eggs collected along the Pacific coast of Panama. Manganese (Mn), iron (Fe), copper (Cu), zinc (Zn), arsenic (As), cadmium (Cd), and mercury (Hg) concentrations were similar to previous reports of these species from around the world, while lead (Pb) was lower than previous reports. Cd posed the highest health risk to people who regularly eat the eggs, with average consumption rates leading to target hazard quotients (THQ) of up to 0.35 ± 0.15. Our conclusions indicate that current turtle egg consumption in isolated, coastal Pacific communities may pose a health concern for young children, and that youth and young adults should limit their consumption of turtle eggs to reduce their total intake of nonessential metals. 相似文献
4.
Cuyler Christine Rowell Janice Adamczewski Jan Anderson Morgan Blake John Bretten Tord Brodeur Vincent Campbell Mitch Checkley Sylvia L. Cluff H. Dean Côté Steeve D. Davison Tracy Dumond Mathieu Ford Barrie Gruzdev Alexander Gunn Anne Jones Patrick Kutz Susan Leclerc Lisa-Marie Mallory Conor Mavrot Fabien Mosbacher Jesper Bruun Okhlopkov Innokentiy Mikhailovich Reynolds Patricia Schmidt Niels Martin Sipko Taras Suitor Mike Tomaselli Matilde Ytrehus Bjørnar 《Ambio》2020,49(3):805-819
Ambio - Muskoxen (Ovibos moschatus) are an integral component of Arctic biodiversity. Given low genetic diversity, their ability to respond to future and rapid Arctic change is unknown, although... 相似文献
5.
The importance of potentially interacting factors in organisms responses to a stress are often ignored or underestimated in ecotoxicology. In laboratory experiments we investigated how gender, temperature and age influence the behaviour and the physiology of the freshwater amphipod Gammarus roeseli under salinity stress. Our results revealed a significant higher sensitivity of females in survival, ventilation and ionoregulation whereas no inter-age differences were reported. Water temperature also exerted a significant effect in survival and ventilation of G. roeseli. Some of those factors appeared to interact significantly. This study provides evidence that gender can affect organisms responses to a stressor and consequently has to be considered while assessing a stress impact. We discussed the potential relationships between biological and behavioural responses. 相似文献
6.
Vincent Bartolomei Matthias Sörgel Sasho Gligorovski Elena Gómez Alvarez Adrien Gandolfo Rafal Strekowski Etienne Quivet Andreas Held Cornelius Zetzsch Henri Wortham 《Environmental science and pollution research international》2014,21(15):9259-9269
Gaseous nitrogen dioxide (NO2) represents an oxidant that is present in relatively high concentrations in various indoor settings. Remarkably increased NO2 levels up to 1.5 ppm are associated with homes using gas stoves. The heterogeneous reactions of NO2 with adsorbed water on surfaces lead to the generation of nitrous acid (HONO). Here, we present a HONO source induced by heterogeneous reactions of NO2 with selected indoor paint surfaces in the presence of light (300 nm?<?λ?<?400 nm). We demonstrate that the formation of HONO is much more pronounced at elevated relative humidity. In the presence of light (5.5 W m?2), an increase of HONO production rate of up to 8.6?·?109 molecules cm?2 s?1 was observed at [NO2]?=?60 ppb and 50 % relative humidity (RH). At higher light intensity of 10.6 (W m?2), the HONO production rate increased to 2.1?·?1010 molecules cm?2 s?1. A high NO2 to HONO conversion yield of up to 84 % was observed. This result strongly suggests that a light-driven process of indoor HONO production is operational. This work highlights the potential of paint surfaces to generate HONO within indoor environments by light-induced NO2 heterogeneous reactions. 相似文献
7.
8.
Dappe Vincent Dumez Sylvain Bernard Fabien Hanoune Benjamin Cuny Damien Dumat Camille Sobanska Sophie 《Environmental science and pollution research international》2019,26(20):20092-20106
Environmental Science and Pollution Research - The rapid industrialization and urbanization of intra- and peri-urban areas at the world scale are responsible for the degradation of the quality of... 相似文献
9.