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Occupational exposure to benzene was measured in two gasoline marketing terminals and five major refineries in Singapore. A total of 280 workers were monitored over two years. This assessment was carried out with two primary objectives: (1) To find out the extent of occupational exposure to benzene in the petroleum industry in Singapore, (2) To identify suitable biomarkers for monitoring of low levels of benzene exposure. The exposure was measured in five different categories of petroleum and petrochemical workers, i.e., truck drivers, despatch assistant, process operators, oil movements operators and laboratory technicians. The results revealed wide variations in exposure, from 0.01 to 13.6 ppm for personal time weighted average (TWA) exposure over the whole workshift. The exposure of truck drivers appeared to be the highest, with geometric mean (GM) of 1.98 ppm (ranged from 0.25 to 13.6 ppm). The average benzene exposure for process operators was relative low with a GM of 0.04 ppm. Lowest benzene exposure was found in the laboratory technicians, with a GM of 0.02 ppm. As cigarette smoking is known to affect metabolism of benzene, data analyses on the relationships with environmental exposure were conducted only on the 190 nonsmokers. The results showed that urinary trans, trans-muconic acid (ttMA), unmetabolized benzene in urine (UBZ) and benzene in blood (BBZ) were better biomarkers for low level benzene exposure as compared to urinary phenolic metabolites in urine, such as hydroquinone, phenol and catechol.  相似文献   
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Cavledes CN 《Disasters》1985,9(1):70-74
From December 1982 through July 1983, Peru was plagued by disastrous consequences of El Nino/Southern Oscillation phenomenon. While the northern part of the country was devastated by torrential rains and floods, central Andean Peru endured landslides and flash floods, the southern Altiplano suffered a severe drought. Hazard preparedness was nonexistent, and official disaster relief uncoordinated and slow in coming. Administrative inefficiency magnified the stress upon the populations under disaster conditions. Provisions of disaster training from specialized international organizations is recommended as a preventive measure and as a policy to improve catastrophe-coping abilities in developing nations.  相似文献   
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