Effect of gervital in attenuating hepatotoxicity caused by methotrexate or azathioprine in adult albino rats

Environmental Science and Pollution Research - Methotrexate (MTX) and azathioprine (AZA) are chemotherapeutic, antimetabolic, and immunosuppressive agents with substantial risks such as oxidative...     

Conditioning of aluminium-based water treatment sludge with Fenton's reagent: effectiveness and optimising study to improve dewaterability

Alternative conditioning of aluminium-based drinking water treatment sludge using Fenton reagent (Fe2+/H2O2) was examined in this study. Focuses were placed on effectiveness and factors to affect such novel application of Fenton process. Experiments have demonstrated that considerable improvement of alum sludge dewaterability evaluated by capillary suction time (CST) can be obtained at the relative low concentrations of Fenton reagent. A Box-Behnken experimental design based on the response surface methodology was applied to evaluate the optimum of the influencing variables, i.e. iron concentration, hydrogen peroxide concentration and pH. The optimal values for Fe2+, H2O2, and pH are 21 mg g(-1)DS(-1)(dry solids), 105 mg g(-1)DS(-1) and 6, respectively, at which the CST reduction efficiency of 48+/-3% can be achieved, this agreed with that predicted by an established polynomial model in this study.     

Pharmaceutical compound removal efficiency by a small constructed wetland located in south Brazil

Environmental Science and Pollution Research - The fate of pharmaceuticals during the treatment of effluents is of major concern since they are not completely degraded and because of their...     

Integrating corporate social responsibility,health improvement,and community support in development programmes: a case for enhancing the application of health impact assessment in programme implementation in the Niger Delta region

Transnational corporations (TNCs) invest enormous resources in their corporate social responsibility (CSR) programmes in the Niger Delta region of Nigeria. However, the effectiveness and mode of execution of these CSR activities have been subjects of continuing debate. This research was therefore carried out to elicit the perspectives of members of four local communities about the impact of the CSR interventions in the areas of health improvement and participation by members of the communities in the Niger Delta. Semi-structured questionnaires were self-completed by 182 members of the local communities in the Niger Delta; the respondents gave detailed feedback about community feelings for TNCs and their CSR efforts. The findings showed that the people generally have negative views towards the CSR practices of the TNCs. The result of a two-paired t-test showed this to be true for both men and women (P =?.888, CI 95). While 69.8% of the respondents felt that the TNCs did not bring any development to their community, 87.9% had high fear of getting a disease due to the community they live in; interestingly, 90.1% wanted to be involved in decisions concerning their communities. This research therefore proposes the increased use of health impact assessment as an approach to integrate health considerations and community participation into the evaluation and implementation of development programmes in the Niger Delta. Such an approach has the potential to make CSR initiatives more effective, transparent, and minimise the tensions between communities and TNCs.     

Study on removal of silver and polyethylene terephthalate from exposed radiography films using enzyme protease

Journal of Material Cycles and Waste Management - In the proposed method, crude enzymes extracted from waste dry leaves of 15 different plants showing protease activity were used for removal of...