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The river Rhine has been in humanity's use for many centuries for a variety of activities. However, in our time, considerable changes in the course and the natural conditions of the river and the increasing use of the river for the discharge of wastewater has caused serious floods and major ecological problems. Since 1950, the International Commission for the Protection of the Rhine (ICPR) acts as the coordination point between the states bordering the Rhine for the development of programmes for river protection. The Sandoz disaster in 1986 was a turning point in the approach of the ICPR and the starting point for the present strategy of integrated riverbasin management. Recent developments have indicated the success of the current approach.  相似文献   
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ObjectivesThis study compares the effectiveness of two types of interventions with no intervention on the prevention of needle stick injuries (NSIs).MethodsHealth care workers, who were at risk for NSIs, were eligible for this three-armed cluster randomized controlled trial. In total, 23 hospital wards were randomly assigned to 1 of 2 intervention groups, which were given either a needle safety device and a workshop (NW; 7 wards, n = 267) or a workshop only (W; 8 wards, n = 263), or to a control group (C; 8 wards, n = 266). The primary outcome was the half-year incidence of NSIs, which was measured through questionnaires and official notification at the occupational health service at baseline (T0), 6 months (T1) and 12 months (T2) after baseline. Analysis were done by intention to treat. This study is registered as a prospective randomized trial, number NTR1207.ResultsA statistically significant difference was found between the groups for the half-year incidence of NSIs (p = 0.046) on the basis of questionnaire data with ORs for reported NSIs for the NW group compared with the control group of 0.34 (95% CI: 0.13–0.91) and 0.45 (95% CI: 0.19–1.06) for the W group compared with the control group. The officially registered NSIs during the study period showed no statistical differences between the groups.ConclusionsThe combined intervention of the introduction of needle safety devices and an interactive workshop led to the highest reduction in the number of self-reported NSIs compared to a workshop alone or no intervention.  相似文献   
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Nitrate leaching in intensive grassland- and silage maize-based dairy farming systems on sandy soil is a main environmental concern. Here, statistical relationships are presented between management practices and environmental conditions and nitrate concentration in shallow groundwater (0.8 m depth) at farm, field, and point scales in The Netherlands, based on data collected in a participatory approach over a 7-yr period at one experimental and eight pilot commercial dairy farms on sandy soil. Farm milk production ranged from 10 to 24 Mg ha(-1). Soil and hydrological characteristics were derived from surveys and weather conditions from meteorological stations. Statistical analyses were performed with multiple regression models. Mean nitrate concentration at farm scale decreased from 79 mg L(-1) in 1999 to 63 in 2006, with average nitrate concentration in groundwater decreasing under grassland but increasing under maize land over the monitoring period. The effects of management practices on nitrate concentration varied with spatial scale. At farm scale, nitrogen surplus, grazing intensity, and the relative areas of grassland and maize land significantly contributed to explaining the variance in nitrate concentration in groundwater. Mean nitrate concentration was negatively correlated to the concentration of dissolved organic carbon in the shallow groundwater. At field scale, management practices and soil, hydrological, and climatic conditions significantly contributed to explaining the variance in nitrate concentration in groundwater under grassland and maize land. We conclude that, on these intensive dairy farms, additional measures are needed to comply with the European Union water quality standard in groundwater of 50 mg nitrate L(-1). The most promising measures are omitting fertilization of catch crops and reducing fertilization levels of first-year maize in the rotation.  相似文献   
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Koos van der Bruggen   《Safety Science》2008,46(7):1137-1148
In this article some considerations are presented as a starting point for judging responsibility for infrastructural systems from a moral point of view. Infrastructural systems are essential for present day high-tech society. Without good working infrastructural systems people would hardly be able to survive. The importance and relevance of good working critical infrastructures for states and other public authorities are illustrated with some examples. Next, the meaning of the concept of responsibility in relation to infrastructural systems is developed. Outcome responsibility and remedial responsibility – developed in philosophy of law and political philosophy – are elaborated as useful concepts for dealing with responsibilities in infrastructural systems. This analysis is applied to the players on the infrastructural field: governments and other public authorities, non-state institutional actors and last but not least individual agents. In a last paragraph some conclusions are drawn, which can be applied for apportioning responsibility for infrastructures in practice.  相似文献   
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