A fragment constant QSAR model for evaluating the EC50 values of organic chemicals to Daphnia magna.

The quantitative relationship between the median effective concentration (EC50) of organic chemicals to Daphnia magna and the number of molecular fragments was investigated based on experimental EC50 values for 217 chemicals derived from the literature. A fragment constant model was developed based on a multivariate linear regression between the number of fragments and the logarithmically transformed reciprocal values of EC50. Functional correction factors were introduced into the model. The model was verified using an independent set of randomly selected data. The mean residual of the final model was 0.4 log-units. The robustness of the model was discussed based on the results of three jackknife tests.     

欧盟环保禁令的弦外之音

贸易是拉动中国经济增长的重要力量。据商务部统计，2004年中国外贸依存度近80％，居全球首位。中国加入WTO之前，经常遭遇发达国家的贸易“歧视”。为此，我们不遗余力历经15年艰苦谈判，终于在2001年9月17日如愿。多少善良的国人坚信，关税贸易壁垒的“冬天”已去，自由贸易的“春天”已经来临。     

政府必须具备绿色控制能力——访内蒙古自治区人大常委会副主任陈瑞清

现任内蒙古自治区人大常委会副主任的陈瑞清，是一位地地道道的北京人。1965年8月，他从北京中央民族学院历史系毕业，却选择了在内蒙古西部生态环境最恶劣的阿拉善盟当教师，之后又当过副旗长和副盟长，这样一干就是30年!也许正是这样一段艰苦的岁月，历练出他对生态环境保护的执着信念。1998年1月，陈瑞清由呼和浩特市副市长当选为内蒙古自治区人大常委会副主任，分管环境与资源保护的法治工作。新世纪以来，他多次呼吁生态建设产业化、经济发展生态化，循环经济实质上是生态经济，发展循环经济势在必行。[编者按]     

碳酸锶废水对生态环境的影响调查及治理方案

碳酸锶因电子工业飞速发展而身价百倍，但其生产废水的直接排放则造成了严重的环境污染，本文通过对水体、农业、渔业、人体健康和水生生物等多种因素调查，掌握了碳酸锶废水污染成因，同时提出了资源再利用方案。     

隔震连续梁桥结构以位移为基础的抗震设计方法

笔者对隔震连续梁桥结构提出了一种以位移为基础的抗震设计方法 ,建立了设计位移反应谱 ,给出了设计步骤 ,该方法可对对称与非对称隔震连续梁桥结构采用相同的设计步骤进行基于位移的抗震设计 ,最后对设计算例用振型分析和非线性时程分析验证了设计结果的合理性     

认真落实个体防护措施的相关法律规定

个体防护措施包括个体防护用品、用具、装备、材料和制度等.任何职业人群都存在个体防护问题,只是不同的人群受危害的程度不同.因此,我国相关的法律规定了个体防护的内容,强调了个体防护的重要性,从而体现了国家对职业人群的关怀.主要有:     

Effects of salinity on soil bacterial and archaeal community in estuarine wetlands and its implications for carbon sequestration: verification in the Yellow River Delta

Soils from two typical tidal salt marshes with varied salinity in the Yellow River Delta wetland were analysed to determine possible effects of salinity on soil carbon sequestration through changes in soil microbiology. The mean soil respiration (SR) of the salt water–fresh water mixing zone (MZ) was 2.89 times higher than that of the coastal zone (CZ) (4.73 and 1.63?μmol?m^?2?s^?1, respectively, p?Pseudomonas sp. and Limnobacter sp. that might have led to its higher dehydrogenase activity and respiratory rates. Additionally, the CZ possessed more Halobacteria and Thaumarchaeota with the ability to fix CO₂ than the MZ. Significantly lower soil salinity in MZ (4.25?g?kg^?1) was suitable for β-Proteobacteria, but detrimental for Halobacteria compared with CZ (7.09?g?kg^?1, p?相似文献   

Cytotoxicity and DNA damage of five organophosphorus pesticides mediated by oxidative stress in PC12 cells and protection by vitamin E

Previous studies have demonstrated that pesticides could induce cytotoxicity and genotoxicity in vivo and in vitro, and that oxidative stress may be an important factor involved. However, investigations comparing the capability of different organophosphorous (OP) compounds to induce cytotoxicity, genotoxicity and oxidative stress are limited. Hence, the aim of this paper was to access the cytotoxic and genotoxic effects of five OPs or metabolites, Acephate (ACE), Methamidophos (MET), Chloramidophos (CHL), Malathion (MAT) and Malaoxon (MAO), and to clarify the role of oxidative stress, using PC12 cells. The results demonstrated that MET, MAT and MAO caused significant inhibition of cell viability and increased DNA damage in PC12 cells at 40 mg L^?1. MAO was more toxic than the other OPs. ACE, MET, MAT and MAO increased the levels of intracellular reactive oxygen species (ROS) and malondialdehyde (MDA), and decreased the activity of superoxide dismutase (SOD), catalase (CAT) and glutathione (GSH) at 20 mg L^?1 and 40 mg L^?1 to different degrees. Pre-treatment with vitamin E(600 μM)caused a significant attenuation in the cytotoxic and genotoxic effect; pre-treatment reversed subsequent OP-induced elevation of peroxidation products and the decline of anti-oxidant enzyme activities. These results indicate that oxidative damage is likely to be an initiating event that contributes to the OP-induced cytotoxicity.     

炭纤维载体固定床厌氧发酵启动运行效果实验

以开发高效率、抗冲击性能强的高浓度有机废水沼气发酵技术为目的,用传统的 UASB反应器作为对照,研究了以炭纤维为生物膜载体的固定床厌氧反应器的启动运行效果。反应器进口废水 COD 为 5 000 mg/L, 水力停留时间 (HRT) 由213 h 逐步缩短为35 h,进水有机容积负荷(OLR)由0.56 kg COD/ (m³·d)提到3.45 kg COD/(m³·d)。结果表明,固定床反应器厌氧发酵的效率比对照高,出水 pH 值也比对照稳定;运行到第 50 d 时,固定床厌氧反应器和对照的 COD去除率分别由第 7 d 的36.56%和33.58%上升到87.9%和62.6%;固定床厌氧反应器的容积比产气率最高为1.16 m³/(m³·d),累计产气量为415.59 L,而对照的容积比产气率最高值仅为0.31 m³ /(m³·d),累计产气量为 71.66 L,前者最高容积比产气率和累计产气量分别是后者的3.74倍和5.78倍。固定床厌氧反应器的启动速度、COD 去除率和产甲烷效率显著地高于对照反应器。     

二段生物接触氧化工艺在中水回用中的特性研究

以规模小区生活污水为水源,对采用聚丙烯网状填料和强化炉渣组合填料的二段生物接触氧化工艺（以下简称二段法）进行了试验研究,试验针对本工艺的各项技术指标、影响因素以及各相关参数进行了较系统的试验测试。结果表明,反应器在第一接触氧池HRT为20 min、气水比为6∶1和第二接触氧池HRT为25 min、气水比为5∶1条件下,接触氧化池达到最佳降碳条件;反应器在第一接触沉池上升流速5.5 m/h和第二接触沉池上升流速4.5 m/h条件下,接触沉淀池达到最佳处理条件。