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The kinetics of accumulation of essential and toxic trace elements (TE) in vitally important organs were studied in small mammals typical of the Middle and Southern Ural fauna. The results revealed a discrepancy between the increased uptake of Cd, Zn, Pb, and Cu by animals and the virtually constant concentrations of heavy metals (HMs) in their organs, which could be explained by the existence of special elimination systems activated upon excessive HM uptake. It is shown that HM accumulation in animal tissues is energy-dependent and species-specific, and the effects of highly toxic TE correlate with physiological processes.  相似文献   
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