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排序方式: 共有184条查询结果,搜索用时 15 毫秒
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Bioaccumulation of heavy metals in fishes from Taihu Lake, China 总被引:9,自引:0,他引:9
The Cr,Zn,Cu,Cd,Pb contents were determined in Cyprinus carpio Linnaeus,Carassius auratus Linnaeus,Hypophthalmichthys molitrix and Aristichthys nobilis,which were caught from Meiliang Bay,Taihu Lake,a large,shallow and eutrophic lake of China.The results showed that:(1)the Cr,Cu,Pb,Cd contents in the edible parts of the four fish species were much lower than Chinese Food Health Criterion(1994),but the Zn contents were higher than the Criterion;(2)Cd contents were the highest in the liver of fish,Pb contents were almost the same in all organs of fish,Cr contents mainly enriched in the skin and gonads,Zn contents were the highest in the gonad(♀),and Cu contents were the highest in the liver;(3)the total metal accumulation was the greatest in the liver and the lowest in the muscle.The total metal accumulation was the highest in C.auratus L.This investigation indicated that fish products in Taihu Lake were still safe for human consumption,but the amount consumed should be controlled under the Chinese Food Health Criterion to avoid excessive intake of Zn. 相似文献
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过氧化氢酶活性及活性抑制的紫外分光光度测定 总被引:66,自引:3,他引:66
在体内实验条件下,测定了鲤鱼肝脏过氧化氢酶的活性。实验结果表明,过氧化氢酶的紫外分光光度法是可靠的,活性抑制结果表明,对-二硝基苯对鲤鱼肝脏过氧化氢酶无有明显的抑制作用。鲤鱼肝脏过氧化氢酶可作为一项指标用于生态毒理学研究。 相似文献
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镉致蟾蜍肝、肾脂质过氧化损伤 总被引:7,自引:0,他引:7
以腹腔注射法对蟾蜍(Bufo gargarizans)给镉(按动物体重的质量分数分别给0.1mg kg^-1,0.2mg kg^-1,0.4mg kg^-1,0.8mg kg^-1的Cd),处理7d后,测定其肝、肾丙二醛(MDA)、谷胱甘肽(GSH)含量及超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH—PX)、谷胱甘肽-S转移酶(GSH—ST)的活性.结果显示,一定浓度的镉能引起肝、肾MDA含量明显增加,而GSH含量及SOD、CAT、GSH—ST酶的活性则显著下降.提示一定浓度的镉能引起蟾蜍肝、肾组织脂质过氧化损伤,使蟾蜍肝、肾抗氧化能力、抗诱变能力降低;脂质过氧化损伤可能与GSH的耗竭、抗氧化酶SOD、CAT等酶活性的降低有关.图6参16 相似文献
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应用氢化物原子荧光法,测定鲤鱼肝脏中痕量Hg和As,该法具有原子吸收和原子发射光谱两种技术优势,同时它具有分析灵敏度高,干扰少,线性范围宽,可多元素同时测定等优点;在KBH4-酸还原体系中同时测定鱼肝中Hg和As,方法检出限分别为Hg:0.33ng/ml和As0.36ng/ml,线性范围分别为:0.1-2.0ng/ml和1.0-20.0ng/ml。加标回收率分别为Hg:96.0%和As:100.6%。分析结果可靠,方法令人满意,并适合大批量样品的分析。 相似文献
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Wilfried Sanchez Benjamin Piccini Jean-Marc Porcher 《Journal of environmental science and health. Part. B》2013,48(1):65-70
The aim of this study was to characterize biomarker responses in three-spined sticklebacks exposed to prochloraz (Pcz). For this purpose, adult sticklebacks were exposed for 2 weeks to prochloraz at 0, 10, 50, 100 and 500 μg/L prior to one week of depuration in clean water. At days 7, 14 and 21, several hepatic biomarkers were measured including 7-ethoxyresorufin-O-deethylase (EROD), glutathione-S-transferase (GST), glutathione peroxidase (GPx), catalase (CAT), total glutathione (GSH) content and thiobarbituric acid reactive substances (TBARS). Pcz induced a transient increase of antioxidant enzymes and a depletion of glutathione content during the first 7 days of exposure. This study showed that EROD activity and antioxidants were disrupted in a transient manner. GST was rapidly induced in a dose-dependent manner and this induction was persistent and observed also after depuration. GST appeared as a valuable biomarker to assess the exposure to Pcz. 相似文献
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R.R. Dalvi T.J. Robbins M.K. Williams D.P. Deoras F. Donastorg C. Banks 《Journal of environmental science and health. Part. B》2013,48(8-9):703-712
Abstract A single i.p. dose (120 mg/kg) of thiram given to male Sprague‐Dawley rats caused a significant increase in the activity of SGOT and SGPT 24 hr post‐treatment indicating liver damage. A considerable diminution in the serum cholinesterase activity was also noted in the treated rats as against the control animals. Additional evidence for thiram‐induced liver toxicity is provided by the observation that there was approximately 50% inhibition of the activity of hepatic microsomal benzphetamine N‐demethylase with a concomitant decrease in the concentration of cytochrome P‐450, an important component of the mixed‐function oxidase system. Although not significant, hepatic glutathione levels were also depleted by thiram, probably making the liver susceptible to toxic injury. 相似文献