左炔诺孕酮对稀有鮈鲫脂质代谢的干扰效应

为探究孕激素左炔诺孕酮（LNG）对鱼类脂质代谢的影响,将刚孵化的稀有鮈鲫仔鱼置于0.8和6.5ng/L LNG暴露6个月至性成熟,考察其生长指标、肝脏组织病理学变化、脂质和脂蛋白含量及脂质代谢相关基因的表达情况.结果显示：（1）0.8,6.5ng/L LNG暴露显著降低70dph稀有鮈鲫的体重和肥满度,且6.5ng/L LNG暴露显著降低180dph雌、雄鱼的体长或体重;（2）0.8,6.5ng/L LNG暴露导致180dph成鱼肝脏出现细胞空泡、肝细胞肿胀等损伤;（3）0.8,6.5ng/L LNG暴露显著降低180dph雌鱼肝脏中甘油三酯、胆固醇的含量,且6.5ng/L LNG暴露显著降低雌鱼血浆中甘油三酯的含量,但对雄鱼肝脏及血浆的脂质含量无显著影响;（4）0.8,6.5ng/L LNG暴露显著降低180dph雌鱼肝脏中脂肪酸合成酶基因（fasn） mRNA的表达水平,且6.5ng/L LNG暴露显著降低180dph雄鱼肝脏中fasn及乙酰辅酶A羧化酶基因（acaca） mRNA的表达水平.由此可见,LNG长期低剂量暴露可抑制稀有鮈鲫的生长、诱导肝细胞损伤、引起肝脏和血浆脂质含量发生性别差异性变化,并影响肝脏中脂质代谢相关基因的表达,表明LNG在低浓度下可干扰稀有鮈鲫的脂质代谢,提示LNG对鱼类种群具有较高的潜在生态风险.     

南京市建筑施工环境噪声的管理与对策

针对建筑施工环境噪声扰民问题投诉居高不下，提出环境监理部门要积极宣传环保法律法规，规范举报工作，认真受理投诉，以取得市民的理解与支持；严格审批夜间建筑施工，加大监管力度，做好对夜间施工现场的核查；加强行风建设，通过内强素质，提高自身的业务水平，监督与服务并重；拓展工作思路，加强与建工、公安、市容、市政供电等部门的合作，共同解决噪声扰民问题。     

Status and Trends of Dissolved Oxygen in Corpus Christi Bay, Texas, U.S.A.

The purpose of this studywas to determine status and long-term trends of dissolved oxygen concentrations (DO) in Corpus Christi Bay, Texas, U.S.A. A 20-year record of randomized stations was used to determine the trend of surface water DO, salinity, and temperature over space and time. A 13-year record of two fixed stations was used to determine the temporal nutrient trends. A 10-year record of fixed stations in the southeastern region of Corpus Christi Bay was used to determine the status of disturbance caused by low DO in bottom waters. From 1982 to 2002, there was a significant decrease in surface water DO at a rate of 0.06 mg L⁻¹ yr⁻¹ and a significant increase in surface water temperature at a rate of 0.07°C yr⁻¹. The southeastern region of Corpus Christi Bay had the lowest average DO, and during July and August, DO are steadily declining at a rate of 0.09 mg L⁻¹ yr⁻¹. It is not likely that eutrophication is causing hypoxia, because freshwater inflow rates have significantly decreased since 1941 and nutrient levels have not changed from 1987 to 2000. Even though long-term trends indicate that average surface DO is decreasing, disturbance by hypoxia appears to be stable, but this may be due to just eight years of data. In fact, if the current trend continues, surface water DO will not meet exceptional aquatic life standards (≤5 mgL⁻¹) in 2032.     

加强高校党风廉政建设努力营造和谐育人环境

首先从巩固党的执政地位、完成党的执政使命,培养中国特色社会主义事业合格建设者和可靠接班人,构建社会主义和谐社会方面论述了加强高校党风廉政建设的重要意义.在此基础上,将个别高校在党风廉政建设中存在的主要问题归纳为商业腐败、人事腐败、学术腐败、证书腐败、评估腐败等五大方面.并进一步指出:要有效治理高校党风政风中存在的问题,高校党委、纪委应在加强学习,提高认识,注重教育,完善制度,强化监督等方面做出不懈努力.     

我国目前伤亡事故接连发生和难以遏制的致因是违背人类工效学原理

运用人类工效学的基本原理与方法。指出一些企业任意延长劳动工时，无视劳动保护和劳动保障。事故发生后对事故的分析不全面、不科学。是导致我国目前伤亡事故频频发生的致因。     

依靠科技进步,促进环保事业深入发展

回顾了从１９７３年至今的２０年中，上海市环保科技工作的成绩：取得了丰硕的科研成果：汇集了雄厚的科技力量：科研装备水平逐步迈向现代化；形成了环保科技信息网络：对外合作取得了显著成绩，进一步明确了环保科技工作的指导思想：以“科学技术是第一生产力”的观点认识环境，管理环境，建设环境；从把上海建成人与自然和谐的国际级城市的高度，发展环保科技工作，贯彻可持续发展的战略于环保科技工作的全过程；以深化改革促进环     

建设项目"三同时"制度中存在的问题及分析

本文就我国“三同时”制度实施中存在的问题进行了较全面的剖析，并针对这些问题提出了解决的办法，为我国进一步完善“三同时”制度，拓展“三同时”管理的内涵，制订有关“三同时”管理细则提供了有价值的参考。     

Chromosome preparations of both direct and long-term cultures from the same fragment of chorionic villi

A simplified method is described for processing both direct preparations and long-term cultures from the same fragment of chorionic villi. Enzyme separation of the outer trophoblast layers (used for direct preparations) from the inner mesenchymal core (used to initiate long-term cultures) facilitates the utilization of the same fragments for the two procedures, without jeopardizing the success of either method. This has proved useful in cases where the sample was so small that only one method of chromosome preparation may have been possible using other techniques.     

Effect of long-term fertilization on soil nitrate distribution

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