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Blood level of calcium fractions (ionized and bound), phosphates, magnesium and albumin were measured in non‐insulin dependent diabetic patients (NIDD). Results were compared with healthy controls to elucidate the pathogenesis of probable changes of these elements. Total ionized calcium and magnesium showed significant decrease (p<0.001, p<0.05 and p<0.05) respectively. Phosphates showed non‐significant decrease while albumin reported nearly similar results. Positive correlation between inorganic phosphates and ionized calcium (r = 0.48, p<0.05) was observed only in healthy control group, not in diabetics. This may be attributed to alteration of ions excretions under diabetic condition through unknown mechanism. Additive increase of heparin sodium units in vitro to normal blood resulted in progressive fall in ionized calcium. Significant decrease was only observed upon addition of higher unit (5IU/ml). This must be taken into consideration biochemically for plasma determination of ionized calcium. 相似文献
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湖北省碘缺乏病流行特征及防治对策 总被引:1,自引:1,他引:0
湖北省碘缺乏病的流行分布与地势、地貌,土壤,地层岩性,饮水中的碘含量以及构造带密切相关,给病区居民供应碘盐和改善生态环境缺碘状况,是防治碘缺乏病的根本措施。 相似文献
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Weng HX Yan AL Hong CL Qin YC Pan L Xie LL 《Environmental geochemistry and health》2009,31(3):401-411
Radioactive iodide (125I) is used as a tracer to investigate the fate and transport of iodine in soil under various leaching conditions as well as
the dynamic transfer in a soil–plant (Chinese cabbage) system. Results show that both soils (the paddy soil and the sandy
soil) exhibit strong retention capability, with the paddy soil being slightly stronger. Most iodine is retained by soils,
especially in the top 10 cm, and the highest concentration occurs at the top most section of the soil columns. Leaching with
1–2 pore volume water does not change this pattern of vertical distributions. Early breakthrough and long tailing are two
features observed in the leaching experiments. Because of the relatively low peak concentration, the early breakthrough is
really not an environmental concern of contamination to groundwater. The long tailing implies that the retained iodine is
undergoing slow but steady release and the soils can provide a low but stable level of mobile iodine after a short period.
The enrichment factors of 125I in different plant tissues are ranked as: root > stem > petiole > leaf, and the 125I distribution in the young leaves is obviously higher than that in the old ones. The concentrations of 125I in soil and Chinese cabbage can be simulated with a dual-chamber model very well. The biogeochemical behaviors of iodine
in the soil-cabbage system show that cultivating iodized cabbage is an environmentally friendly and effective technique to
eliminate iodine deficiency disorders (IDD). Planting vegetables such as cabbage on the 129I-contaminated soil could be a good remediation technique worthy of consideration. 相似文献
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IntroductionIodineisakeyelementcomposingthyroxin ,whichplaysanimportantroleinthegrowthofthehumanbody.Thyroxinpromotesproteinsynthesis,regulatesenergyconversion ,preservesthecompositionofcentralnervoussystem ,andmaintainsnormalmetabolism .Therefore ,oncethe… 相似文献
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Sohel Q. Saikat Joy E. Carter Aradhana Mehra Barry Smith Alex Stewart 《Environmental geochemistry and health》2004,26(3-4):395-401
Endemic goitre was prevalent in the population of Derbyshire in the UK for many centuries until it declined from the 1930s. A contemporary medical survey showed that endemicity of goitre was particularly higher in the Carboniferous limestone areas of the Derbyshire-Peak District. Unlike classical goitrous areas of the world, where the distribution of goitre has been found to be related to the iodine content in the environment, there is no such relationship reported for the Derbyshire-Peak District area. The present study reviews the presence of endemic goitre in this area with reference to iodine in different environmental media using past and present data. In comparison with the world average values, the iodine contents in the soil and sediment in the Peak District are not deficient, but compared to England, Wales and Scotland averages, these levels are low. As no information on the mobility and bioavailability of iodine of this area is available, a cautious approach is necessary before any assumption is made on the aetiology of endemic goitre. The study also discusses some hypotheses relating to the possible cause of endemic goitre in the limestone areas. Further research needs are suggested depending on the land use and geochemistry of the Peak District to determine the underlying causes of the former endemic goitre in this area. 相似文献
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This paper attempts to discuss the links between the geochemical composition of rocks and minerals and the geographical distribution of diseases in human beings in Nigeria. We know that the natural composition of elements in our environment (in the bedrock, soils, water, and vegetation) may be the major cause of enrichment or depletion in these elements and may become a direct risk to human health. Similarly, anthropogenic activities such as mining and mineral processes, industrial waste disposal, agriculture, etc., could distort the natural geochemical equilibrium of the environment. Thus, the enrichment or depletion of geochemical elements in the environment are controlled either by natural and/or anthropogenic processes. The increased ingestion of toxic trace elements such as As, Cd, Hg, Pb, and F, whether directly or indirectly, adversely affects human health. Of these, Cd has most dangerous long-term effect on human health. Environmental exposure to As and Hg is a causal factor in human carcinogenesis and numerous cancer health disorders. Available information on iodine deficiency disorder (IDD) in Nigeria indicates goiter prevalence rates of between 15% and 59% in several affected areas. There have been reported cases of dental fluorosis resulting from intake of water with fluoride content >1.5 ppm. Dental caries among children shows an overall prevalence rate of 39.9%. Within the Younger Granite province in central Nigeria, cases of cancer and miscarriages in pregnant women have been linked to natural radiation These examples and a number of others from the existing literature underscore the pressing need for the development of collaborative research to increase our understanding of the relationship between the geographical distribution of human and animal diseases in Nigeria and environmental factors. We submit that such knowledge is essential for the control and management of these diseases. 相似文献
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