钢铁企业安全管理ERP应用初探

ERP在企业应用的不断推广,为安全管理ERP的产生奠定了基础.在企业应用安全管理ERP可以加强各类行为监控,降低事故风险,规范作业流程,有效提高企业安全管理水平和效率,值得推广和应用.     

A comprehensive approach to API RP 752 and 753 building siting studies

Facility siting studies are an important part of process safety, and are required for facilities that fall under OSHA’s PSM program. Facility siting is frequently interpreted as performing a building siting study which adheres to the guidance given in API RP 752. Building siting may also consider siting of temporary or portable buildings based on the guidance in API RP 753. While both API RP 752 and API RP 753 provide a framework and some guidance for performing building siting studies, they do not provide detailed methodologies or provide guidance on performing a detailed analysis. As a result many building siting studies are inconsistent in their overall approach, or in the way they address hazards. Due to the recent scrutiny applied to building siting studies, more attention has been given to provide evaluations which correctly describe the range of hazards that may affect an occupied building at a petrochemical facility. This paper outlines a comprehensive methodology for performing building siting studies at such facilities. The methodology addresses the applicable hazards and the available tools by which the potential impacts to building occupants can be evaluated.     

水体表面微层中DBP和DEHP的色谱测定

建立了用气相色谱（ＧＣ）和反相高效液相色谱（ＲＰＨＰＬＣ）分析邻苯二甲酸二丁酯（ＤＢＰ）和邻苯二甲酸二异辛酯（ＤＥＨＰ）的方法。首次在ＨＰＬＣ中用异丙醇作为流动相分离上述两种化合物,取得满意的结果。ＧＣ的检测限为ＤＢＰ２ｎｇ,ＤＥＨＰ２ｎｇ。ＨＰＬＣ的检测限为ＤＢＰ５ｎｇ,ＤＥＨＰ１０ｎｇ。两种方法都有良好的精密度、回收率,并用这两种分析方法分析了湖水水体表面微层水样中的ＤＢＰ和ＤＥＨＰ     

Combining Stated Preference and Revealed Preference Methods for the Valuation of Non-market Goods

In this paper, we introduce the combining stated pref- erence and revealed preference methods which is the state-of- the-art method for the valuation of non-market goods. Revealed preference methods an...     

超声提取反相高效液相色谱测定土壤中的微量硫双威

采用超声提取反相高效液相色谱测定土壤中微量硫双威的含量,以甲醇作提以剂,对超声提取的条件进行了选择,提取物在反相ＯＤＳ柱上用甲醇／水作流动相,紫外检测器进行检测,方法的线性范围宽,精密度和准确度好。     

抗生素单一及联合暴露对RP4质粒介导的抗性基因水平转移的hormesis效应研究

抗生素滥用导致的抗性基因(ARGs)泛滥问题引起人们的日益关注。目前关于抗性基因的研究主要集中在环境监测方面,但是关于抗生素对ARGs传播的影响研究还相对缺乏。质粒是ARGs传播的重要载体,因此以基于RP4质粒的大肠杆菌(E.coli)接合转移体系为研究对象,探讨了盐酸四环素、甲氧苄啶、磺胺氯哒嗪、磺胺异唑在单一暴露条件下对RP4质粒接合转移的影响。根据单一暴露的结果设计混合抗生素的浓度比,探究抗生素联合暴露实验对质粒接合转移的影响。结果表明:在单一暴露条件下,只有盐酸四环素对含有四环素抗性的RP4质粒的接合转移频率有低促高抑的hormesis效应;在联合暴露条件下,对RP4质粒接合转移无促进作用的抗生素会抑制四环素的hormesis效应,这一定程度上降低了抗生素的环境风险。并且用受体理论解释了抗生素对质粒接合转移的hormesis效应产生机制,为目前尚无定论的hormesis受体理论机制提供了证据支持。     

离子液体[BMIm][PF6]增强抗性质粒RP4介导的接合转移基因mRNA的表达水平

环境中广泛存在的抗生素和抗生素抗性基因会导致很严重的人类健康风险。在我们前期研究中发现,离子液体1-丁基-3-甲基咪唑六氟磷酸盐([BMIm][PF6])作为环境选择性压力可以促进抗生素抗性基因的水平转移。本研究以E.coli DH5α(RP4)和同属的E.coli HB101,以及E.coli DH5α(RP4)和跨属的Salmonella enterica之间的纯菌接合转移体系为考察对象,从mRNA基因表达调控水平角度阐明离子液体[BMIm][PF6](0.001~2.5 g·L-1)影响质粒RP4接合转移的机理。结果表明,离子液体[BMIm][PF6]通过抑制基因kor A,kor B和trb A的mRNA表达水平来提高接合和跨膜转运基因trb Bp和trf Ap的表达;增强水平转移基因tra F的mRNA表达水平,并通过增强负调控基因kil A和kil B的mRNA表达水平抑制质粒的垂直传递过程;通过抑制基因trb K的mRNA表达水平降低接合转移体系的排斥效果,从而促进质粒RP4的接合转移。该结果有助于为抗生素抗性基因在环境中水平转移扩散的机理研究提供理论依据。     

Combining Stated Preference and Revealed Preference Methods for the Valuation of Non-market Goods

Abstract

In this paper, we introduce the combining stated preference and revealed preference methods which is the state-ofthe- art method for the valuation of non-market goods. Revealed preference methods and stated preference (SP) methods have both been applied by economists in valuing non-market goods; however both methods have inherent weaknesses. In order to exploit the strengths of the various approaches while minimizing their weaknesses, combining the two methods has become an important methodological option. Up to now, a growing number of literatures of studying combing the two types of data have evolved, and researchers developed three types of models to estimate combining revealed preference and stated preference data in academic fields: discrete choice model, continuous choice model and mixed choice model. Combining stated and revealed preference methods have been developed fast especially in the transport study field in which ideas could also be leant for environmental economic studies.     

Prenatal diagnosis of X-linked retinitis pigmentosa (RP) in five pregnancies at risk

Five pregnancies at risk for X-linked retinitis pigmentosa (RP) have been monitored by first-trimester prenatal diagnosis using DNA markers flanking the RP2 and RP3 loci. Three affected and two unaffected fetuses, including a female carrying a wild-type genotype, were predicted on the basis of marker segregation and estimation of the recombination fraction.     

应用RP技术快速制造金属/陶瓷零件和模具

详细归纳、总结了目前己经成功用于制造金属 /陶瓷零件的各种方法 ,结合具体研究实例 ,依据转换法 (Transfer)和间接法 (Indirect)两大类 ,分类讨论了用RP技术制造金属 /陶瓷零件和模具方法。首先 ,根据转换法制造过程的特点 ,分类叙述了其成形工艺 ,并对该方法的特点和寿命进行了评判。对间接法 ,根据不同的成形系统 ,总结了成形金属 /陶瓷件和模具的最新进展。最后 ,提出了未来研究和发展的方向。