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1.
International safety regulations such as EN 1127-1 consider ultrasound to be an ignition source. Currently, applications of ultrasound in explosive atmospheres have to comply with a threshold value of 1 mW/mm2. However, it is unclear as to how this intensity has to be measured and, therefore, this threshold value is poorly defined. Moreover, it is based on theoretical estimations in analogy to other ignition sources and there are no publications or significant records on these estimations. Within a research project at PTB, it has now been investigated experimentally in relation to worst-case considerations including airborne ultrasound, focused MHz ultrasound in liquids and acoustic cavitation. On the basis of the results of the research it is now possible to revise the current regulations and to specify measures for safe operation of ultrasonic applications in explosive atmospheres. In this context, for ultrasound coupled directly to gaseous atmospheres a new threshold value of 170 dB (re. 20 μPa) can be suggested, and for ultrasonic applications in liquids, an augmentation can be made to the threshold to 400 mW/mm2. 相似文献
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Dario Paladini Maria Giovanna Russo Antonio Tartaglione Annamaria Loffredo Pasquale Martinelli 《黑龙江环境通报》2002,22(13):1185-1187
Toriello–Carey syndrome is a rare malformative complex, described for the first time in 1988, characterized by agenesis of the corpus callosum, facial anomalies, cardiac defects and hypotonia. Relatively few neonatal cases have been reported. We describe here the first prenatal ultrasound diagnosis of the syndrome based on the detection of agenesis of the corpus callosum and spongious cardiomyopathy in a 22-week-old fetus of a couple with positive family history. The first sib of the couple was diagnosed with Toriello–Carey syndrome at 1 year of age, and had, in addition to the typical facial anomalies not detectable by ultrasound, agenesis of the corpus callosum and the same heart lesion (spongious cardiomyopathy). This report demonstrates that prenatal diagnosis of Toriello–Carey syndrome is feasible in the second trimester of pregnancy. Copyright © 2002 John Wiley & Sons, Ltd. 相似文献
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Chih-Ping Chen Schu-Rern Chern Wayseen Wang Chen-Chi Lee Wen-Lin Chen Li-Feng Chen Tung-Yao Chang Chin-Yuan Tzen 《黑龙江环境通报》2001,21(5):346-350
A prenatal diagnosis of partial monosomy 18p(18p11.2→pter) and trisomy 21q(21q22.3→qter) in a fetus with alobar holoprosencephaly (HPE) and premaxillary agenesis (PMA) but without the classical Down syndrome phenotype is reported. A 27-year-old primigravida woman was referred for genetic counselling at 21 weeks' gestation due to sonographic findings of craniofacial abnormalities. Level II ultrasonograms manifested alobar HPE and median orofacial cleft. Cytogenetic analysis and fluorescence in situ hybridization (FISH) on cells obtained from amniocentesis revealed partial monosomy 18p and a cryptic duplication of 21q,46,XY,der(18)t(18;21)(p11.2;q22.3), resulting from a maternal t(18;21) reciprocal translocation. The breakpoints were ascertained by molecular genetic analysis. The pregnancy was terminated. Autopsy showed alobar HPE with PMA, pituitary dysplasia, clinodactyly and classical 18p deletion phenotype but without the presence of major typical phenotypic features of Down syndrome. The phenotype of this antenatally diagnosed case is compared with those observed in six previously reported cases with monosomy 18p due to 18;21 translocation. The present study is the first report of concomitant deletion of HPE critical region of chromosome 18p11.3 and cryptic duplication of a small segment of distal chromosome 21q22.3 outside Down syndrome critical region. The present study shows that cytogenetic analyses are important in detecting chromosomal aberrations in pregnancies with prenatally detected craniofacial abnormalities, and adjunctive molecular investigations are useful in elucidating the genetic pathogenesis of dysmorphism. Copyright © 2001 John Wiley & Sons, Ltd. 相似文献