Increased fetal nuchal fold leading to prenatal diagnosis of ring chromosome 15

We report on the prenatal diagnosis of ring chromosome 15 in a fetus with increased nuchal fold and intrauterine growth restriction (IUGR). A 27-year-old woman gravida 2, para 1 had normal maternal serum screen tests in the early second trimester of the index pregnancy. Fetal nuchal fold thickening up to 8 mm was incidentally found during the routine obstetric ultrasound scan at 20 weeks' gestation. Amniocentesis was undertaken and the fetal karyotype was found to be 46,XY,r(15) on cytogenetic study. Fluorescence in situ hybridization (FISH) using a telomeric probe of chromosome 15 demonstrated a terminal deletion on the q arm of the ring-shaped chromosome 15. This is the first report of a prenatally diagnosed case of ring chromosome 15. Moreover, nuchal fold thickness in the second trimester may have a role in its prenatal diagnosis. Copyright © 2001 John Wiley & Sons, Ltd.     

湖北银洞沟银金矿床"膝折"构造形成机理及应用

湖北银矿的开采实践证明,该矿主要矿体呈陡倾脉状,随着开采层次的深入,在矿区1 160m中段和1 110m中段的一些采场回采过程中,发现所采矿脉在纵向剖面上频繁出现"膝折".开始,由于对其认识不足,给采矿厂工作带来盲目性,并增加了难度.笔者通过对"膝折"规律的研究,分析矿区构造变形史,并探讨其形成机理,对采矿起到一定指导作用.     

牛赶冲矿段地质构造研究及其意义

本文主要对洋水磷矿区牛赶冲矿段下盘矿的断裂和褶皱构造的产状、形态、位置、对矿体的破坏程度及其形成机制等进行了综合研究,并对研究结果在矿山生产实践中的指导意义进行了阐述。     

The history of the second-trimester sonographic markers for detecting fetal Down syndrome,and their current role in obstetric practice

This review summarizes the development, history and use of second-trimester sonographic markers for the detection of fetal Down syndrome over three decades. Starting with the nuchal fold thickening in 1985 and culminating in the genetic sonogram in the 1990s. The combination of second-trimester serum screening with the ultrasound markers improved the detection rate of affected fetuses but also allowed patients to decrease their risk of carrying a fetus with Down syndrome if the genetic sonogram was normal. More recently the role of the genetic sonogram and its markers have changed with the wide spread use of first-trimester screening. This prior screening ultimately decreases the prevalence of fetal Down syndrome in the second trimester to less than 85% of what it was in the first-trimester as most fetuses with Down syndrome are now identified early. Current interpretation of the second-trimester Down syndrome markers must be based on the result of the first trimester and combined screening to achieve the most accurate risk estimate of an affected fetus. Copyright © 2010 John Wiley & Sons, Ltd.     

军用风力发电机紧固螺栓断裂失效分析

目的研究风力发电机紧固螺栓断裂失效原因。方法通过化学成分分析、力学性能分析、断口扫描分析、显微组织分析测试手段,对风力发电机紧固螺栓失效原因进行分析。结果断裂螺栓螺纹根部表面存在原始折叠缺陷,为疲劳裂纹的萌生提供了有利条件;同时,螺栓头部、紧固垫圈及法兰盘之间存在装配异常情况,外力作用下接触位置应力集中较大,有利于疲劳裂纹的萌生及进一步扩展。结论通过严格控制入厂螺栓质量,同时定期检查在服役螺栓的使用状态,及时更换存在安全隐患的螺栓,有效杜绝了紧固螺栓断裂失效情况再次发生。     

某水利枢纽坝区构造特征及其对岩溶发育规律的影响

某水利枢纽区构造基本格局形成于早白垩世的燕山运动,此时构造应力场以NE向为最大主应力方向,形成了规模较大的NE向百兴向斜;渐新世以来,区域表现为大面积的间歇性隆升,构造应力场转变以NW向为最大主应力方向,形成坝区占统治地位的NE向构造,在坚硬的岩层中形成大量节理裂隙,软弱岩层中则表现为塑性变形。这种构造特征对岩溶的发育具有控制性作用:(1)构造发育史控制了岩溶发育演化史,(2)构造运动的间歇性导致岩溶的多层性及继承性,(3)褶皱限制了岩溶呈NE向带状分布,(4)不同岩层内构造特征相异导致岩溶仅在某些岩层内较发育,(5)节理裂隙控制了岩溶发育的部位及形态规模。     

Enhanced photocatalytic activity of TiO2 by surface fluorination in degradation of organic cationic compound

Experiments were carried out to investigate the influence of TiO2 surface fluorination on the photodegradation of a representative organic cationic compound, Methylene Blue （MB）. The eleetropositive MB shows poor adsorption on TiO2 surface; its degradation performs a HO. radical-mediated mechanism. In the F-modified system, the kinetic reaction rate enlarged more than 2.5 fold that was attributed mainly to the accumulating adsorption of MB and the increased photogenerated hole available on the F-modified TiO2 surface.     

内蒙古霍各乞铜多金属矿区多期变形及对成矿的控制

以构造解析为基础.进行霍各乞铜多金属矿区M形叠加褶皱的几何学运动学和动力学解释,总结构造对矿体的控制规律:三个世代的褶皱、韧性断层及相匹配的面理大都是成矿期构造,起运矿和容矿作用,可以划分五种控矿类型;第二世代褶皱为主形变,控制地层与矿体的展布,它与第三世代褶皱叠加的复合部位是找矿的靶区.     

基于褶皱中和面的煤层气藏类型

为了指导煤层气目标区优选和勘探开发,厘清褶皱构造控制的煤层气藏富集规律.通过对褶皱中和面上下煤岩层的应力与应变特征的研究,结合煤层气成藏机制,系统分析了褶皱中和面上下煤层气藏储层应力性质、渗透率、气藏边界和盖层条件,得出了褶皱中和面上下煤层背斜与向斜煤层气藏的赋存规律.将褶皱构造控制的煤层气藏划分为向斜上层聚集低渗型、向斜下层高渗运移型、背斜上层逸散型和背斜下层富集型4种类型,并引用相应类型实例进行了验证.     

半轴套管内腔折叠产生原因及预防措施

分析了半轴套管成形过程中出现折叠的特点和形成原因 ,并根据折叠形成原因提出了相应的预防措施 ,从而解决了生产过程中存在的质量问题。