新疆地理环境与地方性甲状腺肿关系剖析

用防治干预前全疆病区收集的资料分析地方性甲状腺肿与地理环境关系．从中生代到第三纪中期，塔里木西南部发生多次海侵海退．晚第三纪喜马拉雅运动导致昆仑山脉、天山山脉和阿尔泰山上升形成三山夹两盆地的地貌．居民甲状腺肿患病率自北向南而加重，各区降水量与病情关系不明显．河流中段病情随着河流径流量增加而上升．近河床区患病率高于远离河床者．盆地倾斜平原患病率由上向下逐渐减轻．第三纪海侵区患病率远高于其它地区．海侵区远端和中段的患病率高于近端区．新疆地方性甲状腺肿分布与地理因素有明显关系．     

Assessment of Iodine Deficiency and Goitre Incidence in Parts of Yewa Area of Ogun State, Southwestern Nigeria

This study was carried out to determine the occurrence, prevalence and contributing factors to the incidence of goitre in Yewa north local government area of Ogun state, southwestern Nigeria. To achieve these objectives, soil, water, and cassava tubers were collected from four villages – Igbogila, Egua, Sawonjo and Imoto and from Lagos (about 250 m to the ocean) as a reference location, in order to determine their iodine concentrations. The results of the analyses indicated a soil mean iodine range of 2.1–5.8 μg g⁻¹; a cassava mean iodine value of 2.3–3.5 μg g⁻¹ and a drinking water mean iodine value of generally <1.0 μg L⁻¹ in all the four villages. These values of iodine in soil and water of the four villages are considered low when compared with the soil iodine value of 7.4 μg g⁻¹ and water iodine value of 6.1 μg L⁻¹ obtained from Lagos. The limestone unit of the study area remains an inhibiting factor in the bioavailability of the iodine because of its alkalinity. Statistical analysis has shown that there was significant difference between iodine concentration in the soils and the drinking water, and a correlation between the soil iodine and organic matter content at p < 0.05. The correlation between soil iodine and granulometric fractions occurred at p < 0.01. Potential goitrogens in the commonly consumed cassava products might also have contributed to the prevalence of goitre in the study area. Both the females and the adults (i.e., less mobile groups) were found to be vulnerable to goitre development in these villages.